Explore top 2025 4 Star Hotels in Ortygia

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Top Ortygia 4 Star hotels

Algila' Ortigia Charme Hotel

Via Vittorio Veneto 93, Syracuse, SR

Fully refundableReserve now, pay when you stay

This hotel features a restaurant and 2 bars/lounges. Families will appreciate complimentary bicycles, kid-friendly dining, and in-room childcare. Guests will ...

9.4/10 Exceptional! (882 reviews)

We really enjoyed this property. The buildings are ancient, but completely renovated and clean. Bathrooms are new, beds are comfortable with good linens. Breakfasts are excellent with many choices.

Reviewed on Oct 10, 2025

Get rates

Charme Hotel Henry's House

Via del Castello Maniace n. 68, Syracuse, SR

Fully refundableReserve now, pay when you stay

$280 nightly

$320 total

Nov 3 - Nov 4

Total with taxes and fees

This hotel features a rooftop terrace and a bar/lounge. Guests will appreciate free perks like continental breakfast and WiFi in public areas. Valet parking, ...

9.4/10 Exceptional! (316 reviews)

Excellent all around .. a gem

Reviewed on Oct 20, 2025

Palazzo Artemide - VRetreats

Via Roma 66, Syracuse, SR

Fully refundable

$213 nightly

$246 total

Nov 18 - Nov 19

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a coffee shop, and limo/town car service are also ...

9.4/10 Exceptional! (649 reviews)

Very courteous staff. Excellent location close to everything. Room was modern and clean. Highly recommend.

Reviewed on Oct 22, 2025

Hotel Livingston Siracusa

Via Nizza, 17, Syracuse, SR

Fully refundableReserve now, pay when you stay

A bar/lounge and a 24-hour front desk are featured at this hotel, along with valet parking. Guests will appreciate free perks like full breakfast and WiFi in ...

8.8/10 Excellent! (254 reviews)

Wonderful place right on the ocean you can literally walk to anything

Reviewed on Oct 4, 2025

Get rates

Ortigia Royal Suite

Via Alagona, 87/89, Ortigia, Syracuse, SR

A rooftop terrace, valet parking, and laundry facilities are featured at this residence. Guests will appreciate free perks like full breakfast and WiFi in public ...

Amazing host. He couldn’t do enough for us during our stay and replied almost instantly to my messages. Suite was clean and tidy. Single bed is in a separate room with a door. Suite can be made incredibly dark so you can have a good lie in! One small improvement could be more pressure in the ...

Reviewed on Aug 23, 2024

Get rates

Don't see what you're looking for?

See all available properties in Ortygia

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Ortygia

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Ortygia 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Ortygia will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Ortygia, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.