Explore 10 Luxury Hotels in Downtown Santiago

Name: Hotel Vegas
Rating: 8

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Best Luxury Hotels in Downtown Santiago

The Singular Santiago

Merced 294 Santiago Region Metropolitana

Fully refundableReserve now, pay when you stay

$270 nightly

$270 total

Apr 14 - Apr 15

A full-service spa, 2 restaurants, and A 24-hour gym are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and free perks like cooked-to-order ...

9.6/10 Exceptional! (704 reviews)

The staff went above and beyond. The hotel is well located and had everything we need. The spa facilities were fantastic after a long travel day.

Reviewed on Mar 16, 2026

Matildas Hotel Boutique

Agustinas 2149 Santiago Region Metropolitana

Fully refundableReserve now, pay when you stay

$150 nightly

$150 total

Mar 27 - Mar 28

This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Traveling on business? Take advantage of the business center, ...

9.4/10 Exceptional! (281 reviews)

The hotel is so pretty that it is a gem In the old centro of Santiago. Nice breakfast and very nice staff specially Fernanda and Macarena.

Reviewed on Mar 13, 2026

Casa Bueras Boutique Hotel

Coronel Santiago Bueras 188 Santiago Region Metropolitana

Fully refundableReserve now, pay when you stay

$136 nightly

$136 total

Apr 14 - Apr 15

This hotel features an outdoor pool and a rooftop terrace. Families will appreciate the onsite laundry facilities and in-room childcare. Unwind with a drink ...

9.2/10 Wonderful! (537 reviews)

Staff was very friendly and helpful.

Reviewed on Mar 23, 2026

Altiplanico Bellas Artes

Santo Domingo 526 Santiago Region Metropolitana

Fully refundableReserve now, pay when you stay

This hotel features a bar/lounge, free WiFi in public areas, and a fireplace in the lobby. Free buffet breakfast is served. A computer station, luggage storage, ...

9.2/10 Wonderful! (584 reviews)

You could tell the rooms were old. Breakfast was extremely basic- far from amazing as the other reviews indicate. Take the 5 star reviews with a grain of salt. Location looks scary but a fairly good location.

Reviewed on Mar 22, 2026

Get rates

Hotel Plaza San Francisco

Alameda 816 Santiago Region Metropolitana

Fully refundableReserve now, pay when you stay

$116 nightly

$116 total

Apr 7 - Apr 8

A full-service spa, a gym, and a restaurant are all featured at this boutique hotel. Traveling on business? Take advantage of the business center, free WiFi ...

9.2/10 Wonderful! (1,000 reviews)

Excellent location and top notch service, breakfast, dinner and clean rooms and bathroom. This is a 4 star hotel for sure which I would surely recommend to anyone.

Reviewed on Mar 24, 2026

Lastarria Hotel & Aparts

José Victorino Lastarria, 43 Santiago Region Metropolitana

Fully refundableReserve now, pay when you stay

$71 nightly

$71 total

Mar 26 - Mar 27

This aparthotel features free WiFi in public areas, laundry facilities, and self parking. A terrace and a safe deposit box are also provided.

9.2/10 Wonderful! (288 reviews)

This property in the middle of everything and very conveniently located. If you need Wi-Fi, it’s very good. The bathroom is modern, the beds are comfortable. We didn’t get laundry service, but it’s available for a fee. The property is very clean and well lit. Please note that some properties are ...

Reviewed on Mar 21, 2026

Luciano K Hotel

Merced, 84 Santiago Región Metropolitana

Fully refundableReserve now, pay when you stay

$109 nightly

$109 total

Apr 7 - Apr 8

A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the laundry service ...

9/10 Wonderful! (727 reviews)

Reviewed on Mar 24, 2026

Hotel Vegas

Londres 49 Santiago Region Metropolitana

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, airport shuttle, and free internet ...

8/10 Very Good! (187 reviews)

This was a wonderful little boutique hotel on a walkable cobbled street. The staff was exceptional and the room was very comfortable and quiet. It was easily in walking distance to Centro and right by a subway stop. Wonderful little place to stay. Thank you!

Reviewed on Mar 30, 2023

Get rates

Don't see what you're looking for?

See all available properties in Downtown Santiago

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Downtown Santiago

Apartamentos Amélie

San Isidro 661 Santiago Región Metropolitana

Get rates

9.6/10 Exceptional! (5 reviews)

5 star hotels in Downtown Santiago

The Singular Santiago

Merced 294 Santiago Region Metropolitana

$270 nightly

$270 total

Apr 14 - Apr 15

9.6/10 Exceptional! (704 reviews)

Downtown Santiago Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Downtown Santiago luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Downtown Santiago to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Downtown Santiago will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Downtown Santiago, and plan your next opulent escape.

Downtown Santiago hotels essential information

Accommodation	901 hotels
Lowest Price	$54
Highest Price	$270
Popular hotels	The Singular Santiago, Casa Bueras Boutique Hotel, Luciano K Hotel, Altiplanico Bellas Artes, Matildas Hotel Boutique, Hotel Plaza San Francisco, Lastarria Hotel & Aparts, Hotel Vegas