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Top Santa Fe hotels

Hotel Anachoreo
Nice room, comfortable. A/C. The grounds were beautifully landscaped and had many options for spending time outdoors sitting, talking, working, napping, watching wild birds, or eating at the al fresco restaurant. The staff worked hard to make our stay enjoyable. Volcancito’s weather was drier and ...
Reviewed on Feb 25, 2026

HOTEL VISTA LAGO
el lugar está hermoso! rica comida,
Reviewed on Feb 18, 2026

Hotel La Hacienda
Hotel with lots of colors. Reception area is fantastic. Chairs, wall are painted with hundreds of colors. Calm hotel with polite staff.
Reviewed on Aug 2, 2016

Private Over the Water Cabin on San Blas Island
Very nice. And I liked the food
Reviewed on Aug 14, 2025

La Qhia Eco Retreat

Cabana Vergara Santa Fe

Rainforest Yasmin Hotel

House on wheels, with mountain views and direct access to the Santa Maria River.

Hostal Brisas Calobre ñas
Santa Fe Hotel & Travel Guide\n
There are limited hotel options on Travelocity in or around Santa Fe's center. Make sure you book as soon as you're ready if you'd like to stay close to Santa Fe's action.
The Coffee Mountain Inn is one of the best-situated Travelocity-listed accommodation options, one of a small number of places within an easy stroll of the Santa Fe center.
1 mile (2 kilometers) outside the middle of Santa Fe is the Coffee Mountain Inn.
Still looking for things to do? You could spend some time exploring Catedral San Juan Bautista and Herrera Museum, which you'll find in Chitre, 60 miles (93 kilometers) to the southeast of Santa Fe. If you're planning to get to Chitre, check out the rooms at the Los Guayacanes and Gran Hotel Azuero. For another option, stay in Santa Catalina, 60 miles (96 kilometers) south of Santa Fe, where you can pick from the Cabañas Time Out and Hotel Santa Catalina Panama. The Lagartero Beach and El Banco Beach are some of the more popular places to explore in Santa Catalina.
If you think of yourself as a fan of all things sports, make sure you watch an exciting game at Omar Torrijos Herrera Stadium before your time in Panama is up Why not stay close to the stadium at the Hotel Mykonos Panama.
For those travelers traveling through Marcos A. Gelabert International Airport, you might want to stay at The Canal House, or American Trade Hotel, each of which are close.
Frequently asked questions
Recent Santa Fe hotel reviews by fellow wanderers





