Book Hotels in Santee, NE
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Top Santee hotels

Cozy Cabin get away - walking distant to beach
Crofton
This cabin featured laundry facilities and barbecue grills.
"Hosts were great and very helpful. House was clean and had everything we needed. 10/10"
Reviewed on Aug 17, 2025

Haven by the Lake
Yankton
This vacation home features a garden, laundry facilities, and barbecue grills.
"Had a great time with family and conveniently located close to Lewis and Clark Lake. There was so much to do around the house as well. We had a foosball tournament one night. It was great, hopefully we can do it again sometime. Lindsay was responsive, check in and check out was a breeze."
Reviewed on Sep 4, 2025

Gavins Point Lakehouse
Yankton
This vacation home includes a garden and laundry facilities.
Simply Stunning
"Property was stunning. Views from the home are stunning and the memories we made were u forgettable. Beds and pillows were all comfortable and the kitchen was stocked with the tools to allow you to prepare whatever upur heart desired. Communication was simple and responses were quick. Definitely ..."
Reviewed on Aug 3, 2025

Shady Creek Cabin - Family Friendly Getaway Near Lake
Yankton
This cabin features a water park, a garden, and laundry facilities. Barbecue grills are provided for your convenience.
"We had a wonderful time. The place was excellent. We enjoyed the gas fire pit and the house was clean and in great condition. I would recommend this to anyone!"
Reviewed on Sep 29, 2025

Lake property just a few blocks from public beach. Marina a mile away.
Crofton
This vacation home featured laundry facilities and barbecue grills.
"Very clean, location was great.will be booking again."
Reviewed on Jul 30, 2025

ThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18
Yankton
$833 nightly
The price is $875 total per night from Oct 21 to Oct 22
$875 total
Oct 21 - Oct 22
Total with taxes and fees
A water park and a hot tub are featured at this smoke-free vacation home. Families will appreciate the playground and barbecue grills. Limo/town car service, ...
"Great house. The deck was a great spot for hanging out and entertaining. Good amenities. Good communication from host. Would rent again if we were back in the area"
Reviewed on Sep 9, 2025

Charming Lake House within Walking Distance from Lake
Yankton
$463 nightly
The price is $486 total per night from Nov 8 to Nov 9
$486 total
Nov 8 - Nov 9
Total with taxes and fees
This vacation home features a garden, laundry facilities, and barbecue grills.
"Nice property, nice location."
Reviewed on Sep 15, 2025

Spacious Lakeview Cabin Minutes from Private Beach
Crofton
This cabin featured laundry facilities and barbecue grills.
"Property worked out well for us"
Reviewed on Oct 6, 2025

Lewis and Clark Resort
43496 Shore Drive, Yankton, SD
$98 nightly
The price is $104 total per night from Oct 30 to Oct 31
$104 total
Oct 30 - Oct 31
Total with taxes and fees
A marina and a restaurant are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
"nice place"
Reviewed on Oct 11, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Santee hotel reviews by fellow wanderers

Lewis and Clark Resort
5 out of 5
Posted 8 days ago
Travelocity Verified Review
"Everything was great"
A verified traveler stayed at Lewis and Clark Resort