Book Hotels in St. Helena, NE
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top St. Helena hotels

Fairfield Inn & Suites by Marriott Yankton
508 WEST 21ST STREET, Yankton, SD
Fully refundableReserve now, pay when you stay
$154 nightly
The price is $169 total per night from Oct 5 to Oct 6
$169 total
Oct 5 - Oct 6
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public areas. ...
"The front desk stuff was nice ! They greeted you when you came in and were very helpful. At same time breakfast was very poor there was almost nothing to eat. The hotel was brand new and looked good and clean. Outside hotel different story it’s build on Parking lot of a shopping center which was ..."
Reviewed on Sep 27, 2025

Comfort Inn Yankton SD
611 W 23rd Street, Yankton, SD
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $112 total per night from Oct 7 to Oct 8
$112 total
Oct 7 - Oct 8
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies ...
Great hotel
"Clean room, great breakfast, great coffee."
Reviewed on Sep 28, 2025

Lewis and Clark Resort
43496 Shore Drive, Yankton, SD
$98 nightly
The price is $104 total per night from Oct 30 to Oct 31
$104 total
Oct 30 - Oct 31
Total with taxes and fees
A marina and a restaurant are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
"Enjoyed outdoor"
Reviewed on Sep 13, 2025

Best Western Vermillion Inn
701 W Cherry St, Vermillion, SD
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $106 total per night from Oct 12 to Oct 13
$106 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. There's a sauna on site, and a 24-hour ...
"All the staff were excellent!"
Reviewed on Sep 16, 2025

Holiday Inn Express Hotel & Suites Vermillion by IHG
1200 N Dakota St, Vermillion, SD
$137 nightly
The price is $151 total per night from Oct 11 to Oct 12
$151 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business center, ...
"Cleanliness was important. A great nights sleep."
Reviewed on Sep 6, 2025

Red Roof Inn Vermillion - U of South Dakota
1208 E Cherry St, Vermillion, SD
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $99 total per night from Sep 30 to Oct 1
$99 total
Sep 30 - Oct 1
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. WiFi in public areas is free. A snack bar/deli is provided and the front desk is staffed ...
"I like the size of the rooms and very clean. They could use some better pillows."
Reviewed on Sep 22, 2025

Best Western Kelly Inn
1607 E Highway 50, Yankton, SD
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $117 total per night from Oct 5 to Oct 6
$117 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Breakfast was not very good."
Reviewed on Sep 15, 2025

Yankton Inn
1603 East Highway 50, Yankton, SD
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $94 total per night from Sep 30 to Oct 1
$94 total
Sep 30 - Oct 1
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
"It is an older building hallways do not have air conditioning in hallways, bed was comfortable, nice breakfasts with protein's."
Reviewed on Sep 23, 2025

Econo Lodge Inn & Suites
2410 Broadway Ave, Yankton, SD
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $90 total per night from Oct 5 to Oct 6
$90 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Good value"
Reviewed on Sep 22, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent St. Helena hotel reviews by fellow wanderers

Comfort Inn Yankton SD
5 out of 5
Posted 23 hours ago
Travelocity Verified Review
"Clean room, great breakfast, great coffee. "
A verified traveler stayed at Comfort Inn Yankton SD
Explore More Ways to Travel with Travelocity
Explore More Ways to Travel with Travelocity
- Hotels near Ashfall Fossil Beds State Historical Park
- Winnebago Hotels
- Dakota City Hotels
- Motels in Dakota City
- Cabins in Hartington
- Hotels with Bar in Hartington
- Pet Friendly Hotels in Hartington
- Hotel Wedding Venues Hotels in Hartington
- Hartington Hotels
- Convention Center Hotels in Wayne
- Hotels with Bar in Wayne
- Spa Resorts & in Wayne
- Wayne Hotels
- Motels in Wayne
- Royal Hotels
- Hotels near Ponca State Park
- 4 Star Hotels in Bloomfield
- 5 Star Hotels in Bloomfield
- Cottages in Bloomfield
- Bloomfield Hotels
- Thurston Hotels
- Casino Resorts & in South Sioux City
- Kid Friendly Hotels in South Sioux City
- Hotels with Hot Tubs in South Sioux City
- Hotels with an Indoor Pool in South Sioux City
- Luxury Hotels in South Sioux City
- Pet Friendly Hotels in South Sioux City
- Romantic Getaways & Hotels in South Sioux City
- Hotel Wedding Venues Hotels in South Sioux City
- South Sioux City Hotels
- Motels in South Sioux City
- Vacation Homes in South Sioux City
- Farmstay in Coleridge
- Coleridge Hotels
- Vacation Homes in Coleridge
- Apartments in Norfolk
- Arcade Hotels in Norfolk
- Hotels with Hot Tubs in Norfolk
- Hotels with an Indoor Pool in Norfolk
- Luxury Hotels in Norfolk
- Pet Friendly Hotels in Norfolk
- Spa Resorts & in Norfolk
- Norfolk Hotels
- Motels in Norfolk
- Vacation Homes in Norfolk
- 5 Star Hotels in Niobrara
- Cottages in Niobrara
- Niobrara Hotels
- Lodges in Niobrara
- Vacation Homes in Niobrara
- Hotels near Wayne County Courthouse
- 5 Star Hotels in Verdigre
- Verdigre Hotels
- B&B in Newcastle
- Guest Houses in Newcastle
- Newcastle Hotels
- Apartments in Creighton
- Creighton Hotels
- Winside Hotels
- Vacation Homes in Winside
- Hotels near Cuthills Vineyards
- Hotels near Niobrara State Park
- Motels in Randolph
- Hotels near Wayne State College
- Farmstay in Crofton
- Crofton Hotels
- Hotels near Cedar County Historical Museum
- Osmond Hotels
- Pilger Hotels
- Hotels near Wayne County Museum
- Ponca Hotels
- Motels in Ponca
- Vacation Homes in Ponca
- Pender Hotels
- Hadar Hotels
- Pierce Hotels