Explore 15 Luxury Hotels in Sanibel

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Best Luxury Hotels in Sanibel

Island Inn

Island Inn

3111 W Gulf Dr Sanibel FL
$279 nightly
The price is $311 total per night from Jun 25 to Jun 26
$311 total
Jun 25 - Jun 26
Total with taxes and fees
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Spend a day at the beach surfing, or relax with sun loungers and ...
9.4/10 Exceptional! (1,138 reviews)
"Absolutely wonderful! Every detail of this aparthotel lived up to its billing. Walked out of the screened patio onto the private beach. Stunningly decorated room. Perfect 10!"

Reviewed on Jun 6, 2026

Opens in a new windowIsland Inn
Sanibel Inn

Sanibel Inn

937 East Gulf Drive Sanibel FL
Fully refundableReserve now, pay when you stay
$480 nightly
The price is $535 total per night from Jun 14 to Jun 15
$535 total
Jun 14 - Jun 15
Total with taxes and fees
A private beach and an outdoor pool are featured at this smoke-free hotel. Spend a day at the beach kayaking, or relax with sun loungers and beach umbrellas. ...
9.2/10 Wonderful! (1,011 reviews)
"We thought the hotel was perfect. We frequent sanibel. Staying in almost a different place everytime. This place is definelty not the cheapest. But everything was on point. Clean beautiful. My kids really appreciated the kayak and paddle boards. So did their grandmother actually. We will be back ..."

Reviewed on Jun 8, 2026

Opens in a new windowSanibel Inn
Kona Kai Motel

Kona Kai Motel

1539 Periwinkle Way Sanibel FL
$205 nightly
The price is $229 total per night from Jun 15 to Jun 16
$229 total
Jun 15 - Jun 16
Total with taxes and fees
An outdoor pool, free self parking, and barbecue grills are featured at this motel. WiFi in public areas is free. A garden is also provided.
9/10 Wonderful! (1,006 reviews)
"We were pleasantly surprised at how nice the place was. The staff were friendly and the grounds were well taken care of. The pool was a nice addition. The room was spacious and very clean. The air conditioner was nice but took a little while to figure out the remote control. We have already said ..."

Reviewed on Jun 11, 2026

Opens in a new windowKona Kai Motel
Seaside Inn

Seaside Inn

541 E Gulf Dr Sanibel FL
A private beach and an outdoor pool are featured at this smoke-free vacation home. Enjoy the outdoor tennis court and free perks like continental breakfast and ...
8.8/10 Excellent! (1,000 reviews)
Not safe for toddlers
"Main issue was that the door does not have a toddler proof lock. Like there is no chain or bar at top. So basically my toddler could open the door and run outside to the pool at will. So that was very stressful. They were hard to get ahold of at front desk but besides those things amenities were ..."

Reviewed on Sep 26, 2022

Opens in a new windowSeaside Inn
West Wind Inn

West Wind Inn

3345 West Gulf Drive Sanibel FL
This vacation home features 2 bars/lounges, a beach bar, and a restaurant. Enjoy the outdoor pool and perks like free WiFi. A poolside bar, a 24-hour front desk, ...
8.8/10 Excellent! (1,000 reviews)
"Nice"

Reviewed on Sep 22, 2022

Opens in a new windowWest Wind Inn
Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

1451 Middle Gulf Drive Sanibel FL
$498 nightly
The price is $555 total per night from Jun 14 to Jun 15
$555 total
Jun 14 - Jun 15
Total with taxes and fees
A full-service spa, 4 restaurants, and 2 outdoor pools are all featured at this luxury aparthotel. Enjoy beachfront dining and relax with sun loungers and beach ...
8.6/10 Excellent! (2,654 reviews)
"I stayed at this property with my husband for almost a week. Super quick walk to the beach from our room and the hotel provides chairs and umbrellas. Our favorite amenity was the bikes that they let you check out. We rode the bikes all over the Island and it was wonderful. The staff refreshed our ..."

Reviewed on Jun 1, 2026

Opens in a new windowSundial Beach Resort & Spa
Anchor Inn and Cottages

Anchor Inn and Cottages

1245 Periwinkle Way Sanibel FL
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. If you want to take your pet along, this pet-friendly property offers ...
8.6/10 Excellent! (606 reviews)
"Very nice stay - the host was exceptionally friendly and it is a peaceful place - great location and the room was exactly what we were looking for. Nice mini-lake with lots of nature behind the property. Would highly recommend this place!"

Reviewed on Jan 6, 2023

Opens in a new windowAnchor Inn and Cottages
Sunset Beach Inn

Sunset Beach Inn

3287 West Gulf Drive Sanibel FL
A private beach and an outdoor pool are featured at this smoke-free hotel. Enjoy a day at the beach kayaking, or relax with sun loungers. Enjoy the outdoor tennis ...
Opens in a new windowSunset Beach Inn
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More 4 star hotels in Sanibel

5 star hotels in Sanibel

Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

1451 Middle Gulf Drive Sanibel FL
$498 nightly
The price is $555 total per night from Jun 14 to Jun 15
$555 total
Jun 14 - Jun 15
Total with taxes and fees
8.6/10 Excellent! (2,654 reviews)

Sanibel Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Sanibel luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Sanibel to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Sanibel will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Sanibel, and plan your next opulent escape.


Sanibel hotels essential information

Accommodation
2,106 hotels
Lowest Price
$229
Highest Price
$555
Popular hotels
Sundial Beach Resort & Spa, Seaside Inn, Sunset Beach Inn, Anchor Inn and Cottages, West Wind Inn, Kona Kai Motel, Sanibel Inn, Island Inn

Popular Luxury Stays in Sanibel

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