Book Hotels in Mesagne

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Mesagne hotels

Palazzo Sant'Anna Lecce

Palazzo Sant'Anna Lecce

5 out of 5
Vico del Pitaccio, 4/6 Lecce LE
Fully refundableReserve now, pay when you stay
$253 nightly
The price is $290 total per night from May 12 to May 13
$290 total
May 12 - May 13
Total with taxes and fees
A full-service spa and a hot tub are featured at this luxury hotel. Guests will appreciate free perks like buffet breakfast and WiFi in public areas. A terrace, ...
the hotel was hard to find but the staff were very helpful

Reviewed on Apr 24, 2026

Opens in a new windowPalazzo Sant'Anna Lecce
Arryvo

Arryvo

Via Adua 24 Lecce LE
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $125 total per night from May 5 to May 6
$125 total
May 5 - May 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. If you want to take your pet along, this pet-friendly property ...
Great location! The hotel is a club on the weekend so we were able to party with the locals. Fun vibe! Music is loud and playing until 2am but they provide ear plugs for anyone trying to get some sleep. Breakfast was great too! You order à la carte and it’s good quality food.

Reviewed on Apr 19, 2026

Opens in a new windowArryvo
Masseria Malvindi

Masseria Malvindi

5 out of 5
Strada Provinciale 74 Mesagne BR
Fully refundableReserve now, pay when you stay
$181 nightly
The price is $199 total per night from Apr 29 to Apr 30
$199 total
Apr 29 - Apr 30
Total with taxes and fees
This hotel features a restaurant, a seasonal outdoor pool, and a bar/lounge. Enjoy the a rooftop terrace and free perks like buffet breakfast and free self parking. ...
Great location, but a car is definitely needed. A very tranquil place, with only 14 rooms. Rooms and bathrooms are a good size and clean, however rather sparsely furnished. Staff were excellent, very helpful and offered a great service. The breakfast room was well stocked with a good variety of cold ...

Reviewed on Oct 5, 2025

Opens in a new windowMasseria Malvindi
Ostuni Palace Hotel Ristorante & SPA

Ostuni Palace Hotel Ristorante & SPA

4 out of 5
Corso Vittorio Emanuele 218 Ostuni BR
Fully refundableReserve now, pay when you stay
$177 nightly
The price is $202 total per night from May 10 to May 11
$202 total
May 10 - May 11
Total with taxes and fees
A full-service spa and a restaurant are featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
This property was absolutely beautiful. The staff was so accommodating and allowed us to check in much earlier than normal check in time. The dinner at the hotel was absolutely beautiful and delicious. I cannot say enough about the attentiveness of the staff! I highly recommend this hotel.

Reviewed on Apr 26, 2026

Opens in a new windowOstuni Palace Hotel Ristorante & SPA
Ostuni a Mare

Ostuni a Mare

4 out of 5
Rosa Marina - C.P. n. 82 Ostuni BR
$254 nightly
The price is $286 total per night from May 8 to May 9
$286 total
May 8 - May 9
Total with taxes and fees
A full-service spa, 2 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Enjoy beachfront dining and relax with sun loungers and beach ...
Beautiful clean facilities, with three pools and access to the beach Excellent breakfast options. Rooms were clean. Two restaurant options. It's an oasis in Puglia.

Reviewed on Sep 30, 2025

Opens in a new windowOstuni a Mare
Hotel Orientale

Hotel Orientale

4 out of 5
C.so Garibaldi, 40 Brindisi BR
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $141 total per night from May 20 to May 21
$141 total
May 20 - May 21
Total with taxes and fees
This hotel features a gym and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and train station pick-up ...
Antonella at Reception was so friendly , professional and helpful. She is a real asset toHotel Orientale.

Reviewed on Apr 19, 2026

Opens in a new windowHotel Orientale
Palazzo Virgilio

Palazzo Virgilio

4 out of 5
Corso Umberto I, 149 Brindisi BR
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $122 total per night from May 1 to May 2
$122 total
May 1 - May 2
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
We stayed only one night and really enjoyed it. The reception staff were very helpful with advice and things to see. We arrived very early in the day and we able to leave our bags while we spent the day exploring the area, before checking in later in the day. The room was excellent. Warm, quiet, ...

Reviewed on Apr 26, 2026

Opens in a new windowPalazzo Virgilio
Tenuta Moreno

Tenuta Moreno

4 out of 5
Contrada Moreno Mesagne BR
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $143 total per night from May 1 to May 2
$143 total
May 1 - May 2
Total with taxes and fees
This Beaux Arts hotel features a full-service spa, 2 outdoor tennis courts, and a restaurant. Traveling on business? Take advantage of the business center, free ...
Excellent, very nice place. Excellent room, very clean and comfortable. Stuff was very nice and welcoming.

Reviewed on Jan 6, 2026

Opens in a new windowTenuta Moreno
Grande Albergo Internazionale

Grande Albergo Internazionale

4 out of 5
Lungomare Regina Margherita Brindisi BR
Fully refundableReserve now, pay when you stay
$121 nightly
The price is $140 total per night from May 9 to May 10
$140 total
May 9 - May 10
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the 4 conference rooms, along with free WiFi in public areas. ...
The entrance to the hotel and the lobby area are elegant in an older style and very well maintained. We were greeted by Sarah at the front desk and she was just wonderful. The rooms were spacious and very clean, but they were also very tired. They needed some paint some tile work and a little bit ...

Reviewed on Apr 16, 2026

Opens in a new windowGrande Albergo Internazionale
Don't see what you're looking for?
See all available properties in Mesagne
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mesagne Hotel & Travel Guide\n

Want to explore Salento Peninsula? Want somewhere to lay your head? Travelocity features many great hotels and rooms. You can pick and choose from around 12 accommodations within a short distance of the center of Mesagne which are listed as part of Travelocity's easy-to-use booking portal.

Travelocity-listed places to stay within strolling distance of Mesagne's downtown area, are the Hotel Castello and B&B La Corte Degli Spada.

Mesagne features a limited range of budget lodgings; you will find the Hotel Castello situated 2 miles (3 kilometers) from the town center.

The Riva Marina Resort is positioned 14 miles (23 kilometers) from the town center of Mesagne. Another accommodation option is the Grand Hotel Masseria Santa Lucia, which is about 18 miles (29 kilometers) away. Alternatively, you might like to check out the rates and amenities at the Ostuni Rosa Marina Resort or the Relais La Sommità.

If you have the time, why not spread your wings and see the many other attractions to be found in Puglia during your stay in the region? Check out Puglia's ruins. Lovers of the great outdoors can also leave time to enjoy its rural landscapes, beaches, coastal plains and lakes. Sporty travelers might delve into mountain biking, mountain climbing and hiking in this part of Italy.

8 miles (12 kilometers) to the northeast of Mesagne, you can find Brindisi, where you can enjoy Museo Archeologico Provinciale Francesco Ribezzo and Monument to Italian Sailors. If you spend any time in Brindisi, be sure to check out the Santo Stefano Luxury Rooms and Palazzo Virgilio. Or, stay the night in Santa Caterina, 30 miles (47 kilometers) to the south of Mesagne, where you'll find the Santa Caterina Resort & Spa and Cala d'Aspide Resort. If you're staying in Santa Caterina, keep a day to explore the Santa Caterina Harbor and Torre dell'Alto.

While you are here why not spend some time enjoying thrills and spills with fellow lovers of sports at a community game. Stadio Via del Mare can be found 25 miles (39 kilometers) to the southeast of Mesagne. Wise travelers hoping to find a room in the area around the game should check out the Mantatelurè - Dimora Esclusiva or the Suite Hotel Santa Chiara.

Papola Casale Airport is a primary arrival point for flights, and can be found 11 miles (17 kilometers) from Mesagne's central precinct. Travelocity-listed hotels nearby include Grande Albergo Internazionale and Hotel Nettuno.

Frequently asked questions

What are the top kid-friendly hotels in Mesagne?
B&B La Grotta is a great choice for families vacationing in Mesagne. With top amenities like complimentary breakfast, this kid-friendly hotel makes guests of all ages feel at home.
Where can I find cheap hotels in Mesagne?
At Travelocity you'll find really nice hotels in Mesagne at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Mesagne rather than in Mesagne. We may find you even better rates, too.
How do I find the best Mesagne hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Mesagne then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Mesagne?
The cheapest hotel in Mesagne is $122. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Mesagne?
There are 7,384 hotels in Mesagne on Travelocity.
What are the best hotels in Mesagne?
Mesagne has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Mesagne for you!
When is the best time to visit Mesagne?
If you want the joy of a fun-filled trip in peak season, visit Mesagne during May, June and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Mesagne?
Based on historic data is usually the cheapest month to visit Mesagne. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Mesagne?
There are multiple hotels in Mesagne that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Mesagne. We have plenty of kid-friendly hotels in Mesagne to choose from on Travelocity!
Why book a hotel in Mesagne through Travelocity?
Because we have the top hotels in Mesagne! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Mesagne on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Mesagne hotel reviews by fellow wanderers

Ostuni Palace Hotel Ristorante & SPA

Ostuni Palace Hotel Ristorante & SPA

5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"This property was absolutely beautiful. The staff was so accommodating and allowed us to check in much earlier than normal check in time. The dinner at the hotel was absolutely beautiful and delicious. I cannot say enough about the attentiveness of the staff! I highly recommend this hotel. "
A verified traveler stayed at Ostuni Palace Hotel Ristorante & SPA
Ostuni Palace Hotel Ristorante & SPA

Explore More Ways to Travel with Travelocity