Explore top 2026 4 Star Hotels in Historic Route 66

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Top Historic Route 66 4 Star hotels

Hyatt Regency O'Hare Chicago

Hyatt Regency O'Hare Chicago

4 out of 5
9300 Bryn Mawr Ave Rosemont IL
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $154 total per night from Jun 28 to Jun 29
$154 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
8.8/10 Excellent! (2,644 reviews)
"The door to the restroom kept getting jammed and wouldn’t close properly. Our room also had no WiFi… the staff couldn’t figure out why it wasn’t working."

Reviewed on Jun 10, 2026

Opens in a new windowHyatt Regency O'Hare Chicago
Fairmont Chicago at Millennium Park

Fairmont Chicago at Millennium Park

4.5 out of 5
200 North Columbus Drive Chicago IL
Fully refundableReserve now, pay when you stay
$224 nightly
The price is $266 total per night from Jul 7 to Jul 8
$266 total
Jul 7 - Jul 8
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities and in-room ...
8.8/10 Excellent! (2,187 reviews)
"Clean room, overall nice hotel, restaurant was nice for happy hour. Lobby smelled like an old lady and peltons in gym were broken. Overall lovely stay."

Reviewed on Jun 9, 2026

Opens in a new windowFairmont Chicago at Millennium Park
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $179 total per night from Jun 14 to Jun 15
$179 total
Jun 14 - Jun 15
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
8.6/10 Excellent! (4,098 reviews)
"Good location. Nice lobby with a variety of food options."

Reviewed on Jun 10, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
InterContinental Chicago Magnificent Mile by IHG

InterContinental Chicago Magnificent Mile by IHG

4.5 out of 5
505 N Michigan Ave Chicago IL
Fully refundable
$224 nightly
The price is $267 total per night from Jul 1 to Jul 2
$267 total
Jul 1 - Jul 2
Total with taxes and fees
This luxury hotel includes 2 restaurants, an indoor pool, and a gym. Enjoy the sauna and perks like free WiFi. A bar/lounge, a 24-hour front desk, and a coffee ...
9.2/10 Wonderful! (3,090 reviews)
"Clean and spacious room, staff was great. Great location easy to walk to other activities and restaurants."

Reviewed on Jun 9, 2026

Opens in a new windowInterContinental Chicago Magnificent Mile by IHG
Embassy Suites by Hilton Chicago Downtown River North

Embassy Suites by Hilton Chicago Downtown River North

4 out of 5
600 N State St Chicago IL
Fully refundableReserve now, pay when you stay
$189 nightly
The price is $224 total per night from Jul 5 to Jul 6
$224 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the gym and free full breakfast each morning. Valet parking, a business center, and ...
8.6/10 Excellent! (5,962 reviews)
"Great breakfast"

Reviewed on Jun 10, 2026

Opens in a new windowEmbassy Suites by Hilton Chicago Downtown River North
The Chicago Hotel Collection Ambassador Gold Coast

The Chicago Hotel Collection Ambassador Gold Coast

4 out of 5
1301 N State Pkwy Chicago IL
Fully refundableReserve now, pay when you stay
$154 nightly
The price is $183 total per night from Jul 6 to Jul 7
$183 total
Jul 6 - Jul 7
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, ...
8.2/10 Very Good! (1,580 reviews)
"The restaurant was not open other than mediocre breakfast buffet. They only clean the rooms every 3rd day. The lobby bar was slow to open in the afternoon."

Reviewed on Jun 10, 2026

Opens in a new windowThe Chicago Hotel Collection Ambassador Gold Coast
L7 Chicago by LOTTE

L7 Chicago by LOTTE

4.5 out of 5
225 N Wabash Ave Chicago IL
$332 nightly
The price is $395 total per night from Jul 1 to Jul 2
$395 total
Jul 1 - Jul 2
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. WiFi in public areas is free. Valet parking, a coffee shop, and a lobby fireplace are also ...
9.6/10 Exceptional! (4,158 reviews)
"The hotel is very good in general (clean, friendly and professional staff, quiet etc.). However, the location is unbeatable. Literary, it is a couple mins from river, right on the edge of loop and north downtown area, about 10-15 min walking distance from museums, 30 min walking distance from Navy ..."

Reviewed on Jun 10, 2026

Opens in a new windowL7 Chicago by LOTTE
Hotel Riu Plaza Chicago

Hotel Riu Plaza Chicago

4 out of 5
150 East Ontario Street Chicago IL
$176 nightly
The price is $209 total per night from Jun 30 to Jul 1
$209 total
Jun 30 - Jul 1
Total with taxes and fees
This hotel features 2 bars/lounges and a 24-hour gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy a meal from the restaurant ...
9.4/10 Exceptional! (4,405 reviews)
"Great breakfast buffet included with stay"

Reviewed on Jun 10, 2026

Opens in a new windowHotel Riu Plaza Chicago
Hotel Felix River North/Magnificent Mile

Hotel Felix River North/Magnificent Mile

4 out of 5
111 W Huron St Chicago IL
Fully refundableReserve now, pay when you stay
$177 nightly
The price is $210 total per night from Jun 30 to Jul 1
$210 total
Jun 30 - Jul 1
Total with taxes and fees
This hotel features a 24-hour gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet ...
8.2/10 Very Good! (2,779 reviews)
"Great experience!"

Reviewed on Jun 10, 2026

Opens in a new windowHotel Felix River North/Magnificent Mile
The Chicago Hotel Collection - Magnificent Mile

The Chicago Hotel Collection - Magnificent Mile

4 out of 5
166 E Superior Street Chicago IL
$162 nightly
The price is $192 total per night from Jul 1 to Jul 2
$192 total
Jul 1 - Jul 2
Total with taxes and fees
This boutique hotel's 2 restaurants, 2 bars/lounges, and 24-hour gym are some of the featured amenities. Business travelers can take advantage of the free WiFi ...
7.8/10 Good! (1,551 reviews)
"Enjoyed our stay"

Reviewed on Jun 10, 2026

Opens in a new windowThe Chicago Hotel Collection - Magnificent Mile
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4 Star Hotels Historic Route 66

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Historic Route 66 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Historic Route 66 will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Historic Route 66, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Historic Route 66 hotel reviews by fellow wanderers

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