Book Hotels in San Luis, AZ

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Top San Luis hotels

Little Casita, Big Comfort! Minutes from the border.

Little Casita, Big Comfort! Minutes from the border.

San Luis AZ
This vacation home features laundry facilities.
Amazing Peace
"I truly enjoyed staying here and would recommend this house for anyone staying in the San Luis or Yuma area. Peaceful and Quiet."

Reviewed on Dec 1, 2022

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Opens in a new windowLittle Casita, Big Comfort! Minutes from the border.
Extended Stay America Premier Suites - Yuma

Extended Stay America Premier Suites - Yuma

2.5 out of 5
550 South Rio Vista Dr Yuma AZ
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $116 total per night from Oct 29 to Oct 30
$116 total
Oct 29 - Oct 30
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like on-the-go breakfast and WiFi in public ...
"Our stay was comfortable and staff was friendly"

Reviewed on Oct 27, 2026

Opens in a new windowExtended Stay America Premier Suites - Yuma
Motel 6 Yuma, AZ - East

Motel 6 Yuma, AZ - East

2 out of 5
1445 E 16th St Yuma AZ
Fully refundableReserve now, pay when you stay
$48 nightly
The price is $53 total per night from Nov 16 to Nov 17
$53 total
Nov 16 - Nov 17
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this motel. WiFi in public areas is free. A terrace and a snack bar/deli are also ...
"Okay Great"

Reviewed on Oct 27, 2026

Opens in a new windowMotel 6 Yuma, AZ - East
Super 8 by Wyndham Yuma

Super 8 by Wyndham Yuma

2 out of 5
1688 S Riley Ave Yuma AZ
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $60 total per night from Nov 6 to Nov 7
$60 total
Nov 6 - Nov 7
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like on-the-go breakfast and WiFi in ...
"Rooms were clean. Only issue was their plumbing. Changed rooms due to shower faucet leaking. Was moved to another room to have the same problem. Shower did not have adequate pressure, only hot water. During showering, water pressure went to none."

Reviewed on Oct 27, 2026

Opens in a new windowSuper 8 by Wyndham Yuma
Yuma Inn & Suites

Yuma Inn & Suites

2.5 out of 5
1550 S Castle Dome Ave Yuma AZ
Fully refundable
$81 nightly
The price is $90 total per night from Nov 28 to Nov 29
$90 total
Nov 28 - Nov 29
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"It was worn down some. The hot tub was out of Order but the pool was great. Huge actually. The place just needs some love and serious dusting and decobwebbingb in the lobby."

Reviewed on Oct 28, 2026

Opens in a new windowYuma Inn & Suites
La Fuente Inn & Suites

La Fuente Inn & Suites

3 out of 5
1513 E 16th St Yuma AZ
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $117 total per night from Nov 27 to Nov 28
$117 total
Nov 27 - Nov 28
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
Opens in a new windowLa Fuente Inn & Suites
Best Western Yuma Mall Hotel & Suites

Best Western Yuma Mall Hotel & Suites

3 out of 5
1450 S Castle Dome Ave Yuma AZ
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $100 total per night from Nov 1 to Nov 2
$100 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowBest Western Yuma Mall Hotel & Suites
Radisson Hotel Yuma

Radisson Hotel Yuma

3.5 out of 5
1501 S Redondo Center Drive Yuma AZ
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $121 total per night from Nov 15 to Nov 16
$121 total
Nov 15 - Nov 16
Total with taxes and fees
2 hot tubs, an outdoor pool, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, ...
Opens in a new windowRadisson Hotel Yuma
Quality Inn & Suites Yuma

Quality Inn & Suites Yuma

2.5 out of 5
1691 S Riley Ave Yuma AZ
Fully refundable
$80 nightly
The price is $88 total per night from Nov 6 to Nov 7
$88 total
Nov 6 - Nov 7
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
Opens in a new windowQuality Inn & Suites Yuma
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See all available properties in San Luis
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in San Luis?
Family trips are where you make the best memories, but traveling with youngsters can be difficult. These kid-friendly San Luis hotels come with perks that aim to keep young and old alike relaxed and happy: Unpack your bags at Pet-Friendly San Luis Abode ~ 22 Miles to Yuma!. It comes with a travel crib, a firepit and a knack for making families feel welcome. Also look into Little Casita, Big Comfort! Minutes from the border.. It comes with internet access, clothes washing facilities and ample opportunities to hang out together.
Where can I find cheap hotels in San Luis?
At Travelocity you'll find really nice hotels in San Luis at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near San Luis rather than in San Luis. We may find you even better rates, too.
How do I find the best San Luis hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in San Luis then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in San Luis?
The cheapest hotel in San Luis is $53. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in San Luis?
There are 276 hotels in San Luis on Travelocity.
What are the best hotels in San Luis?
San Luis has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in San Luis for you!
When is the best time to visit San Luis?
If you want the joy of a fun-filled trip in peak season, visit San Luis during January, February and March. If you'd prefer the peace of off-season, book a stay during quieter months, such as June, July and December.
When is the cheapest time to stay in San Luis?
Based on historic data is usually the cheapest month to visit San Luis. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in San Luis?
There are multiple hotels in San Luis that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to San Luis. We have plenty of kid-friendly hotels in San Luis to choose from on Travelocity!
Why book a hotel in San Luis through Travelocity?
Because we have the top hotels in San Luis! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in San Luis on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent San Luis hotel reviews by fellow wanderers

Yuma Inn & Suites

Yuma Inn & Suites

5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"It was worn down some. The hot tub was out of Order but the pool was great. Huge actually. The place just needs some love and serious dusting and decobwebbingb in the lobby."
A verified traveler stayed at Yuma Inn & Suites
Yuma Inn & Suites

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