Explore 15 Luxury Hotels in Sanibel

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Best Luxury Hotels in Sanibel

Island Inn

3111 W Gulf Dr Sanibel FL

$259 nightly

$289 total

Jul 19 - Jul 20

Total with taxes and fees

This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Spend a day at the beach surfing, or relax with sun loungers and ...

9.4/10 Exceptional! (1,139 reviews)

"Beautiful location"

Reviewed on Jun 24, 2026

Sanibel Inn

937 East Gulf Drive Sanibel FL

Fully refundableReserve now, pay when you stay

$450 nightly

$502 total

Aug 2 - Aug 3

Total with taxes and fees

A private beach and an outdoor pool are featured at this smoke-free hotel. Spend a day at the beach kayaking, or relax with sun loungers and beach umbrellas. ...

9.2/10 Wonderful! (1,006 reviews)

"I had a wonderful stay at this hotel. The room was clean, comfortable, and well maintained. The staff was friendly, welcoming, and always willing to help with any questions. The location was convenient, and the amenities made the stay even more enjoyable. I would definitely stay here again and highly ..."

Reviewed on Jul 6, 2026

Kona Kai Motel

1539 Periwinkle Way Sanibel FL

$184 nightly

$206 total

Jul 13 - Jul 14

Total with taxes and fees

An outdoor pool, free self parking, and barbecue grills are featured at this motel. WiFi in public areas is free. A garden is also provided.

9/10 Wonderful! (1,003 reviews)

"Awesome stay in Sanibel! This was such a cute, practical, and clean place. The set up is so cute and you really feel like you’re on a tropical vacation. I will definitely be staying here again! Loved everything about it, especially the pool and tables outside with the ring toss game."

Reviewed on Jul 9, 2026

Seaside Inn

541 E Gulf Dr Sanibel FL

A private beach and an outdoor pool are featured at this smoke-free vacation home. Enjoy the outdoor tennis court and free perks like continental breakfast and ...

8.8/10 Excellent! (1,000 reviews)

Not safe for toddlers

"Main issue was that the door does not have a toddler proof lock. Like there is no chain or bar at top. So basically my toddler could open the door and run outside to the pool at will. So that was very stressful. They were hard to get ahold of at front desk but besides those things amenities were ..."

Reviewed on Sep 26, 2022

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West Wind Inn

3345 West Gulf Drive Sanibel FL

This vacation home features 2 bars/lounges, a beach bar, and a restaurant. Enjoy the outdoor pool and perks like free WiFi. A poolside bar, a 24-hour front desk, ...

8.8/10 Excellent! (1,000 reviews)

"Nice"

Reviewed on Sep 22, 2022

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Sundial Beach Resort & Spa

1451 Middle Gulf Drive Sanibel FL

$458 nightly

$511 total

Aug 2 - Aug 3

Total with taxes and fees

A full-service spa, 4 restaurants, and 2 outdoor pools are all featured at this luxury aparthotel. Enjoy beachfront dining and relax with sun loungers and beach ...

8.6/10 Excellent! (2,664 reviews)

"Excelente lugar,sin duda volvería a vicitarlo"

Reviewed on Jul 7, 2026

Anchor Inn and Cottages

1245 Periwinkle Way Sanibel FL

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. If you want to take your pet along, this pet-friendly property offers ...

8.6/10 Excellent! (606 reviews)

"Very nice stay - the host was exceptionally friendly and it is a peaceful place - great location and the room was exactly what we were looking for. Nice mini-lake with lots of nature behind the property. Would highly recommend this place!"

Reviewed on Jan 6, 2023

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Sunset Beach Inn

3287 West Gulf Drive Sanibel FL

A private beach and an outdoor pool are featured at this smoke-free hotel. Enjoy a day at the beach kayaking, or relax with sun loungers. Enjoy the outdoor tennis ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Sanibel

A Peace of Heaven

1442 Sandpiper Circle Sanibel FL

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5 star hotels in Sanibel

Sundial Beach Resort & Spa

1451 Middle Gulf Drive Sanibel FL

$458 nightly

$511 total

Aug 2 - Aug 3

Total with taxes and fees

8.6/10 Excellent! (2,664 reviews)

Sanibel Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Sanibel luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Sanibel to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Sanibel will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Sanibel, and plan your next opulent escape.

Sanibel hotels essential information

Accommodation	2,147 hotels
Lowest Price	$206
Highest Price	$511
Popular hotels	Sundial Beach Resort & Spa, Seaside Inn, Sunset Beach Inn, Anchor Inn and Cottages, West Wind Inn, Kona Kai Motel, Sanibel Inn, Island Inn