Explore 32 Luxury Hotels in Tenderloin

Best Luxury Hotels in Tenderloin

Hotel Nikko San Francisco

222 Mason St, San Francisco, CA

Fully refundableReserve now, pay when you stay

A nightclub and a restaurant are featured at this luxury hotel. Enjoy the indoor pool and perks like free WiFi. You'll appreciate the gym, bar/lounge, and rooftop ...

9.2/10 Wonderful! (2,371 reviews)

"The room was clean and staff were very helpful. We enjoyed our stay and we will come back again. We didn’t use any of amenities and including the roof top we can’t say anything about it."

Reviewed on Jun 7, 2025

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The Clift Royal Sonesta San Francisco

495 Geary St, San Francisco, CA

Fully refundableReserve now, pay when you stay

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

9/10 Wonderful! (1,335 reviews)

"Welcoming and clean spacious rooms"

Reviewed on Jun 3, 2025

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Hotel Spero, Vignette Collection by IHG

405 Taylor St, San Francisco, CA

Fully refundable

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, 24-hour business center, ...

8.8/10 Excellent! (1,248 reviews)

A comfortable hotel

"A comfortable stay on floor 11. Staff were informative and polite. A kettle, and tea bags, were provided upon request. The hotel interior is unexpectedly lovely, given the exterior and the area it is situated in."

Reviewed on Jun 3, 2025

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Staypineapple, An Elegant Hotel, Union Square

580 Geary St, San Francisco, CA

Fully refundableReserve now, pay when you stay

This hotel features luggage storage, a safe deposit box, and concierge services. If you want to take your pet along, this pet-friendly property offers everything ...

8.6/10 Excellent! (1,003 reviews)

"Check-in was smooth and thanks to Yesha for making our check in experience exceptional. Hotel is location near a lot of restaurant. Will definitely come back"

Reviewed on Jun 4, 2025

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Handlery Union Square Hotel

351 Geary St, San Francisco, CA

Fully refundableReserve now, pay when you stay

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. ...

8.6/10 Excellent! (2,432 reviews)

"Good staffing. Room condition can be better."

Reviewed on Jun 7, 2025

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Hotel Bijou

111 Mason Street, San Francisco, CA

Fully refundableReserve now, pay when you stay

Free WiFi in public areas, luggage storage, and a safe deposit box are available at this hotel. A business center, locker space, and concierge services are also ...

7.4/10 Good! (767 reviews)

"The room was perfect. Bed extremely comfortable. Having the staff man the front door added to sense of security plus the keypad to the front door."

Reviewed on Jun 2, 2025

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Monarch Hotel

1015 Geary St, San Francisco, CA

Free WiFi in public areas, luggage storage, and a safe deposit box are available at this hotel. The front desk is staffed around-the-clock and concierge services ...

isapp

"Disappointed that they wouldn’t accommodate in any way due to covid. We would of wish to reschedule or have some options, instead of losing our money for something not our fault."

Reviewed on Aug 30, 2020

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Adante Hotel

610 Geary St, San Francisco, CA

This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Traveling on business? Take advantage of the laundry service ...

Cockroach

"It was all ok until my friend pointed out a very large cockroach dead on the bathroom floor"

Reviewed on Apr 26, 2020

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More 4 star hotels in Tenderloin

Grand Hyatt at SFO

55 S McDonnell Rd, San Francisco, CA

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9.6/10 Exceptional! (1,326 reviews)

5 star hotels in Tenderloin

Four Seasons Hotel San Francisco at Embarcadero

222 Sansome St, San Francisco, CA

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9.4/10 Exceptional! (1,001 reviews)

Tenderloin Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Tenderloin luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Tenderloin to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Tenderloin will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Tenderloin, and plan your next opulent escape.

Tenderloin hotels essential information

Accommodation	4,535 hotels
Lowest Price
Highest Price
Popular hotels	The Clift Royal Sonesta San Francisco, Hotel Spero, Vignette Collection by IHG, Hotel Nikko San Francisco, Staypineapple, An Elegant Hotel, Union Square, Handlery Union Square Hotel, Monarch Hotel, Hotel Bijou, Adante Hotel

Popular Luxury Stays in Tenderloin

Recent Tenderloin Hotel Reviews By Fellow Wanderers

Hotel Riu Plaza Fisherman's Wharf

5 out of 5

Posted 18 hours ago

Travelocity Verified Review

"We had an excellent stay. Proximity to Fisherman’s Wharf is what got us there but the rooms were great, free breakfast was a perk and proximity to public transportation was a win. Only change would be to have better cable channels or access to streaming networks (for those who have an account). That said, we only spent late nights and early mornings in the room so it was not a big miss."

A verified traveler stayed at Hotel Riu Plaza Fisherman's Wharf