Book Hotels in San Luis, AZ

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top San Luis hotels

La Fuente Inn & Suites

La Fuente Inn & Suites

3 out of 5
1513 E 16th St, Yuma, AZ
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $109 total per night from Jul 25 to Jul 26
$109 total
Jul 25 - Jul 26
Total includes taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
Yuma La Fuente Inn & Suites Visit
"We REALLY enjoyed our stay at the La Fuente Inn & Suites. The staff was FANTASTIC! Very friendly, very professional and very welcoming. They ALL went out of their way to make sure that our stay was comfortable and Plesant."

Reviewed on Jul 19, 2025

La Fuente Inn & Suites
Radisson Hotel Yuma

Radisson Hotel Yuma

3.5 out of 5
1501 S Redondo Center Drive, Yuma, AZ
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $107 total per night from Aug 10 to Aug 11
$107 total
Aug 10 - Aug 11
Total includes taxes and fees
2 hot tubs, an outdoor pool, and an indoor pool are all featured at this eco-certified hotel. Traveling on business? Take advantage of the 24-hour business center, ...
If in Yuma it’s a must stay!
"Great all the way around! As a full time traveler you can only hope a few places are this good. Safe location, clean room, no drama and it was exactly as advertised. Front desk was very welcoming. Having just spent the week on the road this was great."

Reviewed on Jul 22, 2025

Radisson Hotel Yuma
Wingate by Wyndham Yuma

Wingate by Wyndham Yuma

2.5 out of 5
1760 Sunridge Dr, Yuma, AZ
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $81 total per night from Aug 16 to Aug 17
$81 total
Aug 16 - Aug 17
Total includes taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
"This is a great little get away spot if you’re passing through or will be in Yuma a few days. It’s close to just about everything!"

Reviewed on Jul 14, 2025

Wingate by Wyndham Yuma
Quality Inn & Suites Yuma

Quality Inn & Suites Yuma

2.5 out of 5
1691 S Riley Ave, Yuma, AZ
Fully refundableReserve now, pay when you stay
$50 nightly
The price is $55 total per night from Jul 27 to Jul 28
$55 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. Free WiFi in public areas, ...
"Friendly staff."

Reviewed on Jul 22, 2025

Quality Inn & Suites Yuma
Historic Coronado Motor Hotel by OYO

Historic Coronado Motor Hotel by OYO

2.5 out of 5
233 S 4th Ave, Yuma, AZ
Fully refundable
$71 nightly
The price is $78 total per night from Jul 25 to Jul 26
$78 total
Jul 25 - Jul 26
Total includes taxes and fees
This hotel features an outdoor pool and a gym. Enjoy the hot tub and perks like free self parking and free WiFi. The front desk is staffed around-the-clock and ...
"Classic older Motel easy access"

Reviewed on Jun 25, 2025

Historic Coronado Motor Hotel by OYO
Motel 6 Yuma, AZ - East

Motel 6 Yuma, AZ - East

2 out of 5
1445 E 16th St, Yuma, AZ
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $63 total per night from Jul 25 to Jul 26
$63 total
Jul 25 - Jul 26
Total includes taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this motel. WiFi in public areas is free. A terrace and a snack bar/deli are also ...
"I come for dental work in the area and decidedly stay at Motel 6 each time. Honestly, it's just a super friendly, safe, and convenient location (from the airport), as well as price! The staff is always available, even past midnight, and the room cleaning is available every day - whether you want ..."

Reviewed on Jul 23, 2025

Motel 6 Yuma, AZ - East
Howard Johnson by Wyndham Yuma

Howard Johnson by Wyndham Yuma

2 out of 5
3181 S 4th Ave, Yuma, AZ
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $65 total per night from Jul 26 to Jul 27
$65 total
Jul 26 - Jul 27
Total includes taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Good place to spend the night"

Reviewed on Jul 20, 2025

Howard Johnson by Wyndham Yuma
Best Western Yuma Mall Hotel & Suites

Best Western Yuma Mall Hotel & Suites

3 out of 5
1450 S Castle Dome Ave, Yuma, AZ
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $76 total per night from Aug 1 to Aug 2
$76 total
Aug 1 - Aug 2
Total includes taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"The rooms are so comfortable, clean, and pretty!! The property is very well maintained, and the staff are extremely helpful and friendly!"

Reviewed on Jul 9, 2025

Best Western Yuma Mall Hotel & Suites
Shilo Inn Hotel & Suites - Yuma

Shilo Inn Hotel & Suites - Yuma

2.5 out of 5
1550 S Castle Dome Ave, Yuma, AZ
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $93 total per night from Jul 25 to Jul 26
$93 total
Jul 25 - Jul 26
Total includes taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Recommend 100%
"The pool was clean the rooms were clean. It was quiet and peaceful. Staff were friendly. Definitely will recommend and stay again."

Reviewed on Jul 15, 2025

Shilo Inn Hotel & Suites - Yuma
Don't see what you're looking for?
See all available properties in San Luis
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in San Luis?
Family trips are where you make the best memories, but traveling with youngsters can be difficult. These kid-friendly San Luis hotels come with perks that aim to keep young and old alike relaxed and happy: Unpack your bags at Pet-Friendly San Luis Abode ~ 22 Miles to Yuma!. It comes with a travel crib, a firepit and a knack for making families feel welcome. Also look into Little Casita, Big Comfort! Minutes from the border.. It comes with internet access, clothes washing facilities and ample opportunities to hang out together.
Where can I find cheap hotels in San Luis?
At Travelocity you'll find really nice hotels in San Luis at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near San Luis rather than in San Luis. We may find you even better rates, too.
How do I find the best San Luis hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in San Luis then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in San Luis?
The cheapest hotel in San Luis is $55. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in San Luis?
There are 206 hotels in San Luis on Travelocity.
What are the best hotels in San Luis?
San Luis has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in San Luis for you!
When is the best time to visit San Luis?
If you want the joy of a fun-filled trip in peak season, visit San Luis during January, February and March. If you'd prefer the peace of off-season, book a stay during quieter months, such as June, July and December.
When is the cheapest time to stay in San Luis?
Based on historic data is usually the cheapest month to visit San Luis. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in San Luis?
There are multiple hotels in San Luis that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to San Luis. We have plenty of kid-friendly hotels in San Luis to choose from on Travelocity!
Why book a hotel in San Luis through Travelocity?
Because we have the top hotels in San Luis! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in San Luis on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent San Luis hotel reviews by fellow wanderers

Motel 6 Yuma, AZ - East

Motel 6 Yuma, AZ - East

5 out of 5
Posted 1 day ago
Travelocity Verified Review
"I come for dental work in the area and decidedly stay at Motel 6 each time. Honestly, it's just a super friendly, safe, and convenient location (from the airport), as well as price! The staff is always available, even past midnight, and the room cleaning is available every day - whether you want it or not 😂 I would like to offer a gentle suggestion to Motel 6 in this regard, that it would be better to have "do not disturb" & "do not clean" door tags available for guests to set on their doorknobs, that cleaning staff could pay attention to. Otherwise, it is always a perfectly fine experience with Motel 6 at this location! Thanks for providing all of the hot water I needed 🙂🙏"
A verified traveler stayed at Motel 6 Yuma, AZ - East
Motel 6 Yuma, AZ - East
Explore More Ways to Travel with Travelocity

Explore More Ways to Travel with Travelocity