Book Hotels in Upstate South Carolina, SC
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Top Upstate South Carolina hotels
Wooded Cottage - 3 Mi to Clemson University
Clemson SC
Free WiFi in public areas is available at this cottage.
Grand Bohemian Lodge Greenville, Autograph Collection
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
The price is $240 total per night from Feb 15 to Feb 16
$240 total
per night
Feb 15 - Feb 16
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...
Everything was wonderful. Great restaurant and vibe. So glad we made this choice
Reviewed on Jan 15, 2026
Hampton Inn & Suites Greenville-Downtown-RiverPlace
171 Riverplace Greenville SC
Fully refundableReserve now, pay when you stay
The price is $156 total per night from Feb 8 to Feb 9
$156 total
per night
Feb 8 - Feb 9
This hotel features a 24-hour gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet ...
On site covered parking, especially if it is valet
Reviewed on Jan 20, 2026
Hyatt Place Greenville Downtown
128 East Broad Street Greenville SC
Fully refundableReserve now, pay when you stay
The price is $134 total per night from Feb 8 to Feb 9
$134 total
per night
Feb 8 - Feb 9
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Extremely clean. We’re very accommodating to our pets. Friendly staff
Reviewed on Jan 18, 2026
The Westin Poinsett Greenville
120 South Main St Greenville SC
The price is $197 total per night from Feb 1 to Feb 2
$197 total
per night
Feb 1 - Feb 2
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free ...
Staff at piano lounge & bar were friendly and professional. Wish our suite was cleaner. Lots of hair on bathroom & bedroom floor.
Reviewed on Jan 17, 2026
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
The price is $116 total per night from Feb 1 to Feb 2
$116 total
per night
Feb 1 - Feb 2
A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
I had a cleaning issue. I informed the hotel before my stays that have chronic allergies/ asthma to make sure my room was deep cleaned because I’m highly allergic to dogs, cats, dust, etc. just about every night I would start coughing and choking. I woke checked over my headboard, picture frame and ...
Reviewed on Jan 8, 2026
Embassy Suites by Hilton Greenville Downtown Riverplace
250 Riverplace Greenville SC
Fully refundableReserve now, pay when you stay
The price is $170 total per night from Feb 1 to Feb 2
$170 total
per night
Feb 1 - Feb 2
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public ...
Process was simple. Room was available earlier than planned which was great. The only hiccup was the digital key did not work. Got a hard key quickly and had no problems after that
Reviewed on Jan 15, 2026
Hyatt Regency Greenville
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
The price is $163 total per night from Feb 1 to Feb 2
$163 total
per night
Feb 1 - Feb 2
This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Room was clean for the most part. The couch had some things on it, other than that, great check in, great bar and bartenders and amazing looking lobby.
Reviewed on Jan 17, 2026
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
Fully refundable
The price is $105 total per night from Feb 22 to Feb 23
$105 total
per night
Feb 22 - Feb 23
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
room spotless. staff great.
Reviewed on Jan 2, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Upstate South Carolina with star-rating
Check Upstate South Carolina Hotels by Star Rating
4 Star Hotels
11 properties
Recent Upstate South Carolina hotel reviews by fellow wanderers
Hilton Greenville
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Place is very"
A verified traveler stayed at Hilton Greenville
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