Deals on vacations and trips to Santiago

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Santiago flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,262, price is now $775 per person
$775
per person
Sep 28 - Oct 4
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
This smoke-free resort features a casino, 2 indoor tennis courts, and a restaurant. Bring the family and enjoy the children's pool, playground, and kid-friendly dining. Enjoy the outdoor pool and free perks like full breakfast and valet parking.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,720, price is now $851 per person
$851
per person
Sep 12 - Sep 17
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Save 100% on your flight
Price was $1,486, price is now $857 per person
$857
per person
Sep 28 - Oct 4
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,732, price is now $1,142 per person
$1,142
per person
Sep 12 - Sep 17
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Free WiFi in public areas is available at this apartment. Take advantage of the self parking.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,208, price is now $803 per person
$803
per person
Sep 28 - Oct 4
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.

Top Santiago hotels deals

Hotel Gran David

Hotel Gran David

3.5 out of 5
Vía Interamericana Santiago Veraguas
Free Cancellation
Reserve now, pay when you stay
$57 nightly
The price is $63 total per night
$63 total
Jul 22 - Jul 23
Total with taxes and fees
This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Relax with a drink at the bar/lounge and enjoy free perks like cooked-to-order breakfast and free self parking. There's a poolside bar on site, and laundry facilities and concierge services are also provided.
Pool
Breakfast included
HOTEL CORPORATIVO PLAZA COROTÚ

HOTEL CORPORATIVO PLAZA COROTÚ

3 out of 5
Carr. Panamericana Santiago Provincia de Veraguas
Get rates
A restaurant, free self parking, and a 24-hour front desk are among this hotel's amenities. WiFi in public areas is free. Express check-out is also provided.
Pet friendly
Parking included
Minutes from downtown Santiago, Chicho Fábrega hospital and Universidad Latina.

Minutes from downtown Santiago, Chicho Fábrega hospital and Universidad Latina.

Panama Panamá
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This vacation home includes a garden and laundry facilities.
Kitchen
Washer
HOTEL PLAZA COROTÚ

HOTEL PLAZA COROTÚ

2 out of 5
Carr. Panamericana Santiago Provincia de Veraguas
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Free WiFi in public areas is provided and the front desk is staffed around-the-clock. Laundry facilities are provided for your convenience.
Pet friendly
Free WiFi
Hostal Travelers

Hostal Travelers

2 out of 5
Santiago de Veraguas Santiago Veraguas
Get rates
This hostal doesn't skimp on freebies - guests receive free WiFi and free self parking. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including food and water bowls. A terrace, a garden, and a snack bar/deli are also on offer.
Pet friendly
Parking included
Hotel Mykonos Panama

Hotel Mykonos Panama

3.5 out of 5
Panamerican Highway Nuevo Santiago Veraguas
Free Cancellation
Reserve now, pay when you stay
$83 nightly
The price is $91 total per night
$91 total
Jul 22 - Jul 23
Total with taxes and fees
This smoke-free hotel features a full-service spa, 3 outdoor pools, and a restaurant. There's fun for all ages with a children's pool and a playground, and families will appreciate the onsite laundry facilities. Enjoy the gym and free perks like cooked-to-order breakfast and valet parking.
Pool
Breakfast included
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See all available properties in Santiago
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santiago attractions

Escuela Normal Juan Demostenes Arosemena

9.2/10 (9 reviews)
Explore the campus of Escuela Normal Juan Demostenes Arosemena, during your trip to Santiago. Stroll along the lakeside or visit the cathedral while you're in the area.
See properties

Frequently asked questions

How much are vacation packages to Santiago?
Packages, which provide both flights and hotels in Santiago, start from $775. Turn your travel fantasies into reality and book your trip with Travelocity today.
Where can I get the best vacation package deals for Santiago?
You'll come across a terrific selection of Santiago package deals on Travelocity. With as many as 400 airlines and 1,000,000 properties worldwide, crafting the ultimate escape will be a piece of cake.
Why should I purchase my Santiago vacation package with Travelocity?
Travel is all about making cherished new memories and leaving all your troubles behind — which is why we provide you with a team of experts on hand around-the-clock should you need them. On top of that, our Price Match Guarantee ensures you'll always get the best price available on our terrific range of destinations. So what are you waiting for? There's no time like the present to lock in that vacation you've always wanted.
Can I save on my Santiago car rental if I book it with a hotel or flight?
With a Santiago vacation package, you can combine your hotel, car and flight bookings and save loads. If you want to see the best of this fabulous area, why not start with Miraflores Locks? This popular sight is 110 mi from Santiago. With a rental car, you'll be there before you know it.
What is there to do in Santiago?
While getting off the beaten track can be rewarding, you really shouldn't miss the big-name sights that make a place famous. Catedral of Santiago Apostol and Omar Torrijos Herrera Stadium are a couple of them in Santiago.
Where should I stay when visiting Santiago?
The Hotel Gran David is popular with many travelers. Book now before it's too late.

Photos of local treasures

Browse Santiago vacation photos for more inspiration

A coastal archaeological site with ruins and boats on the water.
A mountainous landscape with rolling hills and scattered buildings.
A historic fort with lush green grass and palm trees in the background.
A coastal fort with a cannon, a small tower, and a clear blue sea with boats in the background.
A stone pier with a small tower, boats in the water, and a green hillside in the background.