Book Hotels in Upstate South Carolina, SC

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Top Upstate South Carolina hotels

Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
Clemson SC
Free WiFi in public areas is available at this cottage.
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Opens in a new windowWooded Cottage - 3 Mi to Clemson University
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$218 nightly
The price is $240 total per night from Feb 15 to Feb 16
$240 total
Feb 15 - Feb 16
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...
Everything was wonderful. Great restaurant and vibe. So glad we made this choice

Reviewed on Jan 15, 2026

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
Hampton Inn & Suites Greenville-Downtown-RiverPlace

Hampton Inn & Suites Greenville-Downtown-RiverPlace

2.5 out of 5
171 Riverplace Greenville SC
Fully refundableReserve now, pay when you stay
$141 nightly
The price is $156 total per night from Feb 8 to Feb 9
$156 total
Feb 8 - Feb 9
Total with taxes and fees
This hotel features a 24-hour gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet ...
On site covered parking, especially if it is valet

Reviewed on Jan 20, 2026

Opens in a new windowHampton Inn & Suites Greenville-Downtown-RiverPlace
Hyatt Place Greenville Downtown

Hyatt Place Greenville Downtown

3 out of 5
128 East Broad Street Greenville SC
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $134 total per night from Feb 8 to Feb 9
$134 total
Feb 8 - Feb 9
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Extremely clean. We’re very accommodating to our pets. Friendly staff

Reviewed on Jan 18, 2026

Opens in a new windowHyatt Place Greenville Downtown
The Westin Poinsett Greenville

The Westin Poinsett Greenville

4 out of 5
120 South Main St Greenville SC
$179 nightly
The price is $197 total per night from Feb 1 to Feb 2
$197 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free ...
Great hotel Great location Great room Friendly and courteous staff

Reviewed on Jan 23, 2026

Opens in a new windowThe Westin Poinsett Greenville
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $116 total per night from Feb 1 to Feb 2
$116 total
Feb 1 - Feb 2
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
I had a cleaning issue. I informed the hotel before my stays that have chronic allergies/ asthma to make sure my room was deep cleaned because I’m highly allergic to dogs, cats, dust, etc. just about every night I would start coughing and choking. I woke checked over my headboard, picture frame and ...

Reviewed on Jan 8, 2026

Opens in a new windowEmbassy Suites Greenville Golf Resort & Conference Center
Embassy Suites by Hilton Greenville Downtown Riverplace

Embassy Suites by Hilton Greenville Downtown Riverplace

3.5 out of 5
250 Riverplace Greenville SC
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $170 total per night from Feb 8 to Feb 9
$170 total
Feb 8 - Feb 9
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public ...
Everything easy to get to and the room is very clean

Reviewed on Jan 22, 2026

Opens in a new windowEmbassy Suites by Hilton Greenville Downtown Riverplace
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $163 total per night from Feb 1 to Feb 2
$163 total
Feb 1 - Feb 2
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Room was clean for the most part. The couch had some things on it, other than that, great check in, great bar and bartenders and amazing looking lobby.

Reviewed on Jan 17, 2026

Opens in a new windowHyatt Regency Greenville
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd Greenville SC
Fully refundable
$95 nightly
The price is $105 total per night from Feb 22 to Feb 23
$105 total
Feb 22 - Feb 23
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
room spotless. staff great.

Reviewed on Jan 2, 2026

Opens in a new windowCrowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Upstate South Carolina hotel reviews by fellow wanderers

The Westin Poinsett Greenville

The Westin Poinsett Greenville

5 out of 5
Posted 13 hours ago
Travelocity Verified Review
"Great hotel Great location Great room Friendly and courteous staff"
A verified traveler stayed at The Westin Poinsett Greenville
The Westin Poinsett Greenville

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