
Deals on vacations and trips to Santa Isabel
Save when you book Santa Isabel package deals
Santa Isabel flight + hotel vacation packages
Price found within the past 48 hours. Click for updated prices.

Nomada Republic Hotel Punta Chame
per person
Aug 30 - Sep 4
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
A private beach and an outdoor pool are featured at this hotel. Relax with sun loungers and beach umbrellas, and cool off with a drink at the beachside bar. Enjoy a meal from the restaurant and perks like free self parking and free WiFi.

Central Hotel Panama Casco Viejo
Casco Viejo
per person
Sep 30 - Oct 7
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.

Villa Botero By Casa Mojito B&B
per person
Sep 28 - Oct 3
found 9 hours ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
This bed & breakfast features an outdoor pool and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. An area shuttle, a casino shuttle, and laundry facilities are also offered.

The Gray by Wynwood House
Bella Vista
Save 100% on your flight
per person
Oct 2 - Oct 7
found 4 hours ago
Roundtrip non-stop flight included
New York (JFK) to Panama City (PTY)
An indoor pool is featured at this apartment, along with free self parking. Staff at the 24-hour front desk can provide around-the-clock assistance.

Casa Fofo Family House
per person
Sep 28 - Oct 3
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
An outdoor pool, free self parking, and laundry facilities are featured at this guesthouse. WiFi in public areas is free. A terrace, a garden, and barbecue grills are also on offer.
Top Santa Isabel hotels deals

Private Ocean-Front Cabin with private bathroom on San Blas Island
Diablo Island, Narganá, Guna Yala
This hotel features a restaurant, a garden, and a snack bar/deli. Enjoy the free local cuisine breakfast each morning.
Breakfast included
Restaurant

Private Over the Water Cabin on San Blas Island
9.542876, -78.899058, Narganá, San Blas
This cabin features a restaurant, a coffee shop, and a terrace. Enjoy the free local cuisine breakfast each morning. A garden and a snack bar/deli are also provided.
Breakfast included
Kitchen

San Blas Paradise Private Cabins on Shipwreck Island - meals included
Perro Island, Narganá, Guna Yala
Book a stay at this beach hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Diablo and Isla Chichime are located nearby.
Breakfast included

Cabins in Asserya Island - San Blas paradise - meals included
Aroma Island (Isla Anzuelo), Narganá, Guna Yala
A marina and a restaurant are featured at this hotel. Enjoy the free local cuisine breakfast each morning. You'll appreciate the area shuttle and snack bar/deli.
Breakfast included
Restaurant

Paradise Over the Water Cabins in San Blas
G4V2 48, Narganá, Guna Yala
A restaurant is available at this cabin. Enjoy the free continental breakfast each morning.
Breakfast included
Restaurant
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Photos of local treasures
Browse Santa Isabel vacation photos for more inspiration