Book Hotels in Lyon, MS
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Top Lyon hotels

The Governors Mansion in Clarksdale Mississippi. A Step Back in Time
Clarksdale
An outdoor pool is featured at this villa, along with laundry facilities.
Great stay!
"We rented this house for my mother in law’s 80th birthday. The house was perfect! There was plenty of room for everyone to relax and socialize. This home is very comfortable and so beautiful! We thoroughly enjoyed our weekend!"
Reviewed on Jun 30, 2025

Only a mile from historic downtown Clarksdale!
Clarksdale
$202 nightly
The price is $216 total per night from Sep 30 to Oct 1
$216 total
Sep 30 - Oct 1
Total with taxes and fees
An outdoor pool is featured at this cottage, along with laundry facilities and barbecue grills.
"Amazing pool, perfect home, and location!"
Reviewed on Sep 8, 2025

Sunset Log Cabin
Clarksdale
$175 nightly
The price is $188 total per night from Oct 7 to Oct 8
$188 total
Oct 7 - Oct 8
Total with taxes and fees
This cabin features barbecue grills.
goin up to the country to relax
"Small cabin but perfect for us. the porch makes it a much larger space than it seems at first. The host was very attentive."
Reviewed on Jul 31, 2025

Travelers Hotel
212 3rd St, Clarksdale, MS
$159 nightly
The price is $174 total per night from Sep 30 to Oct 1
$174 total
Sep 30 - Oct 1
Total with taxes and fees
A bar/lounge and a fireplace in the lobby are featured at this hotel, along with free self parking. WiFi in public areas is free. Luggage storage is also ...
"Interesting concept. Self check in which worked fine for me. Hotel felt quiet even tho there were a number of people staying. Rooms won’t be to everyone’s taste but I liked and enjoyed my stay. One point of note: if you have luggage rooms on first floor don’t have lift access and the stairs are steep. ..."
Reviewed on Sep 28, 2025

Auberge Clarksdale Blues Hostel
164 Delta Ave, Clarksdale, MS
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $139 total per night from Sep 30 to Oct 1
$139 total
Sep 30 - Oct 1
Total with taxes and fees
Free WiFi in public areas, a communal living room, and express check-out are available at this hostel. Dry cleaning, luggage storage, and locker space are also ...
"I stay here every time I visit Clarkesdale. The bedscare clean and comfortable, rooms spacious and ckean, even a fan to use! I have never stayed in a hostel where the bathrooms are this ckean. They supply shampoo, deodorant, all you need."
Reviewed on Jul 26, 2025

The Sunflower Penthouse on the River in Clarksdale
Clarksdale
$200 nightly
The price is $214 total per night from Oct 5 to Oct 6
$214 total
Oct 5 - Oct 6
Total with taxes and fees
This vacation home features a garden, laundry facilities, and barbecue grills.
Still nice
"I like this spot. It's out of the way of all of the hustle and bustle, but still just a few minutes away from downtown and the main drag. There is a nice view of the Sunflower river and lots of space to roam around out back if you're adventurous.The seating in the living room needs to be cleaned. ..."
Reviewed on Aug 11, 2025

Hampton Inn Clarksdale
15000 New Africa Rd, Clarksdale, MS
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $130 total per night from Oct 6 to Oct 7
$130 total
Oct 6 - Oct 7
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"The staff was extremely knowledgeable and professional. Portia and Tia were terrific!"
Reviewed on Sep 26, 2025

Quality Inn
818 South State Street, Clarksdale, MS
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $96 total per night from Oct 12 to Oct 13
$96 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A computer station, laundry facilities, and free newspapers are also on ...
"Ants in the room and outdated bathroom,refrigerator and dirty microwave with the carpet dirty and stained"
Reviewed on Sep 8, 2025

Americas Best Value Inn & Suites Clarksdale
350 South State Street, Clarksdale, MS
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $83 total per night from Sep 30 to Oct 1
$83 total
Sep 30 - Oct 1
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Everything was straight"
Reviewed on Sep 27, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Lyon hotel reviews by fellow wanderers

Travelers Hotel
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Interesting concept. Self check in which worked fine for me. Hotel felt quiet even tho there were a number of people staying. Rooms won’t be to everyone’s taste but I liked and enjoyed my stay. One point of note: if you have luggage rooms on first floor don’t have lift access and the stairs are steep. Wouldn’t recommend if you have heavy luggage as I did. Hotel does have rooms on ground floor. Easy to walk around historic area and parking is right across the street. "
A verified traveler stayed at Travelers Hotel