
Deals on vacations and trips to Santiago
Save when you book Santiago package deals

Santiago flight + hotel vacation packages
Price found within the past 48 hours. Click for updated prices.

Hotel Riu Plaza Panama
Bella Vista
Price was $998, price is now $678 per person
$678
per person
Feb 15 - Feb 20
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.

Megapolis Hotel Panamá
San Francisco
Save 100% on your flight
Price was $1,442, price is now $925 per person
$925
per person
Feb 15 - Feb 20
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.

Playa Caracol Residences Vacation Rental
Save 100% on your flight
Price was $1,283, price is now $853 per person
$853
per person
Feb 7 - Feb 14
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
This smoke-free apartment features 2 outdoor pools, a restaurant, and a bar/lounge. Relax with a drink at the poolside bar and enjoy perks like free self parking. A coffee shop and a snack bar/deli are also provided.

Villa Botero By Casa Mojito B&B
Price was $1,248, price is now $875 per person
$875
per person
Mar 4 - Mar 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
This bed & breakfast features an outdoor pool and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. An area shuttle, a casino shuttle, and laundry facilities are also offered.

Riande Aeropuerto Hotel & Casino
Price was $1,034, price is now $762 per person
$762
per person
Feb 15 - Feb 20
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
This smoke-free resort features a casino, 2 indoor tennis courts, and a restaurant. Bring the family and enjoy the children's pool, playground, and kid-friendly dining. Enjoy the outdoor pool and free perks like full breakfast and valet parking.
Top Santiago hotels deals

Hotel Gran David
Vía Interamericana Santiago Veraguas
Free Cancellation
Reserve now, pay when you stay
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and onsite conference space. Enjoy the 24-hour gym and free perks like cooked-to-order breakfast and free self parking.
Pool
Breakfast included

The Spring Loft | Santiago
Santiago Provincia de Veraguas
A garden is available at this apartment.
Pet friendly
Free WiFi

HOTEL PLAZA COROTÚ
Carr. Panamericana Santiago Provincia de Veraguas
Free WiFi in public areas is provided and the front desk is staffed around-the-clock. Laundry facilities are provided for your convenience.
Pet friendly
Free WiFi

Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone
Santiago Provincia de Veraguas
Stay at this vacation home in Santiago. Enjoy air conditioning. Popular attractions Plaza Banconal and Omar Torrijos Herrera Stadium are located nearby.
Pet friendly
Air conditioning

Hostal Travelers
Santiago de Veraguas Santiago Veraguas
This hostal doesn't skimp on freebies - guests receive free WiFi and free self parking. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including food and water bowls. A terrace, a garden, and a snack bar/deli are also on offer.
Pet friendly
Parking included

Hotel Mykonos Panama
Panamerican Highway Nuevo Santiago Veraguas
Free Cancellation
Reserve now, pay when you stay
$85 nightly
The price is $94 total per night
$94 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
This smoke-free hotel features a full-service spa, 3 outdoor pools, and a restaurant. There's fun for all ages with a children's pool and a playground, and families will appreciate the onsite laundry facilities. Enjoy the gym and free perks like cooked-to-order breakfast and valet parking.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Escuela Normal Juan Demostenes Arosemena
Explore the campus of Escuela Normal Juan Demostenes Arosemena, during your trip to Santiago. Stroll along the lakeside or visit the cathedral while you're in the area.
Catedral of Santiago Apostol
Find out about the history of Santiago when you take a trip to Catedral of Santiago Apostol. Amble around the area's lakeside or visit its cathedral.
Omar Torrijos Herrera Stadium
Catch an event at Omar Torrijos Herrera Stadium during your trip to Santiago. Amble around the area's lakeside or visit its cathedral.
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