Explore 2 Luxury Hotels in Pythagorio

Name: Doryssa Seaside Resort
Price range: $219 total
Rating: 8.6

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Best Luxury Hotels in Pythagorio

Proteas Blu Resort - Adults Only

Pythagorion, Samos, Samos Island

Fully refundableReserve now, pay when you stay

$188 nightly

$224 total

Oct 1 - Oct 2

Total with taxes and fees

This luxury hotel features a private beach, a full-service spa, and 3 restaurants. Relax with sun loungers and beach umbrellas, and cool off with a drink at ...

9.4/10 Exceptional! (85 reviews)

"Perfect"

Reviewed on Sep 23, 2025

Doryssa Seaside Resort

Pythagoreiou-Choras, Samos, Samos Island

Fully refundableReserve now, pay when you stay

$183 nightly

$219 total

Oct 6 - Oct 7

Total with taxes and fees

A full-service spa, 2 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Enjoy beachfront dining and relax with sun loungers and beach ...

8.6/10 Excellent! (150 reviews)

Clean and comfortable

"Only really used the hotel for getting ready and to sleep, so can’t really comment too much. Hotel was comfortable and clean. Breakfast was good and it has a nice pool area with big comfy sunbeds. We were only there for 3 days, so spent most of our time sightseeing."

Reviewed on Jun 28, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

5 star hotels in Pythagorio

Casa Cook Samos

Potokaki, Pythagorion, Samos

$220 nightly

$258 total

Oct 5 - Oct 6

Total with taxes and fees

9.4/10 Exceptional! (91 reviews)

Pythagorio Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Pythagorio luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Pythagorio to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Pythagorio will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Pythagorio, and plan your next opulent escape.