Santiago Vacation Packages 2026 from $594

Santiago flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

San Blas Tour Aridub

$594

per person

Jul 21 - Jul 24

found 6 hours ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

An outdoor pool is available at this cabin.

Central Hotel Panama Casco Viejo

Casco Viejo

Save 100% on your flight

$896

per person

Aug 27 - Aug 31

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.

Megapolis Hotel Panamá

San Francisco

$835

per person

Aug 27 - Aug 31

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.

Discovery Gunayar

$624

per person

Jul 21 - Jul 24

found 6 hours ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

san blas luxury tour

$690

per person

Jul 21 - Jul 24

found 6 hours ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

This cabin doesn't skimp on freebies - guests receive free full breakfast and a free beach shuttle. Relax with beach cabanas and beach umbrellas, and cool off with a drink at the beachside bar. You'll appreciate the area shuttle, beach bar, and a virtual front desk.

Top Santiago hotels deals

Hotel Gran David

Vía Interamericana Santiago Veraguas

Free Cancellation

Reserve now, pay when you stay

$74 nightly

$82 total

Jul 1 - Jul 2

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and onsite conference space. Enjoy the 24-hour gym and free perks like cooked-to-order breakfast and free self parking.

Pool

Breakfast included

HOTEL CORPORATIVO PLAZA COROTÚ

Carr. Panamericana Santiago Provincia de Veraguas

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A restaurant, free self parking, and a 24-hour front desk are among this hotel's amenities. WiFi in public areas is free. Express check-out is also provided.

Pet friendly

Parking included

HOTEL PLAZA COROTÚ

Carr. Panamericana Santiago Provincia de Veraguas

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Free WiFi in public areas is provided and the front desk is staffed around-the-clock. Laundry facilities are provided for your convenience.

Pet friendly

Free WiFi

Minutes from downtown Santiago, Chicho Fábrega hospital and Universidad Latina.

Panama Panamá

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This vacation home includes a garden and laundry facilities.

Kitchen

Washer

Hostal Travelers

Santiago de Veraguas Santiago Veraguas

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This hostal doesn't skimp on freebies - guests receive free WiFi and free self parking. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including food and water bowls. A terrace, a garden, and a snack bar/deli are also on offer.

Pet friendly

Parking included

Hotel Mykonos Panama

Panamerican Highway Nuevo Santiago Veraguas

Free Cancellation

Reserve now, pay when you stay

$91 nightly

$101 total

Jun 21 - Jun 22

Total with taxes and fees

This smoke-free hotel features a full-service spa, 3 outdoor pools, and a restaurant. There's fun for all ages with a children's pool and a playground, and families will appreciate the onsite laundry facilities. Enjoy the gym and free perks like cooked-to-order breakfast and valet parking.

Pool

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much are vacation packages to Santiago?

Packages, which provide both flights and hotels in Santiago, start from $594. Turn your travel fantasies into reality and book your trip with Travelocity today.

Where can I get the best vacation package deals for Santiago?

You'll come across a terrific selection of Santiago package deals on Travelocity. With as many as 400 airlines and 1,000,000 properties worldwide, crafting the ultimate escape will be a piece of cake.

Why should I purchase my Santiago vacation package with Travelocity?

Travel is all about making cherished new memories and leaving all your troubles behind — which is why we provide you with a team of experts on hand around-the-clock should you need them. On top of that, our Price Match Guarantee ensures you'll always get the best price available on our terrific range of destinations. So what are you waiting for? There's no time like the present to lock in that vacation you've always wanted.

Can I save on my Santiago car rental if I book it with a hotel or flight?

With a Santiago vacation package, you can combine your hotel, car and flight bookings and save loads. If you want to see the best of this fabulous area, why not start with Miraflores Locks? This popular sight is 110 mi from Santiago. With a rental car, you'll be there before you know it.

What is there to do in Santiago?

While getting off the beaten track can be rewarding, you really shouldn't miss the big-name sights that make a place famous. Catedral of Santiago Apostol and Omar Torrijos Herrera Stadium are a couple of them in Santiago.

Where should I stay when visiting Santiago?

The Hotel Gran David is popular with many travelers. Book now before it's too late.