Book Hotels in Santee, NE

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight
Dec 4 - Dec 5
Tomorrow
Dec 5 - Dec 6
This weekend
Dec 5 - Dec 7
Next weekend
Dec 12 - Dec 14

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Santee hotels

Gavins Point Lakehouse

Gavins Point Lakehouse

Yankton SD
This vacation home includes a garden and laundry facilities.
Simply Stunning
Property was stunning. Views from the home are stunning and the memories we made were u forgettable. Beds and pillows were all comfortable and the kitchen was stocked with the tools to allow you to prepare whatever upur heart desired. Communication was simple and responses were quick. Definitely ...

Reviewed on Aug 3, 2025

Get rates
Opens in a new windowGavins Point Lakehouse
Shady Creek Cabin - Family Friendly Getaway Near Lake

Shady Creek Cabin - Family Friendly Getaway Near Lake

Yankton SD
This cabin features a water park, a garden, and laundry facilities. Barbecue grills are provided for your convenience.
We had a wonderful time. The place was excellent. We enjoyed the gas fire pit and the house was clean and in great condition. I would recommend this to anyone!

Reviewed on Sep 29, 2025

Get rates
Opens in a new windowShady Creek Cabin - Family Friendly Getaway Near Lake
Haven by the Lake

Haven by the Lake

Yankton SD
This vacation home features a garden, laundry facilities, and barbecue grills.
GREAT HOST!

Reviewed on Nov 24, 2025

Get rates
Opens in a new windowHaven by the Lake
Beautiful log cabin, only 1.7 miles from lake dock by Lewis & Clark, Yankton SD

Beautiful log cabin, only 1.7 miles from lake dock by Lewis & Clark, Yankton SD

Yankton SD
This cabin featured laundry facilities and barbecue grills.
It was a wonderful property about a 5 minute drive to marina. Lots of wildlife. Property was well stocked and clean. Plenty of room for everyone. The one negative was that there is no television in the living room. So if you want to watch a game or movie as a group, there is no larger space with ...

Reviewed on Aug 6, 2025

Get rates
Opens in a new windowBeautiful log cabin, only 1.7 miles from lake dock by Lewis & Clark, Yankton SD
Cozy cabin near Lewis and Clark Lake and CJ’s at the Lake

Cozy cabin near Lewis and Clark Lake and CJ’s at the Lake

Crofton NE
Stay at this cabin in Crofton. Enjoy air conditioning. Popular attractions Deep Water Recreation Area and Lewis and Clark Lake State Recreation Area are located ...
Very nice cabin, very great location, we had a good time there, everyone there very friendly, planning on conning back again

Reviewed on Oct 26, 2025

Get rates
Opens in a new windowCozy cabin near Lewis and Clark Lake and CJ’s at the Lake
The Lake House - Lakeview with 6 bedrooms - Yankton, SD

The Lake House - Lakeview with 6 bedrooms - Yankton, SD

Yankton SD
This vacation home features a water park, a garden, and laundry facilities. Families will appreciate the arcade/game room and barbecue grills.
Great stay like always

Reviewed on Oct 19, 2025

Get rates
Opens in a new windowThe Lake House - Lakeview with 6 bedrooms - Yankton, SD
ThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18

ThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18

Yankton SD
The price is $875 total per night from Dec 5 to Dec 6
$875 total
per night
Dec 5 - Dec 6
A water park and a hot tub are featured at this smoke-free vacation home. Families will appreciate the playground and barbecue grills. Limo/town car service, ...
Great house. The deck was a great spot for hanging out and entertaining. Good amenities. Good communication from host. Would rent again if we were back in the area

Reviewed on Sep 9, 2025

Opens in a new windowThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18
Spacious Lakeview Cabin Minutes from Private Beach

Spacious Lakeview Cabin Minutes from Private Beach

Crofton NE
This cabin featured laundry facilities and barbecue grills.
The host was great and the stay was better!

Reviewed on Nov 10, 2025

Get rates
Opens in a new windowSpacious Lakeview Cabin Minutes from Private Beach
Lewis and Clark Resort

Lewis and Clark Resort

2.5 out of 5
43496 Shore Drive Yankton SD
The price is $99 total per night from Dec 7 to Dec 8
$99 total
per night
Dec 7 - Dec 8
A marina and a restaurant are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
We were upgraded to a 3 bedroom cabin for the same price.

Reviewed on Nov 24, 2025

Opens in a new windowLewis and Clark Resort
Don't see what you're looking for?
See all available properties in Santee
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Santee?
From cool amenities to extra space, kid-friendly hotels come with features that can help transform a routine family vacation into a sensational one. These Santee options make vacationing with your youngsters child's play: The whole team will enjoy their time at Private updated hunting lodge/farmhouse. Pet-friendly facilities and a barbecue grill are just a few of the things that help make this property a favorite. Bear Historic Home is another excellent choice. After an exciting day of exploring, come home to your cozy room and amenities like a king bed and animal viewing activities.
Where can I find cheap hotels in Santee?
At Travelocity you'll find really nice hotels in Santee at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santee rather than in Santee. We may find you even better rates, too.
How do I find the best Santee hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santee then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santee?
The cheapest hotel in Santee is $99. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santee?
There are 67 hotels in Santee on Travelocity.
What are the best hotels in Santee?
Santee has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santee for you!
When is the best time to visit Santee?
If you want the joy of a fun-filled trip in peak season, visit Santee during May, July and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Santee?
Based on historic data is usually the cheapest month to visit Santee. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santee?
There are multiple hotels in Santee that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santee. We have plenty of kid-friendly hotels in Santee to choose from on Travelocity!
Why book a hotel in Santee through Travelocity?
Because we have the top hotels in Santee! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santee on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santee hotel reviews by fellow wanderers

Haven by the Lake

Haven by the Lake

5 out of 5
Posted 10 days ago
Travelocity Verified Review
"GREAT HOST!"
A verified traveler stayed at Haven by the Lake
Haven by the Lake

Explore More Ways to Travel with Travelocity