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Top Santiago hotels

HOTEL VISTA LAGO
Wow! I can’t say enough about this place, it’s a hidden gem in Boquete. The view is spectacular, beautiful private room, very comfortable bed, spotless everything. Daniel and Andrea are very friendly and proud of their property, they have thought of every detail.Thank you for making us the most amazing ...
Reviewed on Dec 1, 2025

HOTEL PLAZA COROTÚ
They will wash and laundry for a reasonable fee.
Reviewed on Feb 24, 2025

Hotel Mykonos Panama
Everything was nice room, staff, amenities!
Reviewed on Dec 1, 2025

Hotel Gran David
Everything was very good
Reviewed on Nov 22, 2025

Hotel Galería
Everything was nice!
Reviewed on Dec 1, 2025

The Spring Loft | Santiago
Overnight stay, fine for being overnight, not any longer. Using toilette cannot sit down knees knock wall if you are taller than 5 foot!! Not comfortable sitting sideways on it. Making coffee… powdered substance in jar on shelf with coffee and sugar is Not!! Creamer as thought…. Rude awakening for ...
Reviewed on Aug 10, 2024

Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone

Hostal Travelers
Kind and considerate owners. Would recommend again
Reviewed on Jan 18, 2020

Cabañas Palma Real
Santiago Hotel & Travel Guide\n
Are you intending on spending time in Panama and looking to reserve lodgings around the bright lights of Santiago? Downtown Santiago boasts 2 modern accommodation options within a 6-mile (10-kilometer) radius.
The Hotel Mykonos Panama is a great option for your stay because it is one of the most conveniently positioned Travelocity-listed rooms, one of the few options within a short walk of the Santiago downtown area.
The Hotel Mykonos Panama is located 1 mile (1.6 kilometers) from the center of Santiago. The Hotel Vista Lago Ecoresort is a mere 7 miles (12 kilometers) away.
50 miles (83 kilometers) away from Santiago, you will reach Las Tablas, where you'll find Iglesia Santa Librada and Museo Belisario Porras. The Hotel Don Jesus and Hotel Piamonte are just some examples of the convenient long and short-stay choices in Las Tablas. Or stay in Chitre, 35 miles (59 kilometers) to the east of Santiago, where you'll find the Los Guayacanes and Gran Hotel Azuero. While in Chitre, set aside a little time to check out the Catedral San Juan Bautista and Herrera Museum.
If you are flying via Marcos A. Gelabert International Airport, you might like to book Travelocity-listed accommodation at The Canal House, or American Trade Hotel, which are both conveniently close.
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