Book Hotels in Santa Cruz de la Sierra

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Santa Cruz de la Sierra hotels

Rural house (full rental) El Olivar del Marqués for 26 people

Rural house (full rental) El Olivar del Marqués for 26 people

Santa Cruz de la Sierra
A hot tub is featured at this cottage, along with a garden and laundry facilities. Barbecue grills are provided for your convenience.
Estupendo
Estuvimos muy cómodos, la casa ideal para una quedada damiliar y la ubicacion perfecta para visitar Trujillo. Adrián, el anfitrión, atento en todo momento. Repetiremos!

Reviewed on Oct 6, 2022

Get rates
Opens in a new windowRural house (full rental) El Olivar del Marqués for 26 people
Finca la Desa

Finca la Desa

3 out of 5
Carretera Nacional 5 km. 293, Miajadas, Cáceres
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $88 total per night from Oct 26 to Oct 27
$88 total
Oct 26 - Oct 27
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee shop, a ...
Buenas situación , personal amable y buena comida

Reviewed on Sep 25, 2025

Opens in a new windowFinca la Desa
Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta

4 out of 5
Calle Ballesteros 6, Trujillo, Caceres
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $67 total per night from Nov 23 to Nov 24
$67 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Great hotel, with private parking. Good breakfast, comfy bed and excellent shower. The hotel is very well placed for visiting the castle etc and lots of restaurants/ cafes in the immediate area.

Reviewed on Oct 9, 2025

Opens in a new windowEurostars Palacio Santa Marta
Parador de Trujillo

Parador de Trujillo

4 out of 5
Santa Beatriz de Silva 1, Trujillo, Caceres
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $91 total per night from Oct 29 to Oct 30
$91 total
Oct 29 - Oct 30
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 3 conference rooms, along with free WiFi in ...
Specail hotel , huge roomes in a Great location...great value for money

Reviewed on Oct 13, 2025

Opens in a new windowParador de Trujillo
Hotel Izan Trujillo

Hotel Izan Trujillo

4 out of 5
Plaza del Campillo, 1, Trujillo, Caceres
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $86 total per night from Nov 2 to Nov 3
$86 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a restaurant, a seasonal outdoor pool, and a bar/lounge. WiFi in public areas is free. Self parking, a business center, and a terrace are ...
Friendly staff, good buffet breakfast, comfortable room.

Reviewed on Oct 9, 2025

Opens in a new windowHotel Izan Trujillo
The House of Luis for 4 people

The House of Luis for 4 people

Santa Cruz de la Sierra
A hot tub is featured at this cottage, along with laundry facilities.
Get rates
Opens in a new windowThe House of Luis for 4 people
The House of Luis for 2 people

The House of Luis for 2 people

Santa Cruz de la Sierra
A hot tub is featured at this cottage, along with laundry facilities.
Get rates
Opens in a new windowThe House of Luis for 2 people
The House of Luis for 4 people

The House of Luis for 4 people

Santa Cruz de la Sierra
A hot tub is featured at this cottage, along with laundry facilities.
Get rates
Opens in a new windowThe House of Luis for 4 people
The House of Luis for 2 people

The House of Luis for 2 people

Santa Cruz de la Sierra
A hot tub is featured at this cottage, along with laundry facilities.
Get rates
Opens in a new windowThe House of Luis for 2 people
Don't see what you're looking for?
See all available properties in Santa Cruz de la Sierra
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santa Cruz de la Sierra Hotel & Travel Guide

With only 1 accommodation option within a 6-mile (10-kilometer) radius of central Santa Cruz de la Sierra, consider booking a room as soon as you know your itinerary.

The Parador de Trujillo, Extremadura, which is the nearest Travelocity-listed accommodation, lies 9 miles (14 kilometers) from the city center of Santa Cruz de la Sierra. A secondary Travelocity-listed accommodation option is the NH Trujillo Palacio de Santa Marta, situated in Extremadura, 9 miles (14 kilometers) from the downtown area of Santa Cruz de la Sierra.

The Hotel Izan Trujillo is approximately 8 miles (14 kilometers) away from the main part of Santa Cruz de la Sierra. Another hotel is the Apartamentos Arquillo, which is located 9 miles (14 kilometers) away. Some other possible places to rest your head include the Posada dos Orillas and the Hotel Rural Soterraña.

Once you have spent time in Santa Cruz de la Sierra, try and leave enough time to enjoy the other great attractions Extremadura has to offer. Admire the terrain of Extremadura's forests and rivers. In addition, you should go to some of the region's ruins and old towns. Popular pastimes in this area of Spain include mountain climbing.

The nearest places to stay in Caceres are Cabrero and Caceres Old Town. Cabrero is 55 miles (86 kilometers) to the north of Santa Cruz de la Sierra, while Caceres Old Town is 30 miles (48 kilometers) to the north. Places to stay in Cabrero include the Balneario Valle del Jerte and Agua Antigüa Casa Rural. The Atrio Restaurante Hotel and Parador de Cáceres are a number of the Travelocity-listed room options in Caceres Old Town.

Just because you and your traveling partners are having a getaway, doesn't mean you can't expand your obsession with stadium sports. Find Plaza de Toros 30 miles (49 kilometers) to the west of Santa Cruz de la Sierra. Modern visitors that like the convenience of locating a hotel in the vicinity, book a room in the NH Collection Cáceres Palacio de Oquendo or Barcelo Caceres V Centenario.

Santa Cruz de la Sierra offers some great scenic and cultural attractions; discover more at our useful Santa Cruz de la Sierra travel guide.

Frequently asked questions

What are the top kid-friendly hotels in Santa Cruz de la Sierra?
Family vacations are where amazing memories are made, but it's no secret that traveling with little ones can be challenging. These kid-friendly Santa Cruz de la Sierra hotels come with perks that aim to keep adventurers of all ages comfortable and happy: Casa Rural Doña Blanca will help make your getaway the most memorable one yet. It comes with plenty of conveniences aimed at families, such as pet-friendly facilities and front desk services. Alternatively, spend your Santa Cruz de la Sierra break at Rural house (full rental) El Olivar del Marqués for 26 people. Take advantage of cycling, a fireplace and more here.
Where can I find cheap hotels in Santa Cruz de la Sierra?
At Travelocity you'll find really nice hotels in Santa Cruz de la Sierra at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santa Cruz de la Sierra rather than in Santa Cruz de la Sierra. We may find you even better rates, too.
How do I find the best Santa Cruz de la Sierra hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santa Cruz de la Sierra then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santa Cruz de la Sierra?
The cheapest hotel in Santa Cruz de la Sierra is $67. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santa Cruz de la Sierra?
There are 86 hotels in Santa Cruz de la Sierra on Travelocity.
What are the best hotels in Santa Cruz de la Sierra?
Santa Cruz de la Sierra has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santa Cruz de la Sierra for you!
When is the best time to visit Santa Cruz de la Sierra?
If you want the joy of a fun-filled trip in peak season, visit Santa Cruz de la Sierra during January, May and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as February, November and December.
When is the cheapest time to stay in Santa Cruz de la Sierra?
Based on historic data is usually the cheapest month to visit Santa Cruz de la Sierra. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santa Cruz de la Sierra?
There are multiple hotels in Santa Cruz de la Sierra that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santa Cruz de la Sierra. We have plenty of kid-friendly hotels in Santa Cruz de la Sierra to choose from on Travelocity!
Why book a hotel in Santa Cruz de la Sierra through Travelocity?
Because we have the top hotels in Santa Cruz de la Sierra! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santa Cruz de la Sierra on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santa Cruz de la Sierra hotel reviews by fellow wanderers

Parador de Trujillo

Parador de Trujillo

5 out of 5
Posted 10 days ago
Travelocity Verified Review
"Specail hotel , huge roomes in a Great location...great value for money "
A verified traveler stayed at Parador de Trujillo
Parador de Trujillo

Explore More Ways to Travel with Travelocity