Book Hotels in Sedgewickville, MO
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Top Sedgewickville hotels

Secluded 5-Bedroom Lodge with Private Lake – Perfect for Large Groups!
Perryville MO
This lodge featured laundry facilities and barbecue grills.
A peaceful, secluded cabin with a gorgeous view of the lake. Spacious rooms and beautifully decorated. The hosts were welcoming and responsive to any questions that came up before or during our stay. We are already looking forward to our next trip!
Reviewed on Jul 14, 2025

Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve MO
$327 nightly
The price is $349 total per night from Apr 29 to Apr 30
$349 total
Apr 29 - Apr 30
Total with taxes and fees
This farm stay features laundry facilities.
We had an amazing time! Great property and cozy. We had a few dead flies in the bed but otherwise perfect stay!
Reviewed on Mar 29, 2026

Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $85 total per night from May 25 to May 26
$85 total
May 25 - May 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Beds was not soft
Reviewed on Apr 26, 2026

Tru By Hilton Cape Girardeau
2520 Veterans Memorial Dr Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $111 total per night from May 4 to May 5
$111 total
May 4 - May 5
Total with taxes and fees
This hotel features an indoor pool and a gym. Guests will appreciate freebies like daily breakfast and free self parking. Staff at the 24-hour front desk can ...
This is a clean, quiet, well designed hotel.
Reviewed on Apr 24, 2026

Holiday Inn Express & Suites Perryville by IHG
2020 Jefferson St Perryville MO
Fully refundable
$101 nightly
The price is $116 total per night from Apr 30 to May 1
$116 total
Apr 30 - May 1
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
No
Reviewed on Apr 22, 2026

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $96 total per night from Apr 30 to May 1
$96 total
Apr 30 - May 1
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Room was as advertised. Staff friendly. Breakfast was eggs, sausage patty, waffle maker, etc. the juice machine was broken both days we stayed and there was no alternative option. Pool was nice being indoor
Reviewed on Apr 26, 2026

Super 8 by Wyndham Perryville
1119 Vincent Dr Perryville MO
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $76 total per night from May 3 to May 4
$76 total
May 3 - May 4
Total with taxes and fees
This motel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Could be better
Reviewed on Apr 20, 2026

Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd Jackson MO
Fully refundable
$92 nightly
The price is $100 total per night from Apr 30 to May 1
$100 total
Apr 30 - May 1
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
It was way below average and was not a cheap property to stay at. Very dirty room, bathroom was disgusting. Breakfast was mediocre. Pool area was even dirty. Front desk clerk was also doing the breakfast area. Wore the same gloves from food area, to front desk, back to food area.
Reviewed on Apr 18, 2026

Quality Inn Cape Girardeau North
2011 North Kingshighway Cape Girardeau MO
Fully refundable
$67 nightly
The price is $75 total per night from Apr 29 to Apr 30
$75 total
Apr 29 - Apr 30
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like English breakfast and WiFi in public ...
It appears there are several projects in progress (lots of recently filled holes in the walls that remain unpainted) but its also clear that many things still need attention. The staff were welcoming and friendly.
Reviewed on Apr 26, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Sedgewickville hotel reviews by fellow wanderers

EC Reed's Mercantile and Hotel
5 out of 5
Posted 12 hours ago
Travelocity Verified Review
"Great place to stay! Nostalgic dining connected to hotel is pretty cool. If nearby, for sure stay with them."
A verified traveler stayed at EC Reed's Mercantile and Hotel






