Find and compare 2 Star hotels in Upstate South Carolina

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Top Upstate South Carolina 2 Star hotels

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Jan 6 to Jan 7
$70 total
Jan 6 - Jan 7
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
7.8/10 Good! (1,001 reviews)
Love it

Reviewed on Dec 26, 2025

Opens in a new windowDays Inn by Wyndham Anderson
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $84 total per night from Jan 11 to Jan 12
$84 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
9/10 Wonderful! (1,428 reviews)
The room was clean, staffs were welcoming and the breakfast food was good.

Reviewed on Dec 28, 2025

Opens in a new windowBest Western Plus Greenville I-385 Inn & Suites
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $103 total per night from Jan 6 to Jan 7
$103 total
Jan 6 - Jan 7
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8.2/10 Very Good! (1,000 reviews)
The hotel staff were efficient and friendly.

Reviewed on Dec 26, 2025

Opens in a new windowBest Western Plus Clemson Hotel & Conference Center
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $89 total per night from Jan 11 to Jan 12
$89 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
7.8/10 Good! (666 reviews)
Good available parking. Room clean. Breakfast was minimal, but good. The tub was slippery and needed a mat. I almost fell a couple of times. I would stay here again.

Reviewed on Dec 29, 2025

Opens in a new windowQuality Inn Seneca Clemson Area US-123
ECHO Suites Extended Stay by Wyndham Spartanburg

ECHO Suites Extended Stay by Wyndham Spartanburg

2 out of 5
490 W Blackstock Road Spartanburg SC
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $81 total per night from Jan 6 to Jan 7
$81 total
Jan 6 - Jan 7
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk can provide ...
8/10 Very Good! (313 reviews)
Everything was great juts no service . Also my room had the loudest refrigerator on earth and was really hard to fall a sleep.

Reviewed on Jan 2, 2026

Opens in a new windowECHO Suites Extended Stay by Wyndham Spartanburg
Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

2 out of 5
1024 Woodruff Rd Greenville SC
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $76 total per night from Jan 19 to Jan 20
$76 total
Jan 19 - Jan 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
8.2/10 Very Good! (1,000 reviews)
This is the best microtel hotel I have ever stayed in! I will definitely book them again when I come to Greenville!

Reviewed on Dec 21, 2025

Opens in a new windowMicrotel Inn & Suites by Wyndham Greenville / Woodruff Rd
Comfort Suites Greenville Airport

Comfort Suites Greenville Airport

2.5 out of 5
1371 Garlington Road Greenville SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $111 total per night from Jan 18 to Jan 19
$111 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
9.2/10 Wonderful! (1,009 reviews)

Reviewed on Dec 29, 2025

Opens in a new windowComfort Suites Greenville Airport
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $114 total per night from Jan 13 to Jan 14
$114 total
Jan 13 - Jan 14
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
8.2/10 Very Good! (1,005 reviews)
The room was immaculate and very comfortable.

Reviewed on Dec 27, 2025

Opens in a new windowComfort Inn & Suites Clemson - University Area
Motel 6 Greenville, SC

Motel 6 Greenville, SC

2 out of 5
2015 Wade Hampton Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$50 nightly
The price is $55 total per night from Jan 5 to Jan 6
$55 total
Jan 5 - Jan 6
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. The front desk is staffed around-the-clock and laundry facilities are ...
5/10 (717 reviews)
Everything was great

Reviewed on Dec 16, 2025

Opens in a new windowMotel 6 Greenville, SC
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

2.5 out of 5
246 Congaree Road Greenville SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $92 total per night from Jan 11 to Jan 12
$92 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8/10 Very Good! (1,000 reviews)
The room was clean, the breakfast was delicious, awesome spread. Staff was friendly. Seamless and smooth.

Reviewed on Dec 30, 2025

Opens in a new windowComfort Inn Greenville - Haywood Mall
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

2 Star Hotels Upstate South Carolina

Looking to break out of your routine for some much needed rest and relaxation? Or maybe you’ve already decided it’s time for a trip and are trying to find affordable hotels in Upstate South Carolina that won’t bust your travel budget?

Upstate South Carolina 2 star hotels will give you everything you need to enjoy the city like a local, saving a ton of money so you can hit all the hot spots in town.

Have a delicious breakfast at your hotel to fuel up for your day of sightseeing, then enjoy amenities like fresh towels and linens, as well as a nice hot shower to unwind after a busy day of experiencing everything the city has to offer.

As you explore a new locale, or one you love to visit over and over, you can rest easy knowing you’re staying in a great hotel that lets you discover Upstate South Carolina and welcomes you back to a clean, comfortable room at night.

Browse Travelocity’s wide selection of 2 star hotels in Upstate South Carolina and find one that’s perfectly priced and places you next to all the best activities and sights. The town is your oyster, and we can help you seek out its secrets while sticking to your budget.

Recent Upstate South Carolina hotel reviews by fellow wanderers

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