Explore top 2026 4 Star Hotels in San Gregorio

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Top San Gregorio 4 Star hotels

Grand Hyatt at SFO

Grand Hyatt at SFO

4 out of 5
55 S McDonnell Rd San Francisco CA
Fully refundableReserve now, pay when you stay
$309 nightly
The price is $345 total per night from Jan 18 to Jan 19
$345 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet ...
9.6/10 Exceptional! (1,473 reviews)
Room always clean and quiet. Great place to stay

Reviewed on Jan 15, 2026

Opens in a new windowGrand Hyatt at SFO
Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront

4 out of 5
600 Airport Boulevard Burlingame CA
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $130 total per night from Jan 24 to Jan 25
$130 total
Jan 24 - Jan 25
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.4/10 Very Good! (2,891 reviews)
Staff is very helpful especially Nina front desk , location next to the trail and nice restaurant on the water. Clean warm room and great view Highly recommended

Reviewed on Jan 12, 2026

Opens in a new windowHilton San Francisco Airport Bayfront
The Domain Hotel

The Domain Hotel

4 out of 5
1085 E El Camino Real Sunnyvale CA
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $121 total per night from Jan 17 to Jan 18
$121 total
Jan 17 - Jan 18
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
8.2/10 Very Good! (1,476 reviews)
Friendly staff and clean rooms

Reviewed on Jan 13, 2026

Opens in a new windowThe Domain Hotel
The Westin San Francisco Airport

The Westin San Francisco Airport

4 out of 5
1 Old Bayshore Hwy Millbrae CA
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $157 total per night from Jan 17 to Jan 18
$157 total
Jan 17 - Jan 18
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, express check-out, and free ...
8.8/10 Excellent! (1,991 reviews)
Nice place, great staff.

Reviewed on Jan 10, 2026

Opens in a new windowThe Westin San Francisco Airport
Hyatt Regency Santa Clara

Hyatt Regency Santa Clara

4 out of 5
5101 Great America Pkwy Santa Clara CA
Fully refundableReserve now, pay when you stay
$158 nightly
The price is $186 total per night from Jan 23 to Jan 24
$186 total
Jan 23 - Jan 24
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
9/10 Wonderful! (1,007 reviews)
Great view of the stadium!

Reviewed on Jan 14, 2026

Opens in a new windowHyatt Regency Santa Clara
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

4 out of 5
1333 Bayshore Hwy Burlingame CA
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $180 total per night from Jan 17 to Jan 18
$180 total
Jan 17 - Jan 18
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.8/10 Excellent! (1,340 reviews)
This hotel has been around for at least 40 years and continues to be a solid choice for a SF layover or business stay. Long gone are the days of Knuckles sports bar, but if you need a good night’s sleep and a professional hotel staff, this is the BEST hotel on hotel row in Burlingame.

Reviewed on Jan 8, 2026

Opens in a new windowHyatt Regency San Francisco Airport
Santa Clara Marriott

Santa Clara Marriott

4.5 out of 5
2700 Mission College Blvd Santa Clara CA
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $168 total per night from Jan 23 to Jan 24
$168 total
Jan 23 - Jan 24
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 26 conference rooms, 24-hour business ...
8.6/10 Excellent! (1,002 reviews)
Excellent Love Love

Reviewed on Jan 11, 2026

Opens in a new windowSanta Clara Marriott
DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport

4 out of 5
835 Airport Blvd Burlingame CA
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $120 total per night from Jan 23 to Jan 24
$120 total
Jan 23 - Jan 24
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.6/10 Excellent! (1,433 reviews)
Yes very courteous I appreciated the late checkout very much.

Reviewed on Jan 13, 2026

Opens in a new windowDoubleTree by Hilton San Francisco Airport
The Ameswell Hotel

The Ameswell Hotel

4.5 out of 5
800 Moffett Blvd Mountain View CA
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $170 total per night from Jan 16 to Jan 17
$170 total
Jan 16 - Jan 17
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 5 conference rooms, free WiFi in public areas, ...
9.6/10 Exceptional! (1,168 reviews)
The room, the food the ambience was great!!! I will definitely be back.

Reviewed on Jan 12, 2026

Opens in a new windowThe Ameswell Hotel
San Francisco Airport Marriott Waterfront

San Francisco Airport Marriott Waterfront

4 out of 5
1800 Old Bayshore Hwy Burlingame CA
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $169 total per night from Jan 24 to Jan 25
$169 total
Jan 24 - Jan 25
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.6/10 Excellent! (1,096 reviews)
Everything good

Reviewed on Jan 11, 2026

Opens in a new windowSan Francisco Airport Marriott Waterfront
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4 Star Hotels San Gregorio

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in San Gregorio 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in San Gregorio will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in San Gregorio, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent San Gregorio hotel reviews by fellow wanderers