Find a Hotel in Downtown Clayton
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Top hotels in Downtown Clayton
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $150 total per night from Dec 13 to Dec 14
$150 total
Dec 13 - Dec 14
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Ok. This is like the very first Drury hotel and it is pristine. The value is all there and it is fully 4-5 stars. The only problem is you have to pay $28+ for parking.
Reviewed on Dec 2, 2025
Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $106 total per night from Dec 11 to Dec 12
$106 total
Dec 11 - Dec 12
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
Great stay. Staff was very friendly and helpful. Highly recommend.
Reviewed on Dec 4, 2025
AC Hotel St. Louis Clayton
227 South Central Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $142 total per night from Dec 14 to Dec 15
$142 total
Dec 14 - Dec 15
Total with taxes and fees
This smoke-free hotel's 2 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the free WiFi in ...
The staff were very helpful while there! I recommend doing valet instead of self parking so you wouldn’t have to go through any hassle with finding a parking space but overall my stay was great. The bed was really comfy. I would definitely stay there again when visiting St Louis.
Reviewed on Nov 25, 2025
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $153 total per night from Dec 28 to Dec 29
$153 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Staff is wonderful. We checked in late after a long journey and they could not have been nicer to us at check in also in the restaurant and bar. We loved the vibe and the location. I’d return again if ever in the area.
Reviewed on Dec 2, 2025
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $115 total per night from Dec 19 to Dec 20
$115 total
Dec 19 - Dec 20
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Love the breakfast buffet! Something for everyone. Staff is always friendly and helpful. I plan to stay at this hotel anytime I’m near it. I always feel so welcome.
Reviewed on Nov 30, 2025
Le Méridien St. Louis Clayton
7730 Bonhomme Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $140 total per night from Dec 19 to Dec 20
$140 total
Dec 19 - Dec 20
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Small rooms but beautiful lobby.
Reviewed on Oct 27, 2025
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $120 total per night from Dec 11 to Dec 12
$120 total
Dec 11 - Dec 12
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
Great
Reviewed on Dec 2, 2025
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $111 total per night from Dec 21 to Dec 22
$111 total
Dec 21 - Dec 22
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
The room was very spacious and clean! The staff was friendly and accommodating!
Reviewed on Dec 1, 2025
Hilton St. Louis Airport
10330 Natural Bridge Rd St. Louis MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $112 total per night from Dec 14 to Dec 15
$112 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the express check-in, express check-out, and free ...
Tesla charger does not agrr
Reviewed on Dec 3, 2025
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Downtown Clayton Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Downtown Clayton area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Downtown Clayton to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Downtown Clayton are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Downtown Clayton hotel reviews by fellow wanderers
Pear Tree Inn St. Louis Airport
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Great stay. Staff was very friendly and helpful. Highly recommend. "
A verified traveler stayed at Pear Tree Inn St. Louis Airport
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