Explore 15 Luxury Hotels in Sanibel

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Best Luxury Hotels in Sanibel

Island Inn

Island Inn

3111 W Gulf Dr, Sanibel, FL
$259 nightly
The price is $289 total per night from Oct 5 to Oct 6
$289 total
Oct 5 - Oct 6
Total with taxes and fees
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Spend a day at the beach surfing, or relax with sun loungers and ...
9.4/10 Exceptional! (1,105 reviews)
"Amazing views from Matthews Lodge!!!! This is my third stay (first time after hurricane Ian) and every time the staff, from the office staff to the maintenance team to the housekeeping team are ALL amazing! Always right there to tend to every need with a smile! I don’t think there is ever a day they ..."

Reviewed on Sep 27, 2025

Opens in a new windowIsland Inn
Kona Kai Motel

Kona Kai Motel

1539 Periwinkle Way, Sanibel, FL
$164 nightly
The price is $183 total per night from Oct 3 to Oct 4
$183 total
Oct 3 - Oct 4
Total with taxes and fees
An outdoor pool, free self parking, and barbecue grills are featured at this motel. WiFi in public areas is free. A garden is also provided.
8.8/10 Excellent! (929 reviews)
"This a a beautiful location. Quite a unique experience for a hotel, and absolutely somewhere I'll be back. Not pet friendly, but thats okay. The whole setup is just the perfect island vacation location. I literally cannot say enough good stuff about this hotel."

Reviewed on Sep 28, 2025

Opens in a new windowKona Kai Motel
Sanibel Inn

Sanibel Inn

937 East Gulf Drive, Sanibel, FL
Fully refundableReserve now, pay when you stay
$346 nightly
The price is $386 total per night from Nov 1 to Nov 2
$386 total
Nov 1 - Nov 2
Total with taxes and fees
A private beach and an outdoor pool are featured at this smoke-free hotel. Spend a day at the beach kayaking, or relax with sun loungers and beach umbrellas. ...
8.8/10 Excellent! (1,004 reviews)
"The grounds are beautifully landscaped. The staff were friendly and very accommodating. Our suite had a gulf view and was newly renovated. We enjoyed the quiet peaceful atmosphere and I was even blessed to see a glorious sunrise from my balcony!"

Reviewed on Sep 26, 2025

Opens in a new windowSanibel Inn
Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

1451 Middle Gulf Drive, Sanibel, FL
$432 nightly
The price is $482 total per night from Oct 16 to Oct 17
$482 total
Oct 16 - Oct 17
Total with taxes and fees
A full-service spa, 4 restaurants, and 2 outdoor pools are all featured at this luxury condo resort. Enjoy beachfront dining and relax with sun loungers and ...
8.6/10 Excellent! (2,576 reviews)
"The ocean view 1 minute to the beach"

Reviewed on Sep 22, 2025

Opens in a new windowSundial Beach Resort & Spa
Seaside Inn

Seaside Inn

541 E Gulf Dr, Sanibel, FL
A private beach and an outdoor pool are featured at this smoke-free vacation home. Enjoy the outdoor tennis court and free perks like continental breakfast and ...
Not safe for toddlers
"Main issue was that the door does not have a toddler proof lock. Like there is no chain or bar at top. So basically my toddler could open the door and run outside to the pool at will. So that was very stressful. They were hard to get ahold of at front desk but besides those things amenities were ..."

Reviewed on Sep 26, 2022

Opens in a new windowSeaside Inn
Sunset Beach Inn

Sunset Beach Inn

3287 West Gulf Drive, Sanibel, FL
A private beach and an outdoor pool are featured at this smoke-free hotel. Enjoy a day at the beach kayaking, or relax with sun loungers. Enjoy the outdoor tennis ...
Enjoyable
"We enjoyed our stay very much . We loved being so close to the beautiful beach. The room was a bit outdated but very clean and comfortable."

Reviewed on Sep 24, 2022

Opens in a new windowSunset Beach Inn
Anchor Inn and Cottages

Anchor Inn and Cottages

1245 Periwinkle Way, Sanibel Island, Sanibel, FL
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. If you want to take your pet along, this pet-friendly property offers ...
"Very nice stay - the host was exceptionally friendly and it is a peaceful place - great location and the room was exactly what we were looking for. Nice mini-lake with lots of nature behind the property. Would highly recommend this place!"

Reviewed on Jan 6, 2023

Opens in a new windowAnchor Inn and Cottages
West Wind Inn

West Wind Inn

3345 West Gulf Drive, Sanibel, FL
This vacation home features 2 bars/lounges, a beach bar, and a restaurant. Enjoy the outdoor pool and perks like free WiFi. A poolside bar, a 24-hour front desk, ...
"Nice"

Reviewed on Sep 22, 2022

Opens in a new windowWest Wind Inn
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More 4 star hotels in Sanibel

5 star hotels in Sanibel

Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

1451 Middle Gulf Drive, Sanibel, FL
$432 nightly
The price is $482 total per night from Oct 16 to Oct 17
$482 total
Oct 16 - Oct 17
Total with taxes and fees
8.6/10 Excellent! (2,576 reviews)

Sanibel Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Sanibel luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Sanibel to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Sanibel will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Sanibel, and plan your next opulent escape.


Sanibel hotels essential information

Accommodation
1,778 hotels
Lowest Price
$183
Highest Price
$482
Popular hotels
Sundial Beach Resort & Spa, Seaside Inn, Sunset Beach Inn, Anchor Inn and Cottages, West Wind Inn, Kona Kai Motel, Sanibel Inn, Island Inn

Popular Luxury Stays in Sanibel

Recent Sanibel Hotel Reviews By Fellow Wanderers

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