Book Hotels in Sister Islands

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Sister Islands hotels

Luxury Beachfront House on Cayman Brac's Nicest Beach! Vacation your way!

Luxury Beachfront House on Cayman Brac's Nicest Beach! Vacation your way!

Cayman Brac Sister Islands
This vacation home features limo/town car service, laundry facilities, and concierge services. Barbecue grills are provided for your convenience.
Hammocks on the beach
Property was great.

Reviewed on Feb 23, 2025

Opens in a new windowLuxury Beachfront House on Cayman Brac's Nicest Beach! Vacation your way!
Little Cayman Escape - Stunning  Views and Privacy - Call Cayman Villas!

Little Cayman Escape - Stunning Views and Privacy - Call Cayman Villas!

Little Cayman Little Cayman
This villa featured laundry facilities and barbecue grills.
What a treat to visit this quiet little island and stay in a secluded home with a private beach. With the living space located on second floor, this home has fantastic views of the ocean and reef. We were able to watch boats, wildlife, sunsets, and storms all from this location. The underneath of ...

Reviewed on Jun 9, 2025

Opens in a new windowLittle Cayman Escape - Stunning Views and Privacy - Call Cayman Villas!
Blossom Village Cottage – Charming Beachfront Cottage by Cayman Villas.

Blossom Village Cottage – Charming Beachfront Cottage by Cayman Villas.

Little Cayman Little Cayman
This villa featured laundry facilities and barbecue grills.
Piece of Paradise
The place is fantastic. Right on the beach. We pretty much had the beach in front of our place to ourselves to swim and relax. The store was out of charcoal bricks for the BBQ but Marc managed to find us a propane BBQ which was great. If you want a place to relax off the beaten path that has fantastic ...

Reviewed on May 18, 2025

Opens in a new windowBlossom Village Cottage – Charming Beachfront Cottage by Cayman Villas.
Serenity On The Bay2 - Two Bed Apt Close to Supermarkets, Shops and Restaurants!

Serenity On The Bay2 - Two Bed Apt Close to Supermarkets, Shops and Restaurants!

Cayman Brac Cayman Islands
A hot tub is featured at this guesthouse, along with laundry facilities and barbecue grills.
This is a place that you will absolutely adore if you like silence except for the waves. This place is not for you if you are picky about every speck of sand. We absolutely adored this cottage. The kitchen is well equipped so we made our own meals and ate on the porch looking at a heron that stalked ...

Reviewed on Nov 29, 2025

Opens in a new windowSerenity On The Bay2 - Two Bed Apt Close to Supermarkets, Shops and Restaurants!
The Alexander # 210 - Queen Suite

The Alexander # 210 - Queen Suite

West End Cayman Brac
$253 nightly
The price is $276 total per night from Dec 8 to Dec 9
$276 total
Dec 8 - Dec 9
Total with taxes and fees
An outdoor pool is featured at this aparthotel, along with laundry facilities.
Pool was not overcrowed

Reviewed on Dec 4, 2025

Opens in a new windowThe Alexander # 210 - Queen Suite
Le Soleil d'Or CaymanBrac

Le Soleil d'Or CaymanBrac

3.5 out of 5
2147 South Side Road West End
Fully refundableReserve now, pay when you stay
$395 nightly
The price is $435 total per night from Dec 17 to Dec 18
$435 total
Dec 17 - Dec 18
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, ...
Everything about staying Le Soleil d'Or on Cayman Brac was excellent. The room was spacious and very well maintained. We ate several meals in the resturant and were delighted every time. The property is a great place to be and the cultivation being done there quite fascinating. Regarding the staff, ...

Reviewed on Aug 22, 2025

Opens in a new windowLe Soleil d'Or CaymanBrac
Ocean view from every room ,quiet neighborhood family friendly.Bluff view

Ocean view from every room ,quiet neighborhood family friendly.Bluff view

Cayman Brac Sister Islands
This vacation home features laundry facilities.
Stay was 1 week and the pool could not be used due to bees and was not cleaned regularly. One bath was out of service because of leak. The place is very nice tho hopefully all issues are fix would stay again.

Reviewed on Jun 2, 2025

Opens in a new windowOcean view from every room ,quiet neighborhood family friendly.Bluff view
Nature Escape Getaway w/ in-room dining service & amenities/3bdrm 1bth/sleeps 5

Nature Escape Getaway w/ in-room dining service & amenities/3bdrm 1bth/sleeps 5

Cayman Brac Cayman Brac
A hot tub is featured at this vacation home, along with a garden and laundry facilities. Concierge services and barbecue grills are also provided.
Lovely stay
Greeted by house manager who took us through the basics. Villa was super clean and very cute. Gorgeous outside area

Reviewed on Jan 2, 2023

Opens in a new windowNature Escape Getaway w/ in-room dining service & amenities/3bdrm 1bth/sleeps 5
The ROCK HOUSE with Private Beach on Little Cayman

The ROCK HOUSE with Private Beach on Little Cayman

Blossom Village Sister Islands
Stay at this vacation home in Little Cayman. Enjoy a beach locale. Popular attractions National Trust Visitors Centre and Little Cayman Beaches are located ...
good location for our stay
great location store, is bike able distance , shallow water snorkeling in front of house lots of conch, screen porch is outstanding feature . older houses like this one are usually in best locations

Reviewed on Mar 28, 2024

Opens in a new windowThe ROCK HOUSE with Private Beach on Little Cayman
Don't see what you're looking for?
See all available properties in Sister Islands
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Sister Islands hotel reviews by fellow wanderers