Book Hotels in Sedgewickville, MO
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Top Sedgewickville hotels

Secluded 5-Bedroom Lodge with Private Lake – Perfect for Large Groups!
Perryville MO
This lodge featured laundry facilities and barbecue grills.
"A peaceful, secluded cabin with a gorgeous view of the lake. Spacious rooms and beautifully decorated. The hosts were welcoming and responsive to any questions that came up before or during our stay. We are already looking forward to our next trip!"
Reviewed on Jul 14, 2025

Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve MO
$329 nightly
The price is $351 total per night from Jun 17 to Jun 18
$351 total
Jun 17 - Jun 18
Total with taxes and fees
This country house features laundry facilities.
"We had an amazing time! Great property and cozy. We had a few dead flies in the bed but otherwise perfect stay!"
Reviewed on Mar 29, 2026

Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $86 total per night from Jun 28 to Jun 29
$86 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"Has a nice gathering place - over breakfast, happy hour, and throughout the day. Considerate of others as it was shut down at 10. Rooms were quieter than many places I’ve stayed."
Reviewed on Jun 14, 2026

Tru By Hilton Cape Girardeau
2520 Veterans Memorial Dr Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $102 total per night from Jul 1 to Jul 2
$102 total
Jul 1 - Jul 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Guests will appreciate freebies like daily breakfast and free self parking. Staff at the 24-hour front desk can ...
"The staff is amazing! We LOVE this hotel."
Reviewed on Jun 11, 2026

Holiday Inn Express & Suites Perryville by IHG
2020 Jefferson St Perryville MO
Fully refundable
$101 nightly
The price is $116 total per night from Jun 18 to Jun 19
$116 total
Jun 18 - Jun 19
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Hotel was very nice and clean. Breakfast was good, except for the bacon. Too greasy for us. Would go back if we head back one day in the future."
Reviewed on Jun 15, 2026

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $100 total per night from Jun 16 to Jun 17
$100 total
Jun 16 - Jun 17
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"The hotel was nice and the staff were nice and professional. I did think it was unnecessary for us to pay a $10 fee because we were an hour early for check in. If the room was ready and we were renting for one night, what difference does it make that we were a little early. I paid the fee because ..."
Reviewed on Jun 15, 2026

Super 8 by Wyndham Perryville
1119 Vincent Dr Perryville MO
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $81 total per night from Jun 22 to Jun 23
$81 total
Jun 22 - Jun 23
Total with taxes and fees
This motel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Ok on cleanliness but needed more staff cleaning breakfast room"
Reviewed on Jun 10, 2026

Quality Inn Cape Girardeau North
2011 North Kingshighway Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Jun 22 to Jun 23
$76 total
Jun 22 - Jun 23
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi ...
"The sink and tub barely drained and the air conditioner was so loud"
Reviewed on Jun 11, 2026

Days Inn by Wyndham Perryville
1500 Liberty Street Perryville MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $77 total per night from Jun 22 to Jun 23
$77 total
Jun 22 - Jun 23
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"The first room we were given had not been cleaned; dirty towels on the floor, unmade bed. The 2nd room we were given had dirty sheets. The front desk gave us new sheets which when we went to put them on the bed were stained and when removing the dirty sheets, the mattress topper had blood on it. ..."
Reviewed on Jun 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Sedgewickville hotel reviews by fellow wanderers

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
5 out of 5
Posted 8 hours ago
Travelocity Verified Review
"The hotel was nice and the staff were nice and professional. I did think it was unnecessary for us to pay a $10 fee because we were an hour early for check in. If the room was ready and we were renting for one night, what difference does it make that we were a little early. I paid the fee because I didn't think that the hotel would appreciate all of us sitting in the hotel lobby drinking. We were on the road for 4 hours and ready to relax. Also, when asking for extra towels and an extra blanket I felt like I was being accused of stealing....they made sure to check our room number and marked it down that we got extras like we were going to steal them...I'm sure it happens a lot and is a huge expense, but it just didn't sit right with me. There were cobwebs in our bathroom that I did not notice until the next morning and our comforter on our bed was dirty...did not notice that until it was too late either. It is easy to access and close to where we needed to be. The way the shower was situated made out bathroom floor wet, which is an accident waiting to happen. The shower needs some sort of barrier. The free breakfast in the morning was adequate...coffee, eggs, sausage, waffles, fruit, toast, muffins, bagels, juice, cereal, milk. The AC in the room was great. "
A verified traveler stayed at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau






