Book Hotels in Sedgewickville, MO
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Top Sedgewickville hotels

Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve
$329 nightly
The price is $350 total per night from Jul 23 to Jul 24
$350 total
Jul 23 - Jul 24
Total includes taxes and fees
This farm stay features a water park and laundry facilities.
"We had such a wonderful anniversary weekend at the silo. It was beautiful and well maintained, both inside and out. Very well stocked kitchen, and plenty of towels. It was so peaceful sitting on the porch swing with a cup of coffee and driving to the nearby wineries was great. We even stopped by ..."
Reviewed on Jun 17, 2025

Drury Inn & Suites Jackson MO
225 Drury Lane, Jackson, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $95 total per night from Jul 27 to Jul 28
$95 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"Excellent stay"
Reviewed on Jul 14, 2025

Tru By Hilton Cape Girardeau
2520 Veterans Memorial Dr, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $115 total per night from Jul 28 to Jul 29
$115 total
Jul 28 - Jul 29
Total includes taxes and fees
This hotel features an indoor pool and a gym. Guests will appreciate freebies like daily breakfast and free self parking. Staff at the 24-hour front desk can ...
"We have stayed in a lot of hotels and this by far was the best one we stayed in. We had left Gatlinburg and the hotel was crap there. We just happen to take a. Different way home and came across this one and man what a relief it was. The room was very clean and the bed, in my opinion the most important ..."
Reviewed on Jul 20, 2025

Holiday Inn Express & Suites Perryville by IHG
2020 Jefferson St, Perryville, MO
Fully refundable
$105 nightly
The price is $120 total per night from Aug 14 to Aug 15
$120 total
Aug 14 - Aug 15
Total includes taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Staff was helpful"
Reviewed on Jul 15, 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $101 total per night from Jul 24 to Jul 25
$101 total
Jul 24 - Jul 25
Total includes taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Hotel was clean. Large dining area. Was able to accommodate our large group"
Reviewed on Jul 14, 2025

Super 8 by Wyndham Perryville
1119 Vincent Dr, Perryville, MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $78 total per night from Jul 30 to Jul 31
$78 total
Jul 30 - Jul 31
Total includes taxes and fees
This motel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Cleanliness was good. Staff was helpful."
Reviewed on Jul 14, 2025

Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd, Jackson, MO
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $92 total per night from Jul 23 to Jul 24
$92 total
Jul 23 - Jul 24
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Great area, fast check in, quiet, very spacious"
Reviewed on Jun 29, 2025

Quality Inn
2011 North Kingshighway, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $76 total per night from Jul 23 to Jul 24
$76 total
Jul 23 - Jul 24
Total includes taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like English breakfast and WiFi in public ...
"This was the second stay in a weeks time. Different room but the bed still squeaked, same as the room across the hall. My husband thinks it is the bedframe when you sit on the bed or stand from it. Otherwise quite comfortable"
Reviewed on Jul 17, 2025

Secluded 5-Bedroom Lodge with Private Lake – Perfect for Large Groups!
Perryville
This lodge featured laundry facilities and barbecue grills.
"A peaceful, secluded cabin with a gorgeous view of the lake. Spacious rooms and beautifully decorated. The hosts were welcoming and responsive to any questions that came up before or during our stay. We are already looking forward to our next trip!"
Reviewed on Jul 14, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Sedgewickville hotel reviews by fellow wanderers

Tru By Hilton Cape Girardeau
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"We have stayed in a lot of hotels and this by far was the best one we stayed in. We had left Gatlinburg and the hotel was crap there. We just happen to take a. Different way home and came across this one and man what a relief it was. The room was very clean and the bed, in my opinion the most important part of the room, was amazing. Got up for breakfast and absolutely loved it. We will be looking for more hotels with this name on our travels. "
A verified traveler stayed at Tru By Hilton Cape Girardeau
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An Attraction
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