Book Hotels in Sedgewickville, MO
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Top Sedgewickville hotels
Secluded 5-Bedroom Lodge with Private Lake – Perfect for Large Groups!
Perryville MO
This lodge featured laundry facilities and barbecue grills.
A peaceful, secluded cabin with a gorgeous view of the lake. Spacious rooms and beautifully decorated. The hosts were welcoming and responsive to any questions that came up before or during our stay. We are already looking forward to our next trip!
Reviewed on Jul 14, 2025
Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve MO
$331 nightly
The price is $353 total per night from May 5 to May 6
$353 total
May 5 - May 6
Total with taxes and fees
This farm stay features laundry facilities.
We had an amazing time! Great property and cozy. We had a few dead flies in the bed but otherwise perfect stay!
Reviewed on Mar 29, 2026
Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $85 total per night from May 14 to May 15
$85 total
May 14 - May 15
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Very friendly staff and very clean
Reviewed on May 3, 2026
Tru By Hilton Cape Girardeau
2520 Veterans Memorial Dr Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $111 total per night from May 10 to May 11
$111 total
May 10 - May 11
Total with taxes and fees
This hotel features an indoor pool and a gym. Guests will appreciate freebies like daily breakfast and free self parking. Staff at the 24-hour front desk can ...
This is a clean, quiet, well designed hotel.
Reviewed on Apr 24, 2026
Holiday Inn Express & Suites Perryville by IHG
2020 Jefferson St Perryville MO
Fully refundable
$101 nightly
The price is $116 total per night from May 10 to May 11
$116 total
May 10 - May 11
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
The rooms were spacious with black.out curtains. Beds and pillows were comfy. The only thing I can complain about was the breakfast. I expected a little more, but it wasn't awful. I thought it would include biscuits and gravy. Very minor issue. I would definitely stay there again.
Reviewed on May 3, 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $106 total per night from May 5 to May 6
$106 total
May 5 - May 6
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Great place to stay. The breakfast could be better.
Reviewed on Apr 27, 2026
Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd Jackson MO
Fully refundable
$92 nightly
The price is $100 total per night from May 13 to May 14
$100 total
May 13 - May 14
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Air Conditioning was noisy, the bathroom door did not close. The linens were dingy. The furniture was subpar, lots of damage on them scratches and dings. The carpet was stained and dirty, the bathroom had water damage around the tub and there were cracks in the ceiling drywall.
Reviewed on Apr 27, 2026
Quality Inn Cape Girardeau North
2011 North Kingshighway Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from May 10 to May 11
$75 total
May 10 - May 11
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like English breakfast and WiFi in public ...
Parking was great! Breakfast needs alot of improvement. But all together was a great experience!
Reviewed on Apr 27, 2026
Super 8 by Wyndham Perryville
1119 Vincent Dr Perryville MO
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $81 total per night from May 10 to May 11
$81 total
May 10 - May 11
Total with taxes and fees
This motel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Sedgewickville hotel reviews by fellow wanderers
Drury Inn & Suites Jackson MO
5 out of 5
Posted 21 hours ago
Travelocity Verified Review
"Very friendly staff and very clean"
A verified traveler stayed at Drury Inn & Suites Jackson MO
