Deals on vacations and trips to Mesopotamia

Save when you book Mesopotamia package deals

Choose two or more items and save on your trip:

Top Mesopotamia hotels deals

To Spiti tis Sofias

To Spiti tis Sofias

Mesopotamia, Kastoria, Western Macedonia
Free Cancellation
Reserve now, pay when you stay
$67 nightly
The price is $78 total per night
$78 total
Oct 9 - Oct 10
Total with taxes and fees
This guesthouse doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, a lobby fireplace, and a communal living room are also on offer.
Parking included
Free WiFi
Limneon Resort & Spa

Limneon Resort & Spa

4 out of 5
4th km National Road Kastoria Athens, Kastoria
Free Cancellation
Reserve now, pay when you stay
$95 nightly
The price is $120 total per night
$120 total
Oct 2 - Oct 3
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling for business? Take advantage of the free WiFi in public areas, laundry service, and conference center. Enjoy a meal in one of the 3 coffee shops/cafes and perks like free buffet breakfast and free self parking.
Pool
Breakfast included
Hotel Anastassiou

Hotel Anastassiou

2 out of 5
1st km Highway Kastoria-Athens, Kastoria, Western Macedonia
Free Cancellation
Reserve now, pay when you stay
$46 nightly
The price is $55 total per night
$55 total
Oct 3 - Oct 4
Total with taxes and fees
Ski-in/ski-out access and a restaurant are featured at this smoke-free hotel. Enjoy the ski shuttle and onsite ski storage. Unwind with a drink at the bar/lounge and enjoy perks like free valet parking and a free airport shuttle.
Free airport shuttle
Parking included
Esperos Palace Luxury & Spa Hotel

Esperos Palace Luxury & Spa Hotel

4 out of 5
Chloe Area, Kastoria, Western Macedonia
Free Cancellation
Reserve now, pay when you stay
$108 nightly
The price is $134 total per night
$134 total
Sep 28 - Sep 29
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Hot Tub
Calma Hotel & Spa

Calma Hotel & Spa

4 out of 5
3rd km Kastoria, Vitsi, Kastoria
Free Cancellation
Reserve now, pay when you stay
Get rates
A full-service spa and a gym are featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. Enjoy the seasonal outdoor pool and free perks like buffet breakfast and free self parking.
Pool
Breakfast included
Chloe Hotel

Chloe Hotel

3 out of 5
Antheon & Giasemion, Kastoria, Western Macedonia
Free Cancellation
Reserve now, pay when you stay
$103 nightly
The price is $123 total per night
$123 total
Sep 26 - Sep 27
Total with taxes and fees
This Mediterranean hotel features ski-in/ski-out access, an attached winery, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. Enjoy the outdoor tennis court and free perks like buffet breakfast and free self parking.
Breakfast included
Spa
Don't see what you're looking for?
See all available properties in Mesopotamia
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Kastoria Lake

Commune with nature and explore the great outdoors at Kastoria Lake during your travels in Kastoria. While you're in the area, stroll along the lakeside.

Kastoria Lake

Holy Monastery of Panagias Mauriotissas

Learn about the local history of Kastoria when you take a trip to Holy Monastery of Panagias Mauriotissas. While you're in the area, stroll along the lakeside.

Holy Monastery of Panagias Mauriotissas

Dragon's Lair

Explore the great outdoors at Dragon's Lair, a lovely green space in Kastoria. While you're in the area, stroll along the lakeside.

Dragon's Lair

Frequently asked questions

How much are vacation packages to Mesopotamia?
Travelocity offers great package deals to Mesopotamia, including hotels and flights, starting at just . With all the cash you save, you could book some cool tours or maybe even tack on a few extra days to your adventure.
Where can I get the best vacation package deals for Mesopotamia?
There are awesome Mesopotamia package deals to be snapped up with Travelocity. Did you know we partner with 400 airlines and 1,000,000 properties in all corners of the globe? Keep this in mind the next time you're ready to tick another place off your bucket list.
Why should I book my Mesopotamia vacation package with Travelocity?
Because you'll never wander alone if you book your vacation with us, and we offer round-the-clock support and exceptional service to boot. Add to that our Price Match Guarantee and a massive range of experiences and destinations to select from. It's our job to help you jet off on the vacation of a lifetime.
Will I save money on my Mesopotamia car rental if I combine it with hotels and flights?
Combining your car, hotel and flight into a Mesopotamia vacation package is the easiest way to land the best prices. Plus, having your own wheels gives you total freedom to find your way to all those big-name sights you can't wait to explore. Located 95 mi from Mesopotamia, White Tower of Thessaloniki is one attraction that should feature on your itinerary. Top up the tank and make a day trip of it.
Which airport is best for Mesopotamia?
Ioannina National Airport (IOA), located around 60 mi south of downtown Mesopotamia, is likely to be where you'll jet into. Your other options are Kastoria (KSO-Aristoteles) (7 mi away from central Mesopotamia) and Kozani (KZI-Filippos) (40 mi away from central Mesopotamia).
Where should I stay when visiting Mesopotamia?
The To Spiti tis Sofias is recommended by many visitors. Book soon to avoid missing out.

Photos of local treasures

Browse Mesopotamia vacation photos for more inspiration