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Top Mesopotamia hotels

To Spiti tis Sofias

To Spiti tis Sofias

Mesopotamia, Kastoria, Western Macedonia
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $78 total per night from Oct 13 to Oct 14
$78 total
Oct 13 - Oct 14
Total with taxes and fees
This guesthouse doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, a lobby fireplace, and a communal living room are also ...
Le meilleur de notre séjour
"Tout simplement le meilleur de notre voyage en Grèce. Simple mais tellement mieux qu'ailleurs. Accueil parfait, chambre confortable et petit déjeuner de roi. Je reviendrais à 100% si je passe dans le coin."

Reviewed on Aug 18, 2025

Opens in a new windowTo Spiti tis Sofias
Chloe Hotel

Chloe Hotel

3 out of 5
Antheon & Giasemion, Kastoria, Western Macedonia
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $123 total per night from Sep 30 to Oct 1
$123 total
Sep 30 - Oct 1
Total with taxes and fees
This Mediterranean hotel features ski-in/ski-out access, an attached winery, and a restaurant. Traveling on business? Take advantage of the business center, ...
"Romantic and special. Highly recommend. Kastoria is a rare find. This hotel is a great getaway."

Reviewed on Jun 26, 2025

Opens in a new windowChloe Hotel
Guest House Ilektra

Guest House Ilektra

Avgerinos, Voio
Fully refundableReserve now, pay when you stay
$52 nightly
The price is $61 total per night from Sep 30 to Oct 1
$61 total
Sep 30 - Oct 1
Total with taxes and fees
A restaurant and a bar/lounge are featured at this guesthouse. Guests will appreciate free perks like free self parking and WiFi in public areas. A terrace and ...
"Wonderful views, easy to find, spacious rooms, and great hospitality."

Reviewed on Aug 31, 2025

Opens in a new windowGuest House Ilektra
Calma Hotel & Spa

Calma Hotel & Spa

4 out of 5
3rd km Kastoria, Vitsi, Kastoria
A full-service spa and a gym are featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport ...
Cultural break
"Pleasant stay. Good amenities. Great staff."

Reviewed on Jul 16, 2025

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Opens in a new windowCalma Hotel & Spa
Limneon Resort & Spa

Limneon Resort & Spa

4 out of 5
4th km National Road Kastoria Athens, Kastoria
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $119 total per night from Oct 6 to Oct 7
$119 total
Oct 6 - Oct 7
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling for business? Take advantage of the free WiFi in ...
"Excellent!"

Reviewed on Sep 22, 2025

Opens in a new windowLimneon Resort & Spa
Esperos Palace Luxury & Spa Hotel

Esperos Palace Luxury & Spa Hotel

4 out of 5
Chloe Area, Kastoria, Western Macedonia
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $134 total per night from Sep 30 to Oct 1
$134 total
Sep 30 - Oct 1
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
"The hotel is beautiful, large room with balcony. Grate bathroom, comfortable, the dinner is good ,however the breakfast was amazing."

Reviewed on Sep 4, 2025

Opens in a new windowEsperos Palace Luxury & Spa Hotel
Hotel Anastassiou

Hotel Anastassiou

2 out of 5
1st km Highway Kastoria-Athens, Kastoria, Western Macedonia
Fully refundableReserve now, pay when you stay
$47 nightly
The price is $56 total per night from Oct 3 to Oct 4
$56 total
Oct 3 - Oct 4
Total with taxes and fees
Ski-in/ski-out access and a restaurant are featured at this smoke-free hotel. Enjoy the ski shuttle and onsite ski storage. Unwind with a drink at the bar/lounge ...
"Nice simple stay."

Reviewed on Mar 13, 2025

Opens in a new windowHotel Anastassiou
Hotel Kastoria

Hotel Kastoria

3 out of 5
NIKIS AVENUE 122, Kastoria
Free self parking is available and the hotel's multilingual staff can provide around-the-clock assistance. WiFi in public areas is free. A snack bar/deli, express ...
"Excellent position by the lake. Good room but old bathroom with a small shower. Variety at breakfast but expensive for 10 euros per person."

Reviewed on Oct 20, 2023

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Opens in a new windowHotel Kastoria
Anesis Hotel

Anesis Hotel

2 out of 5
Grammou 10, Kastoria
$57 nightly
The price is $67 total per night from Sep 30 to Oct 1
$67 total
Sep 30 - Oct 1
Total with taxes and fees
Free WiFi in public areas, a terrace, and luggage storage are available at this hotel. A safe deposit box and laundry facilities are also provided.
"It suited my purpose. Nothing fancy, but adequate. Only disappointed that when I arrived early all the way from America, they didn't allow me to check in for several hours when the place was empty, and they didn't offer to let me leave my heavy backpack with them while I waited. I had to walk around ..."

Reviewed on Jul 2, 2024

Opens in a new windowAnesis Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mesopotamia Hotel & Travel Guide\n

Are you planning to have some nights in Western Macedonia? Hoping to reserve somewhere to stay in the Mesopotamia area? Within an easy commute to the Mesopotamia CBD, travelers will find 2 modern lodging options.

Within a short drive of Mesopotamia, are the Hotel Nostos and Esperos Palace.

The Kyknos De Luxe Suites is located 5 miles (9 kilometers) from the central part of Mesopotamia. Or, alternatively, the Villa Del Lago is 7 miles (11 kilometers) away. An alternative option is to make a reservation at the Afkos Grammos Luxury Boutique Hotel or the Allahou.

After you've enjoyed Mesopotamia, make the trip to soak up the other cultural and scenic attractions of the Greek Mainland area. Greek Mainland is known for beaches, coastal plains and rivers. Interesting holiday attractions include castles. Common activities in this particular part of Greece include snowboarding and skiing.

The nearest accommodations in Western Macedonia include Kastoria and Aposkepos. Kastoria is 5 miles (8 kilometers) to the northeast of Mesopotamia, while Aposkepos is 6 miles (9 kilometers) to the northeast. Lodgings in Kastoria include the Hotel Anastassiou and Hotel Keletron. The Akropolis and Chloe Hotel are a selection of the Travelocity-registered accommodation options in Aposkepos.

After you have checked out the available hotel options in Mesopotamia, make sure you discover our Mesopotamia city page for the low-down on ways to spend your time in this area.

Frequently asked questions

What are the top kid-friendly hotels in Mesopotamia?
Take some of the challenges out of traveling with little ones by staying in a family-friendly Mesopotamia hotel. From special amenities to more services, these properties come with perks that'll make your visit plain sailing: Hotel Nostos will help make your break the most memorable one yet. It comes with a host of conveniences aimed at families, such as a cafe and express check-out services. Also look up Anesis Hotel. It offers front desk services, room service and plenty of opportunities to hang out as a family.
Where can I find cheap hotels in Mesopotamia?
At Travelocity you'll find really nice hotels in Mesopotamia at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Mesopotamia rather than in Mesopotamia. We may find you even better rates, too.
How do I find the best Mesopotamia hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Mesopotamia then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Mesopotamia?
The cheapest hotel in Mesopotamia is $56. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Mesopotamia?
There are 41 hotels in Mesopotamia on Travelocity.
What are the best hotels in Mesopotamia?
Mesopotamia has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Mesopotamia for you!
When is the best time to visit Mesopotamia?
If you want the joy of a fun-filled trip in peak season, visit Mesopotamia during May, August and September. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Mesopotamia?
Based on historic data is usually the cheapest month to visit Mesopotamia. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Mesopotamia?
There are multiple hotels in Mesopotamia that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Mesopotamia. We have plenty of kid-friendly hotels in Mesopotamia to choose from on Travelocity!
Why book a hotel in Mesopotamia through Travelocity?
Because we have the top hotels in Mesopotamia! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Mesopotamia on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Mesopotamia hotel reviews by fellow wanderers

Limneon Resort & Spa

Limneon Resort & Spa

5 out of 5
Posted 7 days ago
Travelocity Verified Review
"Excellent! "
A verified traveler stayed at Limneon Resort & Spa
Limneon Resort & Spa
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