Book Hotels in Sister Islands

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Sister Islands hotels

Luxury Oceanfront Villa, 2 Primary Suites + 3rd bdrm, Pool

Luxury Oceanfront Villa, 2 Primary Suites + 3rd bdrm, Pool

Stake Bay
This vacation home features an outdoor pool and a hot tub. A garden, laundry facilities, and barbecue grills are also on offer.
July 2025 Visit
"The house was very clean and exactly what we needed. The snorkeling right outside the house was amazing. We would highly recommend this property. The owners were very easy to communicate with and the property manager was wonderful. LOVE IT!!!!"

Reviewed on Aug 2, 2025

Opens in a new windowLuxury Oceanfront Villa, 2 Primary Suites + 3rd bdrm, Pool
Conch Club Cottage

Conch Club Cottage

3 out of 5
1200 Guy Banks Road, Little Cayman, Cayman Islands
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this hotel. Enjoy beachfront dining and relax with free beach cabanas and sun loungers. ...
"The cottage was very nice, with access to bikes, kayaks and 2 pools."

Reviewed on Jul 27, 2025

Opens in a new windowConch Club Cottage
Luxury Beachfront House on Cayman Brac's Nicest Beach! Vacation your way!

Luxury Beachfront House on Cayman Brac's Nicest Beach! Vacation your way!

Cayman Brac
This vacation home features limo/town car service, laundry facilities, and concierge services. Barbecue grills are provided for your convenience.
Hammocks on the beach
"Property was great."

Reviewed on Feb 23, 2025

Opens in a new windowLuxury Beachfront House on Cayman Brac's Nicest Beach! Vacation your way!
Little Cayman Escape - Stunning  Views and Privacy - Call Cayman Villas!

Little Cayman Escape - Stunning Views and Privacy - Call Cayman Villas!

Little Cayman
This villa featured laundry facilities and barbecue grills.
"What a treat to visit this quiet little island and stay in a secluded home with a private beach. With the living space located on second floor, this home has fantastic views of the ocean and reef. We were able to watch boats, wildlife, sunsets, and storms all from this location. The underneath of ..."

Reviewed on Jun 9, 2025

Opens in a new windowLittle Cayman Escape - Stunning Views and Privacy - Call Cayman Villas!
Serenity On The Bay2 - Two Bed Apt Close to Supermarkets, Shops and Restaurants!

Serenity On The Bay2 - Two Bed Apt Close to Supermarkets, Shops and Restaurants!

Cayman Brac
A hot tub is featured at this guesthouse, along with laundry facilities and barbecue grills.
Nice week on the shore
"Nice quiet place on the sea. Mostly rough surf while we were there, but plenty of other easy entry places into water for snorkeling."

Reviewed on Dec 25, 2024

Opens in a new windowSerenity On The Bay2 - Two Bed Apt Close to Supermarkets, Shops and Restaurants!
The Alexander # 210 - Queen Suite

The Alexander # 210 - Queen Suite

West End
$245 nightly
The price is $268 total per night from Sep 29 to Sep 30
$268 total
Sep 29 - Sep 30
Total with taxes and fees
An outdoor pool is featured at this aparthotel, along with laundry facilities.
"Excellent Service Always"

Reviewed on Mar 17, 2025

Opens in a new windowThe Alexander # 210 - Queen Suite
Le Soleil d'Or CaymanBrac

Le Soleil d'Or CaymanBrac

3.5 out of 5
2147 South Side Road, West End
Fully refundableReserve now, pay when you stay
$446 nightly
The price is $492 total per night from Oct 8 to Oct 9
$492 total
Oct 8 - Oct 9
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, ...
"Everything about staying Le Soleil d'Or on Cayman Brac was excellent. The room was spacious and very well maintained. We ate several meals in the resturant and were delighted every time. The property is a great place to be and the cultivation being done there quite fascinating. Regarding the staff, ..."

Reviewed on Aug 22, 2025

Opens in a new windowLe Soleil d'Or CaymanBrac
Beachfront Villa with amazing views- Private pool/Wifi.

Beachfront Villa with amazing views- Private pool/Wifi.

Head o Bay
An outdoor pool is featured at this vacation home, along with laundry facilities and barbecue grills.
Opens in a new windowBeachfront Villa with amazing views- Private pool/Wifi.
Featherstone - The Estate

Featherstone - The Estate

Tibbett's Turn
This vacation home features a garden, laundry facilities, and barbecue grills.
Opens in a new windowFeatherstone - The Estate
Don't see what you're looking for?
See all available properties in Sister Islands
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Sister Islands hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity

Explore More Ways to Travel with Travelocity