Book Hotels in Santana
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Santana hotels

Omali São Tomé – Principe Collection
Praia Lagarto São Tomé
$221 nightly
The price is $255 total per night from Feb 13 to Feb 14
$255 total
Feb 13 - Feb 14
Total with taxes and fees
This resort features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free airport ...
Staff was very friendly. Food was excellent. Room was clean and well kept.
Reviewed on Dec 4, 2025

Pestana São Tomé
Avenida Marginal 12 De Julho São Tomé
Fully refundableReserve now, pay when you stay
$201 nightly
The price is $231 total per night from Jan 28 to Jan 29
$231 total
Jan 28 - Jan 29
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. Relax with a ...
Wonderful stay, great staff, easy, relaxing delightful.
Reviewed on Dec 9, 2025

Hotel Central
Rua de Angola São Tomé São Tomé
A restaurant, free self parking, and a coffee shop are among this hotel's amenities. Guests will appreciate free perks like local cuisine breakfast and WiFi ...
On my last night, I was locked out and couldn't open the outside door to enter the hotel. I tried to contact the hotel using the phone number provided on Expedia, but it wasn't updated. As a result, I had to stay at a friend's house for the night.
Reviewed on Nov 7, 2024

Hotel Praia
Praia Lagarto - Cx. Postal 61 São Tomé
$160 nightly
The price is $186 total per night from Feb 13 to Feb 14
$186 total
Feb 13 - Feb 14
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, ...
Pros: Room is very spacious and clean. Common areas also nice and generally I enjoyed a quiet atmosphere. Staff is nice, food is good. Cons: They did not honor the complementary airport transfer that is announced on line, they arranged a private taxi that charged me 20 US Dollars (for a 4 minute ...
Reviewed on Dec 6, 2023

endless horizon - Cozy house in charming Santana with WiFi
Santana Cantagalo
$149 nightly
The price is $149 total per night from Jan 31 to Feb 1
$149 total
Jan 31 - Feb 1
Total with taxes and fees
Stay at this vacation home in Santana. Enjoy free WiFi and an in-room coffeemaker. Popular attractions Boca de Inferno and Paroquia da Santissima Trindade are ...
Wonderful stay in nature
We really enjoyed our stay at the Endless Horizon. Joao and Alexander were always there to help out with things. We loved the high ceilings and of course the amazing view. The bed was very comfortable and the shower was wonderful; specious and with nice hot water. We would stay there again.
Reviewed on Dec 24, 2024

Sea House
Santana Cantagalo
$300 nightly
The price is $300 total per night from Feb 7 to Feb 8
$300 total
Feb 7 - Feb 8
Total with taxes and fees
This villa features limo/town car service, a garden, and laundry facilities. Barbecue grills are provided for your convenience.

Roça Santo António Ecolodge Hotel
Roça Santo Antonio Santana
This hotel features a restaurant, an outdoor pool, and a bar/lounge. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free ...
This is a wonderful place to stay. I loved room #1!
Reviewed on Apr 23, 2022

Jo's Nature Cabin Santana
Santana São Tomé
Stay at this cabin in Santana. Enjoy patios. Popular attractions Boca de Inferno and Cloçon Téla Chocolate Factory are located nearby.

Pool and Beach Villa in Santana
Estrada brasil Roca Uba Budo Praia Santana São Tomé
This villa doesn't skimp on freebies - guests receive free WiFi and free self parking. An outdoor pool is also provided.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Santana hotel reviews by fellow wanderers

Pestana São Tomé
5 out of 5
Posted 1 month ago
Travelocity Verified Review
"Wonderful stay, great staff, easy, relaxing delightful."
A verified traveler stayed at Pestana São Tomé

Omali São Tomé – Principe Collection
5 out of 5
Posted 2 months ago
Travelocity Verified Review
"Staff was very friendly. Food was excellent. Room was clean and well kept."
A verified traveler stayed at Omali São Tomé – Principe Collection

