Book Hotels in Mill Spring, MO

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Mill Spring hotels

Lake Wappapello

Lake Wappapello

2 out of 5
8005 Missouri 172 Williamsville MO
Stay at this cabin in Williamsville. Enjoy free parking. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located ...
We did loose internet connection so gps did not always help but the local stores did. Also the managers answered their phones and were so helpful in many ways! I’m very glad we went.

Reviewed on Sep 28, 2025

Get rates
Opens in a new windowLake Wappapello
Rustic Cabin in Hunters' Paradise!

Rustic Cabin in Hunters' Paradise!

Mill Spring MO
This vacation home featured laundry facilities and barbecue grills.
House and property were exactly what we were looking for. Away from people and in the woods. Owners are very nice people. Will definitely stay again next year.

Reviewed on Nov 14, 2025

Get rates
Opens in a new windowRustic Cabin in Hunters' Paradise!
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

2.5 out of 5
3109 Oak Grove Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $118 total per night from Jan 9 to Jan 10
$118 total
Jan 9 - Jan 10, 2026
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
We didn't eat breakfast . And yes the parking felt very Safe .

Reviewed on Dec 24, 2025

Opens in a new windowFairfield Inn & Suites by Marriott Poplar Bluff
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

3 out of 5
2220 N Westwood Blvd Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $119 total per night from Jan 2 to Jan 3
$119 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
We’ve stayed here many times. It’s always clean and comfortable! Beds are amazing!

Reviewed on Dec 27, 2025

Opens in a new windowDrury Inn & Suites Poplar Bluff
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2.5 out of 5
2420 Crestwood Dr Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $123 total per night from Jan 10 to Jan 11
$123 total
Jan 10 - Jan 11, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business ...
Every single time I come to this location, it always exceeds my expectations. It's always clean.They always have hot coffee and they are super friendly!! Never have anything bad to say about them

Reviewed on Dec 3, 2025

Opens in a new windowHampton Inn Poplar Bluff
Sam A Baker State Park

Sam A Baker State Park

2 out of 5
5732 State Hwy Missouri 143 Patterson MO
$125 nightly
The price is $132 total per night from Dec 31 to Jan 1
$132 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
This cabin includes a picnic area and barbecue grills. Take advantage of the free self parking.
We stayed two nights and we loved it. The property grounds and cabins are well maintained we will be back

Reviewed on Oct 5, 2025

Opens in a new windowSam A Baker State Park
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

3 out of 5
2781 N Westwood Blvd Poplar Bluff MO
Fully refundable
$105 nightly
The price is $119 total per night from Jan 2 to Jan 3
$119 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
The front desk woman was great

Reviewed on Dec 21, 2025

Opens in a new windowHoliday Inn Poplar Bluff by IHG
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $83 total per night from Dec 30 to Dec 31
$83 total
Dec 30 - Dec 31
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Luggage storage is provided and the front desk is staffed ...
It was a nice stay.

Reviewed on Dec 22, 2025

Opens in a new windowMotel 6 Poplar Bluff, MO
Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

2 out of 5
2831 N Westwood Blvd Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $64 total per night from Jan 11 to Jan 12
$64 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
The hotel room was very clean and beds were comfortable. Much more than you get for your money. Breakfast is light and simple. Overall very good hotel for short stay.

Reviewed on Dec 23, 2025

Opens in a new windowSuper 8 by Wyndham Poplar Bluff Missouri
Don't see what you're looking for?
See all available properties in Mill Spring
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Mill Spring?
From cool amenities to extra room to move, kid-friendly hotels are equipped with features that can help transform a good family vacation into an awesome one. These Mill Spring properties make traveling with children easier: The whole gang will enjoy their time at Rustic Cabin in Hunters Paradise!. A king bed and a firepit are just a few of the things that help make this hotel an appealing option. Also consider staying at Cabin 2 2 double beds. It offers pet-friendly facilities, parking facilities and ample opportunities to hang out as a family.
Where can I find cheap hotels in Mill Spring?
At Travelocity you'll find really nice hotels in Mill Spring at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Mill Spring rather than in Mill Spring. We may find you even better rates, too.
How do I find the best Mill Spring hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Mill Spring then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Mill Spring?
The cheapest hotel in Mill Spring is $64. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Mill Spring?
There are 127 hotels in Mill Spring on Travelocity.
What are the best hotels in Mill Spring?
Mill Spring has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Mill Spring for you!
When is the best time to visit Mill Spring?
If you want the joy of a fun-filled trip in peak season, visit Mill Spring during June, July and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as February, November and December.
When is the cheapest time to stay in Mill Spring?
Based on historic data is usually the cheapest month to visit Mill Spring. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Mill Spring?
There are multiple hotels in Mill Spring that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Mill Spring. We have plenty of kid-friendly hotels in Mill Spring to choose from on Travelocity!
Why book a hotel in Mill Spring through Travelocity?
Because we have the top hotels in Mill Spring! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Mill Spring on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Mill Spring hotel reviews by fellow wanderers

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"We’ve stayed here many times. It’s always clean and comfortable! Beds are amazing!"
A verified traveler stayed at Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar Bluff