Book Hotels in Santee, NE

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Sep 11 - Sep 13
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Sep 18 - Sep 20

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Top Santee hotels

Fully furnished lake house with cozy spaces, full kitchen, and lake views.

Fully furnished lake house with cozy spaces, full kitchen, and lake views.

Crofton NE
This vacation home features laundry facilities.
"Very accommodating."

Reviewed on Aug 10, 2026

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Opens in a new windowFully furnished lake house with cozy spaces, full kitchen, and lake views.
Gavins Point Lakehouse

Gavins Point Lakehouse

Yankton SD
This vacation home includes a garden and laundry facilities.
"Beautiful spacious home with high end furnishings that was exceptionally well stocked through out. It accomodated our 4 generation group of 10 adults and 6 young children. We all had privacy and could settle down after a busy day. And we all easily gathered in the main living areas as well. We would ..."

Reviewed on Jul 22, 2026

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Opens in a new windowGavins Point Lakehouse
Newly Remodeled Creekside Bungalow on 3 acres with private Beach/Creek access

Newly Remodeled Creekside Bungalow on 3 acres with private Beach/Creek access

Verdigre NE
$219 nightly
The price is $242 total per night from Sep 13 to Sep 14
$242 total
Sep 13 - Sep 14
Total with taxes and fees
This vacation home features barbecue grills.
"Very inviting setting. The fire ring and chairs on the beach were fantastic. The house was clean and well stocked with essentials. The beds were comfortable. This property is conveniently located between Verdigre and Niobrara. There were 4 of us over the age of 60 and we all were very satisfied. ..."

Reviewed on Sep 2, 2026

Opens in a new window Newly Remodeled Creekside Bungalow on 3 acres with private Beach/Creek access
Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!

Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!

Crofton NE
$989 nightly
The price is $1,093 total per night from Sep 8 to Sep 9
$1,093 total
Sep 8 - Sep 9
Total with taxes and fees
This vacation home features a garden, laundry facilities, and barbecue grills.
"Very clean and good space for big groups!"

Reviewed on Jul 19, 2026

Opens in a new windowModern Lewis and Clark lake home with lake views and 3 min drive to the beach!
Cozy cabin near Lewis and Clark Lake and CJ’s at the Lake

Cozy cabin near Lewis and Clark Lake and CJ’s at the Lake

Crofton NE
Stay at this cabin in Crofton. Enjoy air conditioning. Popular attractions Deep Water Recreation Area and Lewis and Clark Lake State Recreation Area are located ...
"Checked all the boxes for what we needed for this stay, thanks Tony !"

Reviewed on Aug 2, 2026

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Opens in a new windowCozy cabin near Lewis and Clark Lake and CJ’s at the Lake
Charming Lake House within Walking Distance from Lake

Charming Lake House within Walking Distance from Lake

Yankton SD
This vacation home features a garden, laundry facilities, and barbecue grills.
"Great location and great host! Quick communication from Katie every time. Very family-friendly!"

Reviewed on Jul 31, 2026

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Opens in a new windowCharming Lake House within Walking Distance from Lake
Haven by the Lake

Haven by the Lake

Yankton SD
This vacation home features a garden, laundry facilities, and barbecue grills.
"Amazing place to stay at, great access to the water, lots of space, overall great experience!"

Reviewed on Aug 31, 2026

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Opens in a new windowHaven by the Lake
Spacious Lakeview Cabin Minutes from Private Beach

Spacious Lakeview Cabin Minutes from Private Beach

Crofton NE
This cabin featured laundry facilities and barbecue grills.
"Lots of room for sleeping - open spacious living room with a beautiful lake view."

Reviewed on Aug 23, 2026

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Opens in a new windowSpacious Lakeview Cabin Minutes from Private Beach
Lewis and Clark Resort

Lewis and Clark Resort

2.5 out of 5
43496 Shore Drive Yankton SD
$90 nightly
The price is $95 total per night from Sep 8 to Sep 9
$95 total
Sep 8 - Sep 9
Total with taxes and fees
A marina and a restaurant are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
"Great views..very adequate accommodations..huge outlying natural area to relax in..do it again!"

Reviewed on Sep 3, 2026

Opens in a new windowLewis and Clark Resort
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Santee?
From cool amenities to extra space, kid-friendly hotels come with features that can help transform a routine family vacation into a sensational one. These Santee options make vacationing with your youngsters child's play: The whole team will enjoy their time at Private updated hunting lodge/farmhouse. Pet-friendly facilities and a barbecue grill are just a few of the things that help make this property a favorite. Bear Historic Home is another excellent choice. After an exciting day of exploring, come home to your cozy room and amenities like a king bed and animal viewing activities.
Where can I find cheap hotels in Santee?
At Travelocity you'll find really nice hotels in Santee at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santee rather than in Santee. We may find you even better rates, too.
How do I find the best Santee hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santee then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santee?
The cheapest hotel in Santee is $95. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santee?
There are 68 hotels in Santee on Travelocity.
What are the best hotels in Santee?
Santee has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santee for you!
When is the best time to visit Santee?
If you want the joy of a fun-filled trip in peak season, visit Santee during May, July and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Santee?
Based on historic data is usually the cheapest month to visit Santee. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santee?
There are multiple hotels in Santee that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santee. We have plenty of kid-friendly hotels in Santee to choose from on Travelocity!
Why book a hotel in Santee through Travelocity?
Because we have the top hotels in Santee! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santee on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santee hotel reviews by fellow wanderers

Lewis and Clark Resort

Lewis and Clark Resort

5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Great views..very adequate accommodations..huge outlying natural area to relax in..do it again!"
A verified traveler stayed at Lewis and Clark Resort
Lewis and Clark Resort

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