Explore 15 Luxury Hotels in Sanibel

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Best Luxury Hotels in Sanibel

Island Inn

3111 W Gulf Dr, Sanibel, FL

$219 nightly

$244 total

Sep 29 - Sep 30

Total with taxes and fees

This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Spend a day at the beach surfing, or relax with sun loungers and ...

9.4/10 Exceptional! (1,103 reviews)

"A great place to enjoy the beach. Beautiful sunsets, We will definitely be back to Island Inn. Thanks for a great vacation!!!"

Reviewed on Sep 20, 2025

Kona Kai Motel

1539 Periwinkle Way, Sanibel, FL

Fully refundableReserve now, pay when you stay

$164 nightly

$183 total

Sep 27 - Sep 28

Total with taxes and fees

An outdoor pool, free self parking, and barbecue grills are featured at this motel. WiFi in public areas is free. A garden is also provided.

8.8/10 Excellent! (928 reviews)

"What a wonderful surprise. Kona Kai did not disappoint in any category. Our room was beautiful. The beds and pillows were so comfortable. The pool was pristine. It’s a short drive to the beach and some wonderful places to dine. We will definitely stay here again."

Reviewed on Sep 22, 2025

Sanibel Inn

937 East Gulf Drive, Sanibel, FL

Fully refundableReserve now, pay when you stay

$319 nightly

$356 total

Sep 28 - Sep 29

Total with taxes and fees

A private beach and an outdoor pool are featured at this smoke-free hotel. Spend a day at the beach kayaking, or relax with sun loungers and beach umbrellas. ...

8.8/10 Excellent! (1,001 reviews)

"Very beautiful and just a very short walk to the beach"

Reviewed on Sep 12, 2025

Sundial Beach Resort & Spa

1451 Middle Gulf Drive, Sanibel, FL

$457 nightly

$510 total

Oct 9 - Oct 10

Total with taxes and fees

A full-service spa, 4 restaurants, and 4 outdoor tennis courts are all featured at this luxury condo resort. Enjoy beachfront dining and relax with sun loungers ...

8.6/10 Excellent! (2,576 reviews)

"The ocean view 1 minute to the beach"

Reviewed on Sep 22, 2025

Seaside Inn

541 E Gulf Dr, Sanibel, FL

A private beach and an outdoor pool are featured at this smoke-free vacation home. Enjoy the outdoor tennis court and free perks like continental breakfast and ...

Not safe for toddlers

"Main issue was that the door does not have a toddler proof lock. Like there is no chain or bar at top. So basically my toddler could open the door and run outside to the pool at will. So that was very stressful. They were hard to get ahold of at front desk but besides those things amenities were ..."

Reviewed on Sep 26, 2022

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Sunset Beach Inn

3287 West Gulf Drive, Sanibel, FL

A private beach and an outdoor pool are featured at this smoke-free hotel. Enjoy a day at the beach kayaking, or relax with sun loungers. Enjoy the outdoor tennis ...

Enjoyable

"We enjoyed our stay very much . We loved being so close to the beautiful beach. The room was a bit outdated but very clean and comfortable."

Reviewed on Sep 24, 2022

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Anchor Inn and Cottages

1245 Periwinkle Way, Sanibel Island, Sanibel, FL

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. If you want to take your pet along, this pet-friendly property offers ...

"Very nice stay - the host was exceptionally friendly and it is a peaceful place - great location and the room was exactly what we were looking for. Nice mini-lake with lots of nature behind the property. Would highly recommend this place!"

Reviewed on Jan 6, 2023

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West Wind Inn

3345 West Gulf Drive, Sanibel, FL

This vacation home features 2 bars/lounges, a beach bar, and a restaurant. Enjoy the outdoor pool and perks like free WiFi. A poolside bar, a 24-hour front desk, ...

"Nice"

Reviewed on Sep 22, 2022

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Sanibel

Serene Ocean View Escape at Sundial Resort

Sanibel

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5 star hotels in Sanibel

Sundial Beach Resort & Spa

1451 Middle Gulf Drive, Sanibel, FL

$457 nightly

$510 total

Oct 9 - Oct 10

Total with taxes and fees

8.6/10 Excellent! (2,576 reviews)

Sanibel Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Sanibel luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Sanibel to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Sanibel will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Sanibel, and plan your next opulent escape.

Sanibel hotels essential information

Accommodation	1,773 hotels
Lowest Price	$183
Highest Price	$510
Popular hotels	Sundial Beach Resort & Spa, Seaside Inn, Sunset Beach Inn, Anchor Inn and Cottages, West Wind Inn, Kona Kai Motel, Sanibel Inn, Island Inn