South America Vacation Packages 2025 from $349

Search vacation packages deals in South America's top destinations

Rio de Janeiro

Vacations

South America flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Cassa Luxury Homes – Hotel Boutique

Zona Rosa

per person

Sep 6 - Sep 9

found 1 day ago

Roundtrip flight included

Fort Lauderdale (FLL) to Bogotá (BOG)

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and airport shuttle. Enjoy the gym and free perks like English breakfast and free self parking.

Apartasuite Edificio Monir

Usaquén

per person

Aug 1 - Aug 8

found 17 hours ago

Roundtrip flight included

San Juan (SJU) to Bogotá (BOG)

Free WiFi in public areas, a snack bar/deli, and a safe deposit box are available at this aparthotel. The front desk is staffed around-the-clock and laundry facilities are on offer.

Casa Republica Barranco Boutique Hotel

Barranco

Save 100% on your flight

per person

Sep 14 - Sep 19

found 21 hours ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to Lima (LIM)

This hotel features a rooftop terrace and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and airport drop-off service. Enjoy the free buffet breakfast each morning.

Swissôtel Lima

San Isidro

Save 100% on your flight

per person

Aug 24 - Aug 31

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Lima (LIM)

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. There's an indoor pool on site, and a 24-hour front desk and a coffee shop are also provided.

Illa Experience Hotel

Quito Historic Center

Save 100% on your flight

per person

Aug 28 - Sep 1

found 1 day ago

Roundtrip non-stop flight included

San Juan (SJU) to Quito (UIO)

This luxury hotel features an attached winery, a full-service spa, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and airport shuttle. Enjoy the outdoor pool and free local cuisine breakfast each morning.

Top South America hotels deals

Rochester Classic

Esmeralda 542, Buenos Aires, Capital Federal

Free Cancellation

Reserve now, pay when you stay

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This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. A coffee shop, a snack bar/deli, and a communal living room are also on offer.

Free WiFi

Restaurant

Regal Pacific Buenos Aires

25 De Mayo, 764, Buenos Aires, Capital Federal

Free Cancellation

Reserve now, pay when you stay

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A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and airport shuttle. Enjoy the seasonal outdoor pool and perks like free self parking.

Pool

Spa

Concorde Hotel

25 De Mayo 630, Buenos Aires, Capital Federal

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Free WiFi in public areas, dry cleaning, and luggage storage are available at this hotel. Multilingual staff at the 24-hour front desk can provide around-the-clock assistance.

Free WiFi

Air conditioning

Almacruz Hotel y Centro de Convenciones

San Antonio 65, Santiago, Region Metropolitana

Free Cancellation

Reserve now, pay when you stay

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This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Pool

Breakfast included

Argentina Tango Hotel

Suipacha 545, Buenos Aires, Capital Federal

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This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Traveling on business? Take advantage of the business center and free internet in public areas. Express check-in, luggage storage, and concierge services are also on offer.

Breakfast included

Free WiFi

Moreno Hotel Buenos Aires

Moreno 376, Buenos Aires, Capital Federal

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This hotel features a restaurant, a rooftop terrace, and a bar/lounge. WiFi in public areas is free. You'll appreciate the area shuttle, computer station, and dry cleaning.

Free WiFi

Restaurant

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Cine Teatro Cuiaba

You can get tickets for a performance at Cine Teatro Cuiaba during your stay in Cuiabá. Amble around the area's riverfront or experience its museums.

Bom Jesus de Cuiaba Church

Learn about the local history of Cuiabá when you take a trip to Bom Jesus de Cuiaba Church. Stroll along the riverfront or experience the area's museums.

Historical Museum of Mato Grosso

You can spend an afternoon exploring the galleries in Historical Museum of Mato Grosso during your travels in Cuiabá. Stroll along the riverfront or experience the area's museums.

Frequently asked questions

How much are vacation packages to South America?

Adventures are calling in South America, with Travelocity vacation packages starting as low as $349. Including hotels and flights, these sensational deals make it a cinch to see more of our wonderful planet.

Where can I get the best vacation package deals for South America?

You can lock in fantastic South America package deals with Travelocity. Pick and choose from 400 partner airlines and 1,000,000 properties worldwide and turn those vacation dreams into reality.

Why should I purchase my South America vacation bundle via Travelocity?

By booking your hotel, flights, activities and car rental all in one place, you'll save time and money. We have a professional customer service support team available round-the-clock, and you'll know that you'll always score the lowest price possible with our Price Match Guarantee. So, what's stopping you? Book that dream vacation today and get packing!

Can I save money on my South America car rental if I bundle it with my hotel or flight?

Bundling your bookings into a South America vacation package will certainly save you money. Combine a flight and car; a hotel, car and flight; or a car and hotel. You won't find a better way to discover the greater South America area than from behind the wheel of your own rental car. You can also add activities and experiences to your Travelocity package.

What is there to do in South America?

A diverse and inspiring destination, South America offers some terrific tourist attractions. Iguazu Falls and Obelisco are two of the most popular.