Book Hotels in St. Helena, NE
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Top St. Helena hotels

Fairfield Inn & Suites by Marriott Yankton
508 WEST 21ST STREET Yankton SD
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $117 total per night from Mar 8 to Mar 9
$117 total
Mar 8 - Mar 9
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public areas. ...
The property was well lit and in excellent condition. The staff was very helpful!
Reviewed on Feb 23, 2026

Comfort Inn Yankton SD
611 W 23rd Street Yankton SD
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $109 total per night from Mar 26 to Mar 27
$109 total
Mar 26 - Mar 27
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies ...
Everything was good. Staff was very friendly.
Reviewed on Feb 21, 2026

Lewis and Clark Resort
43496 Shore Drive Yankton SD
$84 nightly
The price is $89 total per night from Mar 1 to Mar 2
$89 total
Mar 1 - Mar 2
Total with taxes and fees
A marina and a restaurant are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
Clean room. Beautiful location. Comfortable stay
Reviewed on Feb 21, 2026

Best Western Vermillion Inn
701 W Cherry St Vermillion SD
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $106 total per night from Mar 1 to Mar 2
$106 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. There's a sauna on site, and a 24-hour ...
Room was clean, staff was friendly, quiet environment
Reviewed on Feb 24, 2026

Holiday Inn Express Hotel & Suites Vermillion by IHG
1200 N Dakota St Vermillion SD
$99 nightly
The price is $110 total per night from Mar 5 to Mar 6
$110 total
Mar 5 - Mar 6
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business center, ...
All ok except in the middle of renovations do a not messy in parts
Reviewed on Feb 27, 2026

Best Western Kelly Inn
1607 E Highway 50 Yankton SD
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $106 total per night from Mar 1 to Mar 2
$106 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Everything was pretty good, but the 2nd night was crazy. We didn’t get to bed until midnight, kids were running in the hallway and screaming.
Reviewed on Feb 22, 2026

Red Roof Inn Vermillion - U of South Dakota
1208 E Cherry St Vermillion SD
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $77 total per night from Mar 5 to Mar 6
$77 total
Mar 5 - Mar 6
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like full breakfast and WiFi in public areas. A snack ...
Bathroom needs to be updated. Have stayed in several rooms now and all need plumbing attention in the showers.
Reviewed on Feb 23, 2026

Econo Lodge Inn & Suites
2410 Broadway Ave Yankton SD
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $71 total per night from Mar 8 to Mar 9
$71 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Pool room was chilly
Reviewed on Feb 22, 2026

Holiday Inn Express & Suites Yankton by IHG
2607 Broadway Ave Yankton SD
Fully refundable
$106 nightly
The price is $117 total per night from Mar 4 to Mar 5
$117 total
Mar 4 - Mar 5
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent St. Helena hotel reviews by fellow wanderers

Comfort Inn Yankton SD
5 out of 5
Posted 6 days ago
Travelocity Verified Review
"Everything was good. Staff was very friendly. "
A verified traveler stayed at Comfort Inn Yankton SD
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