St. James Vacation Packages 2026 from $327

St. James flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Baymont by Wyndham Kirksville University Area

$327

per person

Oct 8 - Oct 10

found 15 hours ago

Roundtrip flight included

New York (NYC) to Columbia (COU)

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business center and onsite conference space. A 24-hour gym and a safe deposit box are also provided.

Holiday Inn Express & Suites Kirksville - University Area by IHG

$396

per person

Oct 8 - Oct 10

found 15 hours ago

Roundtrip flight included

New York (NYC) to Columbia (COU)

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Super 8 by Wyndham Kirksville-University Area

$334

per person

Oct 8 - Oct 10

found 15 hours ago

Roundtrip flight included

New York (NYC) to Columbia (COU)

This hotel features free WiFi in public areas, laundry facilities, and free parking. Guests will appreciate freebies like buffet breakfast and free self parking. Staff at the 24-hour front desk can provide around-the-clock assistance.

Top St. James hotels deals

Greenlight Inn & Suites

110 N Outer Rd St. James MO

Free Cancellation

Reserve now, pay when you stay

$68 nightly

$77 total

Aug 17 - Aug 18

Total with taxes and fees

This smoke-free hotel includes 6 restaurants, an indoor pool, and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like self-serve breakfast and free self parking.

Economy Inn

102 N Outer Rd St. James MO

Free Cancellation

Reserve now, pay when you stay

$50 nightly

$57 total

Aug 15 - Aug 16

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock assistance.

Cozy Cottage on Historic Route 66, minutes away from Wineries & Restaurants.

Saint James MO

$141 nightly

$151 total

Aug 24 - Aug 25

Total with taxes and fees

This cottage features laundry facilities.

The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James

Saint James MO

$167 nightly

$176 total

Sep 8 - Sep 9

Total with taxes and fees

This vacation home features a garden, laundry facilities, and barbecue grills.

The James Stay on Historic Route 66 • minutes away from Wineries & Restaurants

Saint James MO

$137 nightly

$147 total

Aug 17 - Aug 18

Total with taxes and fees

This vacation home features laundry facilities.

Getaway Cabin next door to Maramec Spring Park & Meramec River Trophy Trout

St James MO

Get rates

This cabin featured laundry facilities and barbecue grills.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular St. James attractions

Maramec Spring Park

9.4/10 (55 reviews)

Explore the great outdoors at Maramec Spring Park, a lovely green space in St. James. While in this family-friendly area, you can enjoy the wineries.

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Frequently asked questions

How much are vacation packages to St. James?

Travelocity offers hotel and flight packages from as low as $327. With such great bargains, you'll be saying hello to St. James before too long.

How long should my St. James vacation be?

Most travelers spend roughly 2 nights in St. James, but how long you stay is totally up to you. If you intend to explore all the wonderful things this place has waiting for you, why not hang around for a little bit longer?

Where can I get the best vacation package deals for St. James?

Whatever your travel style, Travelocity can help you get the perfect St. James package deal. All you have to do is pick and choose between our 400 airlines and 1,000,000 properties across the globe.

Why should I purchase my St. James vacation bundle with Travelocity?

Because you'll never wander alone if you book with us, and we offer 24/7 support and top-notch service to boot. Add to that our Price Match Guarantee and countless experiences to choose from. We're here to make your daydreams a reality.

Can I save money on my St. James car rental if I bundle it with my hotel or flight?

Certainly — combine your car, flight and hotel into a St. James vacation package and you'll save a handsome sum. With so much to see and do in St. James, having your own set of wheels will make it easy to explore. Once you've buckled up, put the stereo on and cruise toward Busch Stadium, a famous sight roughly 90 mi from St. James.

Which airport is best for St. James?

Waynesville Regional Airport (TBN) is the main airport for those flying to St. James. Once you step off the plane, you'll find yourself 35 mi southwest of the downtown area.

What is there to do in St. James?

While getting off the beaten track is rewarding, you shouldn't ignore the well-known sights that make a place famous. Maramec Spring Park and Meramec Vineyards are just two of them in St. James.

Where should I stay when visiting St. James?

The Economy Inn is recommended by many visitors. Book now to avoid missing out.