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Top Santiago hotels

Hostal Travelers
Kind and considerate owners. Would recommend again
Reviewed on Jan 18, 2020

Hotel Plaza Los Tucanes
This super convenient hotel was a delight and a surprise. Very clean updated and right off the Pan American Highway. Excellent room and the industrial scale but home cooked goodness of the fonda downstairs just perfect. We will 100% plan on staying here every trip.
Reviewed on Apr 21, 2026

HOTEL VISTA LAGO
I had a room upstairs but it was changed to downstairs for some reason!! Room changes once I physically appear seems to be the norm here in Panama… but this property was very nice and the food was delicious 😋
Reviewed on Apr 20, 2026

The Spring Loft | Santiago
Overnight stay, fine for being overnight, not any longer. Using toilette cannot sit down knees knock wall if you are taller than 5 foot!! Not comfortable sitting sideways on it. Making coffee… powdered substance in jar on shelf with coffee and sugar is Not!! Creamer as thought…. Rude awakening for ...
Reviewed on Aug 10, 2024

Hotel Mykonos Panama
Clean and comfortable room, but no fridge. Nice pool, some tiles need replacement but otherwise good condition. Parking was crazy because of a conference but they have a big lot. The restaurant was fantastic and both my kids literally licked their plates. Coffee shop is independent and said they ...
Reviewed on Apr 13, 2026

Hotel Gran David
Clean
Reviewed on Apr 20, 2026

HOTEL CORPORATIVO PLAZA COROTÚ

Minutes from downtown Santiago, Chicho Fábrega hospital and Universidad Latina.

HOTEL PLAZA COROTÚ
Santiago Hotel & Travel Guide\n
Are you intending on spending time in Panama and looking to reserve lodgings around the bright lights of Santiago? Downtown Santiago boasts 2 modern accommodation options within a 6-mile (10-kilometer) radius.
The Hotel Mykonos Panama is a great option for your stay because it is one of the most conveniently positioned Travelocity-listed rooms, one of the few options within a short walk of the Santiago downtown area.
The Hotel Mykonos Panama is located 1 mile (1.6 kilometers) from the center of Santiago. The Hotel Vista Lago Ecoresort is a mere 7 miles (12 kilometers) away.
50 miles (83 kilometers) away from Santiago, you will reach Las Tablas, where you'll find Iglesia Santa Librada and Museo Belisario Porras. The Hotel Don Jesus and Hotel Piamonte are just some examples of the convenient long and short-stay choices in Las Tablas. Or stay in Chitre, 35 miles (59 kilometers) to the east of Santiago, where you'll find the Los Guayacanes and Gran Hotel Azuero. While in Chitre, set aside a little time to check out the Catedral San Juan Bautista and Herrera Museum.
If you are flying via Marcos A. Gelabert International Airport, you might like to book Travelocity-listed accommodation at The Canal House, or American Trade Hotel, which are both conveniently close.
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