Book Hotels in Santana

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Santana hotels

Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

4 out of 5
Praia Lagarto, São Tomé
$213 nightly
The price is $246 total per night from Oct 21 to Oct 22
$246 total
Oct 21 - Oct 22
Total with taxes and fees
This resort features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free airport ...
"It’s a great resort, with friendly staff who"

Reviewed on Sep 18, 2025

Opens in a new windowOmali São Tomé – Principe Collection
Sweet Guest House

Sweet Guest House

2.5 out of 5
Vila Dolores n. 087, São Tomé
Fully refundableReserve now, pay when you stay
This guesthouse features a full-service spa and a rooftop terrace. Traveling on business? Take advantage of the free WiFi in public areas and airport shuttle. ...
"A very clean comfortable good value stay 10 mins walk from the centre of town. There is good WiFi and a laundry and small shop across the road."

Reviewed on Jun 27, 2024

Get rates
Opens in a new windowSweet Guest House
Pestana São Tomé

Pestana São Tomé

5 out of 5
Avenida Marginal 12 De Julho, São Tomé
Fully refundableReserve now, pay when you stay
$206 nightly
The price is $236 total per night from Nov 2 to Nov 3
$236 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. Relax with a ...
"Good choice in São Tomé city."

Reviewed on Apr 5, 2025

Opens in a new windowPestana São Tomé
Pestana Miramar São Tomé

Pestana Miramar São Tomé

3 out of 5
Avenida Marginal 12 De Julho, São Tomé
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $170 total per night from Nov 1 to Nov 2
$170 total
Nov 1 - Nov 2
Total with taxes and fees
This resort features a restaurant, a bar/lounge, and a poolside bar. Guests will appreciate free perks like free self parking and WiFi in public areas. A terrace, ...
"Very helpful and accommodating staff"

Reviewed on Jun 7, 2024

Opens in a new windowPestana Miramar São Tomé
endless horizon - Cozy house in charming Santana with WiFi

endless horizon - Cozy house in charming Santana with WiFi

Santana
$149 nightly
The price is $149 total per night from Oct 17 to Oct 18
$149 total
Oct 17 - Oct 18
Total with taxes and fees
Stay at this vacation home in Santana. Enjoy free WiFi and an in-room coffeemaker. Popular attractions Boca de Inferno and Paroquia da Santissima Trindade are ...
Wonderful stay in nature
"We really enjoyed our stay at the Endless Horizon. Joao and Alexander were always there to help out with things. We loved the high ceilings and of course the amazing view. The bed was very comfortable and the shower was wonderful; specious and with nice hot water. We would stay there again."

Reviewed on Dec 24, 2024

Opens in a new windowendless horizon - Cozy house in charming Santana with WiFi
Sea House

Sea House

Santana
This villa features limo/town car service, a garden, and barbecue grills.
Get rates
Opens in a new windowSea House
Roça Santo António Ecolodge Hotel

Roça Santo António Ecolodge Hotel

3.5 out of 5
Roça Santo Antonio, Santana
This hotel features a restaurant, an outdoor pool, and a bar/lounge. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free ...
"This is a wonderful place to stay. I loved room #1!"

Reviewed on Apr 23, 2022

Get rates
Opens in a new windowRoça Santo António Ecolodge Hotel
Jo's Nature Cabin Santana

Jo's Nature Cabin Santana

Santana
Stay at this cabin in Santana. Enjoy patios. Popular attractions Boca de Inferno and Cloçon Téla Chocolate Factory are located nearby.
Get rates
Opens in a new windowJo's Nature Cabin Santana
Pool and Beach Villa in Santana

Pool and Beach Villa in Santana

3 out of 5
Estrada brasil Roca Uba Budo Praia, Santana, São Tomé
This villa doesn't skimp on freebies - guests receive free WiFi and free self parking. An outdoor pool is also provided.
Get rates
Opens in a new windowPool and Beach Villa in Santana
Don't see what you're looking for?
See all available properties in Santana
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Santana?
From fun amenities to rooms with bunk beds, kid-friendly hotels are equipped with features that can help turn a standard family vacation into a fantastic one. These Santana options make vacationing with your youngsters a cinch: The entire crew will enjoy staying at Roça Santo António Ecolodge Hotel. A swimming pool and a nearby beach are among the things that help make this place a popular option. Alternatively, spend your Santana escape at Vila Marilyn. Take advantage of a swimming pool, a picnic area and more here.
Where can I find cheap hotels in Santana?
At Travelocity you'll find really nice hotels in Santana at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santana rather than in Santana. We may find you even better rates, too.
How do I find the best Santana hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santana then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santana?
The cheapest hotel in Santana is $149. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santana?
There are 47 hotels in Santana on Travelocity.
What are the best hotels in Santana?
Santana has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santana for you!
When is the best time to visit Santana?
If you want the joy of a fun-filled trip in peak season, visit Santana during March, August and September. If you'd prefer the peace of off-season, book a stay during quieter months, such as February, October and December.
When is the cheapest time to stay in Santana?
Based on historic data is usually the cheapest month to visit Santana. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santana?
There are multiple hotels in Santana that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santana. We have plenty of kid-friendly hotels in Santana to choose from on Travelocity!
Why book a hotel in Santana through Travelocity?
Because we have the top hotels in Santana! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santana on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santana hotel reviews by fellow wanderers

Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

4 out of 5
Posted 1 month ago
Travelocity Verified Review
"It’s a great resort, with friendly staff who "
A verified traveler stayed at Omali São Tomé – Principe Collection
Omali São Tomé – Principe Collection