Book Hotels in Río Sereno

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Río Sereno hotels

Ecoresort:  We are Panamas leading honey producer and  butterfly exhibit.

Ecoresort: We are Panamas leading honey producer and butterfly exhibit.

Boquete Provincia de Chiriquí
A terrace and a garden are available at this vacation home.
"Little cottages in an unbelievable garden setting. Communications with Emily were clear and she was always helpful. Lovely breakfast!"

Reviewed on Apr 8, 2026

Opens in a new windowEcoresort: We are Panamas leading honey producer and butterfly exhibit.
Risco de Hugo

Risco de Hugo

2 out of 5
2 Volcancito Road Boquete Chiriquí Province
Luggage storage is available at this lodge. Take advantage of the free self parking.
"This property is beautiful. Is a space to relax. If you are a couple and have friends, you want them there so you can share a awesome time. The view and the weather is awesome. I will return soon that's how good the experience was."

Reviewed on Apr 1, 2026

Opens in a new windowRisco de Hugo
Los Brezos Boutique Hotel

Los Brezos Boutique Hotel

3.5 out of 5
Calle Tercera Norte Volcan Chiriquí
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $131 total per night from Jun 10 to Jun 11
$131 total
Jun 10 - Jun 11
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
"I've learned to be cynical about hotels, but Hotel Los Brezos was a very pleasant surprise. The room wasn't big, but very nice, with excellent maid service. The restaurant was great, and we're picky. We'll be back in Volcan, and we won't dare stay anywhere else."

Reviewed on Apr 2, 2026

Opens in a new windowLos Brezos Boutique Hotel
Hostal Victoria Volcán Chiriquí S. A.

Hostal Victoria Volcán Chiriquí S. A.

2 out of 5
Volcan Chiriquí Nueva California Chiriquí
Fully refundableReserve now, pay when you stay
$41 nightly
The price is $46 total per night from Jun 12 to Jun 13
$46 total
Jun 12 - Jun 13
Total with taxes and fees
Free self parking is available and the hostal's front desk is staffed around-the-clock. WiFi in public areas is free. A convenience store is also provided.
"Room was clean. No breakfast served but coffee in the reception area where there are also breakfast snacks available for sale. The staff was amazing!"

Reviewed on Mar 20, 2026

Opens in a new windowHostal Victoria Volcán Chiriquí S. A.
Hotel Dos Rios

Hotel Dos Rios

3 out of 5
43, Nueva California Nueva California
$86 nightly
The price is $94 total per night from Jun 8 to Jun 9
$94 total
Jun 8 - Jun 9
Total with taxes and fees
A restaurant, free self parking, and a terrace are among this hotel's amenities. Guests will appreciate free perks like full breakfast and WiFi in public areas. ...
"Great staff, really enjoyed each and everyone, but one must remember where in the world they are. The hotel is on well tended gardens, nothing spectacular, but remember where you are. Unfortunately they need to upgrade, maybe it’s not possible, who am I to assume? One, two days max is enough, we ..."

Reviewed on May 17, 2026

Opens in a new windowHotel Dos Rios
Casa Grande Bambito Resort

Casa Grande Bambito Resort

4 out of 5
Calle El Manantial Paso Ancho Chiriqui
This hotel features a restaurant, a hot tub, and a bar/lounge. There's fun for all ages with a playground and an arcade/game room, and barbecue grills are available ...
"We went for 3 days to the Junior Suite 1. First day there was a wedding. Noise all night long When we got there, the TV did not work. Wifi slow and sometimes it went down. Antes on the sink, the staff told me that "usually happens". No mosquito screen. You need to sleep with windows opens, which ..."

Reviewed on Jan 15, 2025

Opens in a new windowCasa Grande Bambito Resort
Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals

Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals

3 out of 5
Volcan, Via Cerro Punta Volcan Chiriqui
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $125 total per night from Jun 10 to Jun 11
$125 total
Jun 10 - Jun 11
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Families will appreciate the playground and onsite laundry facilities. Enjoy the outdoor ...
"I really like the restaurant attendants the were very helpful"

Reviewed on May 25, 2026

Opens in a new windowHotel Faranda Bambito Chiriquí, a member of Radisson Individuals
Hotel Finca Lerida

Hotel Finca Lerida

3 out of 5
Alto Quiel Los Naranjos Chiriqui
$132 nightly
The price is $145 total per night from Jun 15 to Jun 16
$145 total
Jun 15 - Jun 16
Total with taxes and fees
A restaurant, free self parking, and a 24-hour front desk are among this hotel's amenities. Guests will appreciate free perks like continental breakfast and ...
Opens in a new windowHotel Finca Lerida
Los Quetzales Ecolodge & Spa

Los Quetzales Ecolodge & Spa

3 out of 5
Guadalupe Cerro Punta Chiriqui
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $118 total per night from Jun 8 to Jun 9
$118 total
Jun 8 - Jun 9
Total with taxes and fees
A full-service spa and A 24-hour gym are featured at this smoke-free lodge. Guests will appreciate free perks like free self parking and WiFi in public areas. ...
Opens in a new windowLos Quetzales Ecolodge & Spa
Don't see what you're looking for?
See all available properties in Río Sereno
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Río Sereno hotel reviews by fellow wanderers