Book Hotels in Santiago Sur
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Top Santiago Sur hotels
Catalina's Hideaway
Lagartero Beach Hicaco Veraguas
This lodge features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and airport shuttle. ...
"La atención muy especial, el hotel divino y tranquilo, las camas cómodas y la comida excepcional 🙌"
Reviewed on Jun 6, 2026
Hotel Santa Catalina Panama
Calle hacia el Estero Hicaco Veraguas
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $114 total per night from Sep 17 to Sep 18
$114 total
Sep 17 - Sep 18
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Relax with a drink at the poolside bar and enjoy perks like free self parking and free WiFi. ...
"The view amazing ... the kitchen wasn't available half of platea we order es"
Reviewed on Sep 14, 2026
Hotel Plaza Los Tucanes
Vía interamericana Nuevo Santiago Provincia de Veraguas
Fully refundableReserve now, pay when you stay
$52 nightly
The price is $57 total per night from Sep 17 to Sep 18
$57 total
Sep 17 - Sep 18
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free cooked-to-order breakfast, free WiFi, and free self parking. Business travelers can take advantage ...
"No hot water in the shower, bathroom door wouldn't open all the way because the basin was in the way, room is minuscule, no iron, no safety deposit box, no hair dryer."
Reviewed on Aug 29, 2026
Hotel Mykonos Panama
Panamerican Highway Nuevo Santiago Veraguas
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $87 total per night from Oct 4 to Oct 5
$87 total
Oct 4 - Oct 5
Total with taxes and fees
This smoke-free hotel features a full-service spa, 3 outdoor pools, and a restaurant. There's fun for all ages with a children's pool and a playground, and families ...
"Me encantó mi estadía en Hotel Mykonos. La habitación fue muy cómoda, mis hijos disfrutaron muchísimo la piscina y el servicio fue excelente. ❤️ Lo que más me encantó fue la comida del restaurante. La amapola (piña colada virgen) estaba espectacular, ¡10/10! 🍍🥥 De las mejores que he probado en ..."
Reviewed on Sep 15, 2026
Hotel Gran David
Vía Interamericana Santiago Veraguas
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $71 total per night from Sep 18 to Sep 19
$71 total
Sep 18 - Sep 19
Total with taxes and fees
This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Relax with a drink at the bar/lounge and enjoy free perks like cooked-to-order breakfast ...
"Z"
Reviewed on Sep 13, 2026
Hotel y Restaurante Mama Ines
Calle Hacia Playa Estero Hicaco Veraguas Province
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $72 total per night from Oct 11 to Oct 12
$72 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Relax with a drink at the poolside bar and enjoy free perks like cooked-to-order breakfast ...
"loved the location and pool looking out at the beach, everything was great, except that the top bunk bed didn't have anything to stop someone from falling out so we couldn't use it"
Reviewed on Sep 14, 2026
Cabañas Palma Real
Las Colomas, Santiago Sur via principal Santiago Sur Provincia de Veraguas
$68 nightly
The price is $75 total per night from Sep 17 to Sep 18
$75 total
Sep 17 - Sep 18
Total with taxes and fees
An outdoor pool, free self parking, and barbecue grills are featured at this cabin. WiFi in public areas is free. A terrace and a garden are also provided.
Bambuda Santa Catalina
Finca 464377 Hicaco Veraguas
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $83 total per night from Oct 4 to Oct 5
$83 total
Oct 4 - Oct 5
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
Villa Coco
Via Catalina Farms Hicaco Veraguas
$130 nightly
The price is $143 total per night from Sep 20 to Sep 21
$143 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. There's fun for all ages with a children's pool and a playground, and barbecue grills are ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Santiago Sur hotel reviews by fellow wanderers
Hotel Mykonos Panama
5 out of 5
Posted 7 hours ago
Travelocity Verified Review
"Me encantó mi estadía en Hotel Mykonos. La habitación fue muy cómoda, mis hijos disfrutaron muchísimo la piscina y el servicio fue excelente. ❤️ Lo que más me encantó fue la comida del restaurante. La amapola (piña colada virgen) estaba espectacular, ¡10/10! 🍍🥥 De las mejores que he probado en Panamá. Además, la ubicación al lado de Santiago Mall es súper conveniente. Quedé muy satisfecha y definitivamente pienso regresar. ¡Mis hijos también quedaron encantados! 🙌❤️"
A verified traveler stayed at Hotel Mykonos Panama
