Explore 5 Luxury Hotels in Odessa

Name: Hilton Garden Inn Odessa
Price range: $93 total

Best Luxury Hotels in Odessa

Residence Inn Odessa

7261 Tres Hermanas Blvd Odessa TX

Fully refundableReserve now, pay when you stay

$89 nightly

$102 total

Apr 18 - Apr 19

Total with taxes and fees

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...

9.2/10 Wonderful! (758 reviews)

The staff were extremely helpful and friendly. The room was very clean and comfortable. The facility inside and outside were clean and inviting and gave a sense of security.

Reviewed on Mar 23, 2026

MCM Elegante Hotel and Conference Center Odessa

5200 E. University Blvd. Odessa TX

Fully refundableReserve now, pay when you stay

$121 nightly

$140 total

Apr 17 - Apr 18

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...

9/10 Wonderful! (1,010 reviews)

Clean room and staff was great. Great location.

Reviewed on Apr 10, 2026

Ramada by Wyndham Odessa Near University of Texas Permian

3001 E Business Loop 20 Odessa TX

Fully refundableReserve now, pay when you stay

$72 nightly

$83 total

Apr 19 - Apr 20

Total with taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...

6.8/10 (1,002 reviews)

The property is old and a bit dilapidated, but the bed was clean. The only problem with the room was that the floor seemed sticky and hadn't been cleaned adequately. Other than this, the room was quiet and comfortable.

Reviewed on Apr 10, 2026

Howard Johnson by Wyndham Odessa TX

2925 E. Business Loop 20 Odessa TX

Fully refundableReserve now, pay when you stay

$51 nightly

$59 total

May 3 - May 4

Total with taxes and fees

An outdoor pool, free self parking, and laundry facilities are featured at this motel. Guests will appreciate free perks like buffet breakfast and WiFi in public ...

6.4/10 (1,007 reviews)

Friendly staff

Reviewed on Apr 7, 2026

Hilton Garden Inn Odessa

5221 Jbs Pkwy Odessa TX

Fully refundableReserve now, pay when you stay

$81 nightly

$93 total

Apr 19 - Apr 20

Total with taxes and fees

This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

5 star hotels in Odessa

The Modern Midland Flats

516 North Loop 250 West Midland TX

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5/10 (10 reviews)

Odessa Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Odessa luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Odessa to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Odessa will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Odessa, and plan your next opulent escape.

Odessa hotels essential information

Accommodation	449 hotels
Lowest Price	$59
Highest Price	$140
Popular hotels	MCM Elegante Hotel and Conference Center Odessa, Howard Johnson by Wyndham Odessa TX, Ramada by Wyndham Odessa Near University of Texas Permian, Hilton Garden Inn Odessa, Residence Inn Odessa