Book Hotels in St. Helena, NE
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Top St. Helena hotels

Fairfield Inn & Suites by Marriott Yankton
508 WEST 21ST STREET Yankton SD
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $142 total per night from Jun 28 to Jun 29
$142 total
Jun 28 - Jun 29
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public areas. ...
"Staff"
Reviewed on May 17, 2026

Holiday Inn Express & Suites Yankton by IHG
2607 Broadway Ave Yankton SD
Fully refundable
$110 nightly
The price is $122 total per night from Jun 28 to Jun 29
$122 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"Good"
Reviewed on May 31, 2026

Comfort Inn Yankton SD
611 W 23rd Street Yankton SD
Fully refundable
$101 nightly
The price is $112 total per night from Jun 23 to Jun 24
$112 total
Jun 23 - Jun 24
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies ...
"Nice room and great breakfast. They even had lemon water and cookies"
Reviewed on May 27, 2026

Lewis and Clark Resort
43496 Shore Drive Yankton SD
$124 nightly
The price is $131 total per night from Jun 4 to Jun 5
$131 total
Jun 4 - Jun 5
Total with taxes and fees
A marina and a restaurant are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
"Staff very friendly throughout entire stay."
Reviewed on May 25, 2026

Best Western Vermillion Inn
701 W Cherry St Vermillion SD
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $106 total per night from Jun 16 to Jun 17
$106 total
Jun 16 - Jun 17
Total with taxes and fees
This hotel features an indoor pool and a gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. There's a sauna on site, and a 24-hour ...
"A great stop. They have a nice pool area with sauna and hot tub. They also accommodated a late check out when we needed a car repair done! So friendly"
Reviewed on Jun 1, 2026

Best Western Kelly Inn
1607 E Highway 50 Yankton SD
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $113 total per night from Jun 14 to Jun 15
$113 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Kind staff, pet friendly, easy check in check out, breakfast was meh but the coffee was good and all I care about!"
Reviewed on May 14, 2026

Super 8 by Wyndham Yankton
1603 East Highway 50 Yankton SD
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $94 total per night from Jun 7 to Jun 8
$94 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
"Helpful staff and clean, but A/C filled the room full of noise trying to keep it cool."
Reviewed on May 29, 2026

Econo Lodge Inn & Suites Yankton
2410 Broadway Ave Yankton SD
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $85 total per night from Jun 9 to Jun 10
$85 total
Jun 9 - Jun 10
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"The hotel was smelly and dirty."
Reviewed on May 30, 2026

Prairie Inn
916 N Dakota Street Vermillion SD
$80 nightly
The price is $87 total per night from Jun 6 to Jun 7
$87 total
Jun 6 - Jun 7
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Guests will appreciate free perks like free self parking and WiFi in public areas. The front desk is ...
"It was a good place to stay for the night for the price."
Reviewed on May 27, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent St. Helena hotel reviews by fellow wanderers

Red Roof Inn Vermillion - U of South Dakota
5 out of 5
Posted 5 hours ago
Travelocity Verified Review
"I needed an iron and the staff promptly brought me an iron & ironing board. They were very friendly and helpful!"
A verified traveler stayed at Red Roof Inn Vermillion - U of South Dakota
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