Book Hotels in Sedgewickville, MO
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Sedgewickville hotels
Secluded 5-Bedroom Lodge with Private Lake – Perfect for Large Groups!
Perryville MO
This lodge featured laundry facilities and barbecue grills.
A peaceful, secluded cabin with a gorgeous view of the lake. Spacious rooms and beautifully decorated. The hosts were welcoming and responsive to any questions that came up before or during our stay. We are already looking forward to our next trip!
Reviewed on Jul 14, 2025
Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve MO
$329 nightly
The price is $351 total per night from Mar 24 to Mar 25
$351 total
Mar 24 - Mar 25
Total with taxes and fees
This farm stay features laundry facilities.
We felt welcomed from the minute we stepped inside. My husband and I spent Valentines Day weekend touring the local wineries and rather than going out for dinner with tons of other people, we enjoyed pizza and wine at the Silo.
Reviewed on Feb 16, 2026
Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $85 total per night from Apr 5 to Apr 6
$85 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
We have never stayed at a Drury hotel before and we were pleasantly surprised by amenities that are different from the usual hotel chains. Such as complimentary supper along with breakfast. Definitely a great deal when traveling with a family! Since we travel through the area often, we’ll definitely ...
Reviewed on Mar 21, 2026
Holiday Inn Express & Suites Perryville by IHG
2020 Jefferson St Perryville MO
Fully refundable
$95 nightly
The price is $109 total per night from Mar 29 to Mar 30
$109 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
I was told i could check in when im 18 but i got their and they would not let me after already paying the price for it. Rip off. Very disrespectful.
Reviewed on Mar 21, 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $96 total per night from Mar 29 to Mar 30
$96 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Hotel staff were friendly and helpful. Store and restaurants were a short drive away.
Reviewed on Mar 17, 2026
Super 8 by Wyndham Perryville
1119 Vincent Dr Perryville MO
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $75 total per night from Apr 5 to Apr 6
$75 total
Apr 5 - Apr 6
Total with taxes and fees
This motel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Clean room
Reviewed on Mar 22, 2026
Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd Jackson MO
Fully refundable
$92 nightly
The price is $100 total per night from Mar 29 to Mar 30
$100 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
There was no water pressure, luke warm water both nights. The breakfast was subpar & with an hour left with breakfast the workers refused to refill empty items. Several people complained to no avail. Breakfast area was dirty & two people sitting upfront playing on their phones. We made our first ...
Reviewed on Mar 22, 2026
Town House Inn
517 E Jackson Blvd Jackson MO
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $72 total per night from Mar 31 to Apr 1
$72 total
Mar 31 - Apr 1
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. The front desk is staffed around-the-clock and laundry facilities are ...
Great owners
Reviewed on Mar 3, 2026
Quality Inn Cape Girardeau North
2011 North Kingshighway Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from Mar 29 to Mar 30
$75 total
Mar 29 - Mar 30
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like English breakfast and WiFi in public ...
It was ok no elevator though
Reviewed on Mar 22, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Sedgewickville hotel reviews by fellow wanderers
Comfort Suites Jackson-Cape Girardeau
2 out of 5
Posted 4 hours ago
Travelocity Verified Review
"There was no water pressure, luke warm water both nights. The breakfast was subpar & with an hour left with breakfast the workers refused to refill empty items. Several people complained to no avail. Breakfast area was dirty & two people sitting upfront playing on their phones. We made our first & last stay here!!"
A verified traveler stayed at Comfort Suites Jackson-Cape Girardeau
