Book Hotels in Sedgewickville, MO
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Sedgewickville hotels
Secluded 5-Bedroom Lodge with Private Lake – Perfect for Large Groups!
Perryville MO
This lodge featured laundry facilities and barbecue grills.
"A peaceful, secluded cabin with a gorgeous view of the lake. Spacious rooms and beautifully decorated. The hosts were welcoming and responsive to any questions that came up before or during our stay. We are already looking forward to our next trip!"
Reviewed on Jul 14, 2025
Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve MO
$331 nightly
The price is $353 total per night from Jun 10 to Jun 11
$353 total
Jun 10 - Jun 11
Total with taxes and fees
This country house features laundry facilities.
"We had an amazing time! Great property and cozy. We had a few dead flies in the bed but otherwise perfect stay!"
Reviewed on Mar 29, 2026
Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $85 total per night from Jun 21 to Jun 22
$85 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"Well kept and very clean. Very friendly staff. Worth the price !! Would stay again!"
Reviewed on Jun 8, 2026
Tru By Hilton Cape Girardeau
2520 Veterans Memorial Dr Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $102 total per night from Jul 1 to Jul 2
$102 total
Jul 1 - Jul 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Guests will appreciate freebies like daily breakfast and free self parking. Staff at the 24-hour front desk can ...
"I would like to say that the staff are some of the nicest people I’ve encountered while traveling. Expedia messed up with the payment and it was a 2 hour process to undo it. But the hotel staff were amazing and did everything in their power to resolve the issue."
Reviewed on May 28, 2026
Holiday Inn Express & Suites Perryville by IHG
2020 Jefferson St Perryville MO
Fully refundable
$101 nightly
The price is $116 total per night from Jun 15 to Jun 16
$116 total
Jun 15 - Jun 16
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Beautiful new hotel didn’t disappoint! Rey comfortable beds. Great breakfast and attentive staff keeping things filed for the best guest experience. I would definitely stop there again on my next trip through Perryville!"
Reviewed on Jun 7, 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $100 total per night from Jun 10 to Jun 11
$100 total
Jun 10 - Jun 11
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Air didn’t work in our room and they didn’t have another room for us and would not give us a refund"
Reviewed on Jun 7, 2026
Super 8 by Wyndham Perryville
1119 Vincent Dr Perryville MO
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $81 total per night from Jun 15 to Jun 16
$81 total
Jun 15 - Jun 16
Total with taxes and fees
This motel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"The room was ok but the bed was very hard & uncomfortable."
Reviewed on May 26, 2026
Quality Inn Cape Girardeau North
2011 North Kingshighway Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Jun 15 to Jun 16
$76 total
Jun 15 - Jun 16
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi ...
"First and foremost I booked the room because there was supposed to be an outdoor pool, no water in it when I arrived. Staff had no idea if the bedding and pillows were hypoallergenic. Your breakfast options were bread, bagels or waffles, no meat options. Place was overall pretty dirty. Even at $100, ..."
Reviewed on Jun 8, 2026
Days Inn by Wyndham Perryville
1500 Liberty Street Perryville MO
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $82 total per night from Jun 10 to Jun 11
$82 total
Jun 10 - Jun 11
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"The first room we were given had not been cleaned; dirty towels on the floor, unmade bed. The 2nd room we were given had dirty sheets. The front desk gave us new sheets which when we went to put them on the bed were stained and when removing the dirty sheets, the mattress topper had blood on it. ..."
Reviewed on Jun 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Sedgewickville hotel reviews by fellow wanderers
Drury Inn & Suites Jackson MO
5 out of 5
Posted 9 hours ago
Travelocity Verified Review
"Well kept and very clean. Very friendly staff. Worth the price !! Would stay again!"
A verified traveler stayed at Drury Inn & Suites Jackson MO
