Book Hotels in Sedgewickville, MO
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Top Sedgewickville hotels

Secluded 5-Bedroom Lodge with Private Lake – Perfect for Large Groups!
Perryville MO
This lodge featured laundry facilities and barbecue grills.
"This property is amazing and the hosts are fantastic!! We stay at a lot of rentals and this was by far the cleanest, best stocked home we have ever rented. There was such thought put into providing guests with every single thing they may need - and there was no skimping!! Plus, we received an over ..."
Reviewed on Aug 25, 2026

Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve MO
$331 nightly
The price is $370 total per night from Nov 5 to Nov 6
$370 total
Nov 5 - Nov 6
Total with taxes and fees
This vacation home features laundry facilities.
"Visited for the weekend with my wife to celebrate our anniversary. The Silo Farm Haus was absolutely perfect! The views of the rolling farmland were gorgeous. Inside was cozy and beautifully decorated. We had a wonderful time and would highly recommend staying here if you get the chance."
Reviewed on Oct 19, 2026

Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $85 total per night from Nov 15 to Nov 16
$85 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"The hotel was clean, comfortable and the breakfast was good."
Reviewed on Nov 3, 2026

Quality Inn Cape Girardeau North
2011 North Kingshighway Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $67 total per night from Nov 15 to Nov 16
$67 total
Nov 15 - Nov 16
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi ...
"Es un hotel sucio no lo recomiendo"
Reviewed on Oct 31, 2026

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $86 total per night from Nov 8 to Nov 9
$86 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...

Days Inn by Wyndham Perryville
1500 Liberty Street Perryville MO
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $82 total per night from Nov 5 to Nov 6
$82 total
Nov 5 - Nov 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...

Tru By Hilton Cape Girardeau
2520 Veterans Memorial Dr Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $97 total per night from Nov 11 to Nov 12
$97 total
Nov 11 - Nov 12
Total with taxes and fees
This hotel features an indoor pool and a gym. Guests will appreciate freebies like daily breakfast and free self parking. Staff at the 24-hour front desk can ...

Holiday Inn Express & Suites Perryville by IHG
2020 Jefferson St Perryville MO
Fully refundable
$101 nightly
The price is $116 total per night from Nov 8 to Nov 9
$116 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...

Super 8 by Wyndham Perryville
1119 Vincent Dr Perryville MO
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $79 total per night from Nov 15 to Nov 16
$79 total
Nov 15 - Nov 16
Total with taxes and fees
This motel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Sedgewickville hotel reviews by fellow wanderers

Drury Inn & Suites Jackson MO
5 out of 5
Posted 22 hours ago
Travelocity Verified Review
"The hotel was clean, comfortable and the breakfast was good."
A verified traveler stayed at Drury Inn & Suites Jackson MO




