Find and compare 2 Star hotels in Upstate South Carolina

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Top Upstate South Carolina 2 Star hotels

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
$99 nightly
The price is $110 total per night from Mar 18 to Mar 19
$110 total
Mar 18 - Mar 19
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8.2/10 Very Good! (1,006 reviews)
Clean room/friendly staff/good breakfast

Reviewed on Mar 14, 2026

Opens in a new windowBest Western Plus Clemson Hotel & Conference Center
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $97 total per night from Mar 29 to Mar 30
$97 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
9.2/10 Wonderful! (1,446 reviews)
The rooms were spacious and well appointed, and the staff were friendly and professional. Lots of great options on the free breakfast buffet, too!

Reviewed on Mar 16, 2026

Opens in a new windowBest Western Plus Greenville I-385 Inn & Suites
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

2.5 out of 5
246 Congaree Road Greenville SC
Fully refundable
$84 nightly
The price is $92 total per night from Apr 5 to Apr 6
$92 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8/10 Very Good! (1,008 reviews)
The room was clean. The staff was nice!

Reviewed on Mar 14, 2026

Opens in a new windowComfort Inn Greenville - Haywood Mall
Comfort Suites Greenville Airport

Comfort Suites Greenville Airport

2.5 out of 5
1371 Garlington Road Greenville SC
Fully refundable
$102 nightly
The price is $111 total per night from Apr 5 to Apr 6
$111 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
9.2/10 Wonderful! (1,008 reviews)
Clean, friendly staff

Reviewed on Mar 16, 2026

Opens in a new windowComfort Suites Greenville Airport
Urban Boutique Hotel, BW Signature Collection

Urban Boutique Hotel, BW Signature Collection

2.5 out of 5
536 Wade Hampton Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $71 total per night from Apr 5 to Apr 6
$71 total
Apr 5 - Apr 6
Total with taxes and fees
A bar/lounge and a 24-hour front desk are featured at this motel, along with free self parking. Guests will appreciate free perks like on-the-go breakfast and ...
8/10 Very Good! (974 reviews)
Parking was easy and no extra charges, the room smelted musty and it make our clothes smell like that.

Reviewed on Mar 14, 2026

Opens in a new windowUrban Boutique Hotel, BW Signature Collection
Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road Greenville SC
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $79 total per night from Mar 23 to Mar 24
$79 total
Mar 23 - Mar 24
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Free perks include full breakfast, free self parking, and a roundtrip airport shuttle. A 24-hour business ...
7.8/10 Good! (1,002 reviews)
N/A

Reviewed on Mar 9, 2026

Opens in a new windowBest Western Greenville Airport Inn
Sleep Inn Spartanburg Southwest

Sleep Inn Spartanburg Southwest

2.5 out of 5
501 South Blackstock Rd Spartanburg SC
Fully refundable
$60 nightly
The price is $67 total per night from Apr 16 to Apr 17
$67 total
Apr 16 - Apr 17
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
6/10 (569 reviews)
Appeared clean at first glance but quickly realized it wasnt as clean as i thought. The staff was pretty friendly. The key cards kept not working so they would have to redo them. The lobby and parking lot was clean. It wasnt thw worst but i wont choose them again unfortunately. Also i was able to ...

Reviewed on Mar 15, 2026

Opens in a new windowSleep Inn Spartanburg Southwest
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
Fully refundable
$105 nightly
The price is $117 total per night from Apr 3 to Apr 4
$117 total
Apr 3 - Apr 4
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
8.2/10 Very Good! (1,003 reviews)
Very clean and quiet place. Conveniently located for everything in the area. Staff were super nice. Would definitely return.

Reviewed on Mar 9, 2026

Opens in a new windowComfort Inn & Suites Clemson - University Area
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Mar 18 to Mar 19
$135 total
Mar 18 - Mar 19
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
9/10 Wonderful! (1,001 reviews)
Great stay again

Reviewed on Mar 7, 2026

Opens in a new windowLakeside Lodge Clemson
Quality Inn & Suites Greenville - Haywood Mall

Quality Inn & Suites Greenville - Haywood Mall

2.5 out of 5
50 Orchard Park Drive Greenville SC
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $80 total per night from Mar 22 to Mar 23
$80 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self ...
7.4/10 Good! (1,007 reviews)
Great breakfast!

Reviewed on Mar 15, 2026

Opens in a new windowQuality Inn & Suites Greenville - Haywood Mall
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

2 Star Hotels Upstate South Carolina

Looking to break out of your routine for some much needed rest and relaxation? Or maybe you’ve already decided it’s time for a trip and are trying to find affordable hotels in Upstate South Carolina that won’t bust your travel budget?

Upstate South Carolina 2 star hotels will give you everything you need to enjoy the city like a local, saving a ton of money so you can hit all the hot spots in town.

Have a delicious breakfast at your hotel to fuel up for your day of sightseeing, then enjoy amenities like fresh towels and linens, as well as a nice hot shower to unwind after a busy day of experiencing everything the city has to offer.

As you explore a new locale, or one you love to visit over and over, you can rest easy knowing you’re staying in a great hotel that lets you discover Upstate South Carolina and welcomes you back to a clean, comfortable room at night.

Browse Travelocity’s wide selection of 2 star hotels in Upstate South Carolina and find one that’s perfectly priced and places you next to all the best activities and sights. The town is your oyster, and we can help you seek out its secrets while sticking to your budget.

Recent Upstate South Carolina hotel reviews by fellow wanderers

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