Explore 118 Luxury Hotels in Northeast Missouri

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Best Luxury Hotels in Northeast Missouri

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza, St. Louis, MO
Fully refundableReserve now, pay when you stay
$629 nightly
The price is $733 total per night from Oct 2 to Oct 3
$733 total
Oct 2 - Oct 3
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.2/10 Wonderful! (550 reviews)
"Service is exceptional!!!"

Reviewed on Sep 2, 2025

Opens in a new windowThe Ritz-Carlton, St. Louis
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway, St. Louis, MO
Fully refundableReserve now, pay when you stay
$222 nightly
The price is $262 total per night from Oct 12 to Oct 13
$262 total
Oct 12 - Oct 13
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
8.8/10 Excellent! (1,013 reviews)
Thank you, Miss Yu at front desk
"Great experience and wonderful stay. Had some issues at the beginning. Front desk representative, Miss Yu helps to fix everything and turn the negative energy to extreme positive. Overall, really enjoyed the four days in this hotel"

Reviewed on Sep 14, 2025

Opens in a new window The Royal Sonesta Chase Park Plaza St. Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $119 total per night from Oct 12 to Oct 13
$119 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
8.8/10 Excellent! (2,967 reviews)
"We absolutely loved it! The kids had a blast in the pool and arcade and the staff was always friendly. Breakfast was pretty good too"

Reviewed on Sep 24, 2025

Opens in a new windowClayton Plaza Hotel & Extended Stay
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St, St. Louis, MO
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $136 total per night from Oct 12 to Oct 13
$136 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.6/10 Excellent! (1,046 reviews)
"Beautiful hotel near the Busch stadium- And the Arch no pet fees Great bar and lobby"

Reviewed on Sep 24, 2025

Opens in a new windowMagnolia Hotel St. Louis, a Tribute Portfolio Hotel
The Westin St. Louis

The Westin St. Louis

811 Spruce St, St. Louis, MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Oct 12 to Oct 13
$158 total
Oct 12 - Oct 13
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.4/10 Very Good! (1,010 reviews)
"Very quiet hotel. Very chill"

Reviewed on Sep 27, 2025

Opens in a new windowThe Westin St. Louis
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

1 Ameristar Blvd, St. Charles, MO
Fully refundableReserve now, pay when you stay
$192 nightly
The price is $224 total per night from Oct 5 to Oct 6
$224 total
Oct 5 - Oct 6
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...
8.2/10 Very Good! (1,020 reviews)
"Clean room"

Reviewed on Sep 25, 2025

Opens in a new windowAmeristar Casino Resort and Spa
Quincy Inn and Suites

Quincy Inn and Suites

224 N 36th Street, Quincy, IL
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $103 total per night from Oct 1 to Oct 2
$103 total
Oct 1 - Oct 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-in. A grocery/convenience ...
6.8/10 (1,004 reviews)
"They are always nice and welcome pets."

Reviewed on Sep 23, 2025

Opens in a new windowQuincy Inn and Suites
Moberly Inn and Suites

Moberly Inn and Suites

1200 Highway 24 East, Moberly, MO
This luxury hotel features 2 restaurants, a bar/lounge, and an outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public ...
"We did not stay there the motel was condemed The website needs to be took down"

Reviewed on Nov 12, 2018

Opens in a new windowMoberly Inn and Suites
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Northeast Missouri

5 star hotels in Northeast Missouri

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza, St. Louis, MO
$629 nightly
The price is $733 total per night from Oct 2 to Oct 3
$733 total
Oct 2 - Oct 3
Total with taxes and fees
9.2/10 Wonderful! (550 reviews)

Northeast Missouri Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Northeast Missouri luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Northeast Missouri to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Northeast Missouri will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Northeast Missouri, and plan your next opulent escape.


Northeast Missouri hotels essential information

Accommodation
2,705 hotels
Lowest Price
$103
Highest Price
$733
Popular hotels
The Royal Sonesta Chase Park Plaza St. Louis, Ameristar Casino Resort and Spa, The Ritz-Carlton, St. Louis, Moberly Inn and Suites, Quincy Inn and Suites, Clayton Plaza Hotel & Extended Stay, The Westin St. Louis, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Popular Luxury Stays in Northeast Missouri

Recent Northeast Missouri Hotel Reviews By Fellow Wanderers

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