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Top Mesopotamia hotels

To Spiti tis Sofias
Tout simplement le meilleur de notre voyage en Grèce. Simple mais tellement mieux qu'ailleurs. Accueil parfait, chambre confortable et petit déjeuner de roi. Je reviendrais à 100% si je passe dans le coin.
Reviewed on Aug 18, 2025

Chloe Hotel
Exceptional service, clean environment, superb breakfast and attentive staff.
Reviewed on Mar 27, 2026

Guest House Ilektra
Friendly and courteous hosts, great food and excellent service
Reviewed on Dec 29, 2025

Orologopoulos Mansion
Ideal accommodation in a tranquil area of the town, surrounded by character buildings. Several quality eating locations near by.
Reviewed on Oct 14, 2025

Limneon Resort & Spa
All staff superb both at reception and throughout the property. Rooms large and immaculate with all amenities. Property superb. Location peaceful and relaxing with balcony and view of the lake. Only 5 mins by car to Kastoria town. 8-10 Euros by taxi. Would have liked to stay longer if we had the ...
Reviewed on Apr 23, 2026

Esperos Palace Luxury & Spa Hotel
The hotel is beautiful, large room with balcony. Grate bathroom, comfortable, the dinner is good ,however the breakfast was amazing.
Reviewed on Sep 4, 2025

Hotel Kastoria
Excellent position by the lake. Good room but old bathroom with a small shower. Variety at breakfast but expensive for 10 euros per person.
Reviewed on Oct 20, 2023

Hotel Anastassiou

Le Marron
Mesopotamia Hotel & Travel Guide\n
Are you planning to have some nights in Western Macedonia? Hoping to reserve somewhere to stay in the Mesopotamia area? Within an easy commute to the Mesopotamia CBD, travelers will find 2 modern lodging options.
Within a short drive of Mesopotamia, are the Hotel Nostos and Esperos Palace.
The Kyknos De Luxe Suites is located 5 miles (9 kilometers) from the central part of Mesopotamia. Or, alternatively, the Villa Del Lago is 7 miles (11 kilometers) away. An alternative option is to make a reservation at the Afkos Grammos Luxury Boutique Hotel or the Allahou.
After you've enjoyed Mesopotamia, make the trip to soak up the other cultural and scenic attractions of the Greek Mainland area. Greek Mainland is known for beaches, coastal plains and rivers. Interesting holiday attractions include castles. Common activities in this particular part of Greece include snowboarding and skiing.
The nearest accommodations in Western Macedonia include Kastoria and Aposkepos. Kastoria is 5 miles (8 kilometers) to the northeast of Mesopotamia, while Aposkepos is 6 miles (9 kilometers) to the northeast. Lodgings in Kastoria include the Hotel Anastassiou and Hotel Keletron. The Akropolis and Chloe Hotel are a selection of the Travelocity-registered accommodation options in Aposkepos.
After you have checked out the available hotel options in Mesopotamia, make sure you discover our Mesopotamia city page for the low-down on ways to spend your time in this area.
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Limneon Resort & Spa
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