Explore top 2026 5 Star Hotels in Syracuse

Name: Wellness & Spa Hotel Principe di Fitalia
Rating: 9.6

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Top Syracuse 5 Star hotels

Grand Hotel Ortigia Siracusa

Viale Mazzini, 12 Syracuse SR

Fully refundableReserve now, pay when you stay

$340 nightly

$386 total

Jun 2 - Jun 3

Total with taxes and fees

This hotel features a restaurant, a rooftop terrace, and a bar/lounge. Take the beach shuttle and relax with sun loungers and beach umbrellas. WiFi in public ...

9/10 Wonderful! (594 reviews)

"This is a fabulous old style hotel brought up to date in a really good location for Ortigia. The rooftop restaurant and terrace have a beautiful view and breakfast has a very large choice and is very good. The staff are extremely attentive and all seem to have the freedom to chat to guests like human ..."

Reviewed on May 26, 2026

Ortea Palace Hotel, Sicily, Autograph Collection

Via Riva Nazario Sauro Syracuse SR

Fully refundableReserve now, pay when you stay

$509 nightly

$571 total

Jun 1 - Jun 2

Total with taxes and fees

A full-service spa, 2 restaurants, and a 24-hour gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

9.4/10 Exceptional! (264 reviews)

"The in-room WiFi wasn’t working and they said it wouldn’t be working. That the in-room was a third party and they had no control!! Out coffee table was about to fall apart. Maintenance did come to try and save it but they couldn’t. So we had to live with it for the duration of our stay. The bar was ..."

Reviewed on May 6, 2026

Caportigia Boutique Hotel

Viale Montedoro 76 Syracuse SR

Fully refundableReserve now, pay when you stay

$230 nightly

$265 total

Jul 1 - Jul 2

Total with taxes and fees

This hotel features a restaurant, a hot tub, and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. You'll appreciate ...

9.4/10 Exceptional! (278 reviews)

"Everything was really good at this hotel. The location and cleanliness were great to including the staff. The only thing I would say is that if you did need room service, they charge €10 which seemed punitive."

Reviewed on May 28, 2026

Dimora Caiammari Luxury Hotel & Spa

Via Daniele Impellizzeri Syracuse SR

$287 nightly

$327 total

Jun 9 - Jun 10

Total with taxes and fees

This luxury hotel features a full-service spa, 2 outdoor pools, and a restaurant. There's fun for all ages with a children's pool and a playground, and families ...

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Passeggio Adorno 10/12 Syracuse SR

$581 nightly

$650 total

Jun 4 - Jun 5

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public areas, ...

9.4/10 Exceptional! (81 reviews)

Reviewed on May 23, 2026

Minareto

Via del Faro Massolivieri 26 Syracuse SR

Fully refundableReserve now, pay when you stay

$378 nightly

$428 total

Jun 3 - Jun 4

Total with taxes and fees

This luxury hotel features a private beach, a full-service spa, and 2 restaurants. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Families ...

8.8/10 Excellent! (269 reviews)

"Beyond the hotel’s stunning and breathtaking views, the customer service was truly exceptional—both attentive and highly responsive. I would easily rate them 120%! I absolutely loved the jacuzzi and its location, which made the experience even more special. Both of the rocky and sandy beaches were ..."

Reviewed on Apr 22, 2026

Wellness & Spa Hotel Principe di Fitalia

Traversa Tonnara di Terrauzza 51 Syracuse SR

An attached winery, a full-service spa, and 2 outdoor pools are all featured at this luxury hotel. There's fun for all ages with a children's club and a children's ...

9.6/10 Exceptional! (94 reviews)

"This was such a wonderful stay! Spotless beautiful property with friendly staff and delicious breakfast!!! Very impressed!"

Reviewed on Oct 19, 2025

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Syracuse Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Syracuse to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Syracuse 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Syracuse before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Syracuse hotel reviews by fellow wanderers

Lanterne Magiche Ortigia

5 out of 5

Posted 1 day ago

Travelocity Verified Review

"Hébergement spacieux et très bien placé pour profiter d'Ortygie en journée comme en soirée, personnel très courtois et agréable."

A verified traveler stayed at Lanterne Magiche Ortigia

Grand Hotel Ortigia Siracusa

5 out of 5

Posted 6 days ago

Travelocity Verified Review

A verified traveler stayed at Grand Hotel Ortigia Siracusa

Grand Hotel Des Ètrangers - The Leading Hotels of the World

4 out of 5

Posted 8 days ago

Travelocity Verified Review

"We were a bit disappointed with our stay at Grand Hotel des Étrangers. While the hotel has been beautifully renovated and is in very good condition, it felt more like a generic luxury hotel and lacked the Sicilian character we were hoping for. The breakfast room also felt somewhat “hotel-like,” although the breakfast itself was delicious. The staff were consistently friendly and helpful, and we especially loved the pool, which was heated to a very comfortable 28°C. The spa was also lovely, although it was frustrating that we were only told about the beautiful recovery room after our treatments were finished and we had already changed. The outdoor rooftop bar was lovely as well with comfy couches and a great view. There were a few downsides that made the stay feel overpriced for what we received. Parking at the hotel costs €50 per day, but we found the public Talete lot nearby for only €15. Our room was quite basic and very small, facing an alley where there was constant noise from dumpsters being emptied. For roughly $1,000 per night, we expected much more. Another issue was the loud music from the beach club on the ground floor, especially in the late afternoon and evening. We’re also not convinced it’s worth paying a premium for a sea-view upgrade, as the views over Siracusa are pleasant but not particularly spectacular. Overall, the hotel has some strong points, but for the price, we expected a more special and authentic experience."

A verified traveler stayed at Grand Hotel Des Ètrangers - The Leading Hotels of the World