COVID-19 alert: Travel requirements are changing rapidly, including need for pre-travel COVID-19 testing and quarantine on arrival.

Exclusive deals on vacations and trips to Santa Isabel

Choose one or more items to build your trip:

Santa Isabel flight + hotel packages

AC Hotel by Marriott Panama City
The Westin Panama
Marriott Executive Apartments Panama City, Finisterre
Summit Rainforest & Golf Resort

Top Santa Isabel hotels deals

Don't see what you're looking for?
See all available properties in Santa Isabel
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

^Savings based on all package bookings with Flight + Hotel made on from 2019-04-01 - 2020-03-31 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.