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Aug 21 - Aug 23
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Top Mytilene hotels

Akti Vigla Premium

Akti Vigla Premium

Vigla Lesvos Lesvos
$87 nightly
The price is $98 total per night from Sep 17 to Sep 18
$98 total
Sep 17 - Sep 18
Total with taxes and fees
Free WiFi in public areas, a snack bar/deli, and luggage storage are available at this aparthotel. Concierge services are provided for your convenience.
"Everything was good but bathroom is extremely small and there is no shower door. Gets totally soaked all floor when take a shower. Also sink is extremely small too and tap is too high from the sink and water splash all around. Breakfast was good and recommended it."

Reviewed on Jul 15, 2026

Opens in a new windowAkti Vigla Premium
Hotel Lesvion

Hotel Lesvion

3 out of 5
P. Kountourioti 27A Lesvos
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $127 total per night from Sep 1 to Sep 2
$127 total
Sep 1 - Sep 2
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public ...
"The breakfast was fantastic. The staff was friendly. The location was ideal: right near cafes, the harbor and Ermou St."

Reviewed on Aug 15, 2026

Opens in a new windowHotel Lesvion
Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel

4 out of 5
7, Skra str, Hatzidimitriou Park Lesvos
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $189 total per night from Sep 20 to Sep 21
$189 total
Sep 20 - Sep 21
Total with taxes and fees
A full-service spa and a hot tub are featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public areas and free internet ...
"Staff was nice. Large breakfast spread. Location is great."

Reviewed on Aug 11, 2026

Opens in a new windowTheofilos Paradise Boutique Hotel
Oikies Small Elegant Houses

Oikies Small Elegant Houses

Digalaki 17 Lesvos Lesvos Island
This guesthouse features a bar/lounge, a poolside bar, and an outdoor pool. There's no skimping on freebies - guests receive free cooked-to-order breakfast, ...
"Great place! Don’t look for anywhere else!"

Reviewed on Jul 7, 2025

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Opens in a new windowOikies Small Elegant Houses
Lasia Hotel

Lasia Hotel

3 out of 5
Neapoli, Mytilene Lesvos
This hotel features an outdoor pool and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies ...
"The property, specifically the room had a lot of dust like a haunted place that hasn’t been lived in at all. The chairs were gray covered in dust in the room, but the linens were very clean the balcony, the paint only the curtains and the carpet had a lot of dust on them."

Reviewed on Aug 13, 2026

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Opens in a new windowLasia Hotel
Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat

5 out of 5
Agrilia Lesvos
$139 nightly
The price is $169 total per night from Aug 31 to Sep 1
$169 total
Aug 31 - Sep 1
Total with taxes and fees
A full-service spa, 5 restaurants, and 3 indoor pools are all featured at this luxury hotel. Traveling on business? Take advantage of the business center and ...
"Absolutely beautiful resort with the friendliest staff! Everything was easily accessible the pools were clean and refreshing and the saunas were such a great added treat! Our room was impeccably cleaned with a stunning view! Room service with extra care; an overall wonderful experience at the Mythical ..."

Reviewed on Aug 10, 2026

Opens in a new windowMythical Coast Wellness Retreat
Loriet Hotel

Loriet Hotel

4 out of 5
Vareia, Mitilene Lesvos Lesvos Island
$121 nightly
The price is $144 total per night from Sep 17 to Sep 18
$144 total
Sep 17 - Sep 18
Total with taxes and fees
This aparthotel features a restaurant, an outdoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Relax with ...
"Our vacation at the Loriet Hotel in Mithilini was amazing. Everything was perfect. We really had very good time in there. Thanks for the hospitality and the hygiene conditions. Having new plans for coming back again."

Reviewed on Jun 27, 2026

Opens in a new windowLoriet Hotel
Elysion Hotel

Elysion Hotel

5 out of 5
Neapoli Lesvos Lesvos Island
Fully refundableReserve now, pay when you stay
$168 nightly
The price is $201 total per night from Sep 20 to Sep 21
$201 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features 2 restaurants, 3 outdoor tennis courts, and an outdoor pool. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like buffet ...
Opens in a new windowElysion Hotel
Heliotrope Hotels

Heliotrope Hotels

4 out of 5
Varia Lesvos Lesvos Island
Fully refundableReserve now, pay when you stay
$141 nightly
The price is $166 total per night from Sep 20 to Sep 21
$166 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features 2 restaurants, 4 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
Opens in a new windowHeliotrope Hotels
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Mytilene?
Take some of the trials out of traveling with kids by staying in a family-friendly Mytilene hotel. From fun amenities to services that bring a smile, these properties come with perks that'll help make your trip an effortless one: Your entourage will enjoy their time at Sofies Choice Mytilini. Free WiFi and clothes washing facilities are among the things that help make this hotel a winner. Blue Sea is also a great choice. After a big day of exploring, come home to your comfortable room and amenities like room service and front desk services.
Where can I find cheap hotels in Mytilene?
At Travelocity you'll find really nice hotels in Mytilene at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Mytilene rather than in Mytilene. We may find you even better rates, too.
How do I find the best Mytilene hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Mytilene then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Mytilene?
The cheapest hotel in Mytilene is $98. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Mytilene?
There are 181 hotels in Mytilene on Travelocity.
What are the best hotels in Mytilene?
Mytilene has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Mytilene for you!
When is the best time to visit Mytilene?
If you want the joy of a fun-filled trip in peak season, visit Mytilene during January, July and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as February, November and December.
When is the cheapest time to stay in Mytilene?
Based on historic data is usually the cheapest month to visit Mytilene. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Mytilene?
There are multiple hotels in Mytilene that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Mytilene. We have plenty of kid-friendly hotels in Mytilene to choose from on Travelocity!
Why book a hotel in Mytilene through Travelocity?
Because we have the top hotels in Mytilene! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Mytilene on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Mytilene hotel reviews by fellow wanderers

Hotel Lesvion

Hotel Lesvion

5 out of 5
Posted 5 days ago
Travelocity Verified Review
"The breakfast was fantastic. The staff was friendly. The location was ideal: right near cafes, the harbor and Ermou St."
A verified traveler stayed at Hotel Lesvion
Hotel Lesvion

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