Book Hotels in Sedgewickville, MO
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Top Sedgewickville hotels

Secluded 5-Bedroom Lodge with Private Lake – Perfect for Large Groups!
Perryville MO
This lodge featured laundry facilities and barbecue grills.
A peaceful, secluded cabin with a gorgeous view of the lake. Spacious rooms and beautifully decorated. The hosts were welcoming and responsive to any questions that came up before or during our stay. We are already looking forward to our next trip!
Reviewed on Jul 14, 2025

Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve MO
$331 nightly
The price is $353 total per night from Apr 7 to Apr 8
$353 total
Apr 7 - Apr 8
Total with taxes and fees
This farm stay features laundry facilities.
We felt welcomed from the minute we stepped inside. My husband and I spent Valentines Day weekend touring the local wineries and rather than going out for dinner with tons of other people, we enjoyed pizza and wine at the Silo.
Reviewed on Feb 16, 2026

Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $85 total per night from Apr 13 to Apr 14
$85 total
Apr 13 - Apr 14
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
I’ve stayed at this hotel twice now while visiting family in the area. The property itself is very nice—clean, well‑maintained, and in a great location right off the interstate. The staff has also been friendly during both of my stays. However, both times my mom and I were placed in the exact same ...
Reviewed on Apr 4, 2026

Holiday Inn Express & Suites Perryville by IHG
2020 Jefferson St Perryville MO
Fully refundable
$101 nightly
The price is $116 total per night from Apr 12 to Apr 13
$116 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
It was fine but the pancake batter was out.
Reviewed on Apr 3, 2026

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $96 total per night from Apr 9 to Apr 10
$96 total
Apr 9 - Apr 10
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Yes the Church of Jesus Christ is just up the road about 3 miles 😊
Reviewed on Apr 6, 2026

Super 8 by Wyndham Perryville
1119 Vincent Dr Perryville MO
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $73 total per night from Apr 12 to Apr 13
$73 total
Apr 12 - Apr 13
Total with taxes and fees
This motel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Good breakfast and clean rooms.
Reviewed on Mar 28, 2026

Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd Jackson MO
Fully refundable
$92 nightly
The price is $100 total per night from Apr 12 to Apr 13
$100 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Rooms were clean, AC worked great and the staff was friendly
Reviewed on Apr 3, 2026

Quality Inn Cape Girardeau North
2011 North Kingshighway Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from Apr 13 to Apr 14
$75 total
Apr 13 - Apr 14
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like English breakfast and WiFi in public ...
It was a clean room at a fair price. No frills but clean and staff were polite.
Reviewed on Mar 31, 2026

Tru By Hilton Cape Girardeau
2520 Veterans Memorial Dr Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $111 total per night from Apr 12 to Apr 13
$111 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Guests will appreciate freebies like daily breakfast and free self parking. Staff at the 24-hour front desk can ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Sedgewickville hotel reviews by fellow wanderers

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
5 out of 5
Posted 5 hours ago
Travelocity Verified Review
"Yes the Church of Jesus Christ is just up the road about 3 miles 😊"
A verified traveler stayed at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau






