Explore 49 Luxury Hotels in North Central Florida

Name: Baymont By Wyndham Gainesville I-75
Price range: $81 total
Rating: 5.2

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Best Luxury Hotels in North Central Florida

Best Western Waldo Inn and Suites

17230 Ne Us Highway 301 Waldo FL

Fully refundableReserve now, pay when you stay

$93 nightly

$105 total

Mar 19 - Mar 20

Total with taxes and fees

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...

8.8/10 Excellent! (978 reviews)

The shower needs to be steam cleaned. My husband said on the way home he would have to bring a cleaning solution to stay there again. I do not believe it is from lack of cleaning, showers often need a refresh after many many uses. Take into consideration there is no fresh ventilation in there, that ...

Reviewed on Mar 11, 2026

Americas Best Value Inn Lake City

3835 West US Highway 90 Lake City FL

Fully refundableReserve now, pay when you stay

$67 nightly

$76 total

Mar 15 - Mar 16

Total with taxes and fees

An outdoor pool is featured at this motel, along with free self parking. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. ...

8.6/10 Excellent! (1,002 reviews)

Clean room, hot shower. Beds were meh, property slightly rundown, but for the $$ 3.5 stars

Reviewed on Mar 10, 2026

Driftwood Inn

2764 W US Hwy 90 Lake City FL

Fully refundable

$63 nightly

$71 total

Mar 29 - Mar 30

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...

7.8/10 Good! (777 reviews)

Owner was very nice and room was super clean. Would stay there again.

Reviewed on Feb 28, 2026

Palms Garden Inn

14113 S. US Hwy 441 Lake City FL

Fully refundableReserve now, pay when you stay

$65 nightly

$73 total

Mar 15 - Mar 16

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Express check-out and laundry facilities are also provided.

7.4/10 Good! (593 reviews)

Basic room good for a short term stay. Stayed two nights room was not cleaned. Outside door on room not exactly sealed tight. One must consider the rate . For the money decent value.

Reviewed on Mar 11, 2026

Gainesville Lodge

413 West University Ave Gainesville FL

$87 nightly

$98 total

Mar 30 - Mar 31

Total with taxes and fees

Free WiFi in public areas is available at this motel. Take advantage of the free self parking.

6.6/10 (7 reviews)

Thank for a great stay. So much better than the usual corporate hotels. Staff were very helpful. Room was very nice.

Reviewed on Mar 11, 2026

WoodSpring Suites Gainesville I-75

5505 SW 41st Blvd Gainesville FL

Fully refundableReserve now, pay when you stay

$63 nightly

$71 total

Mar 15 - Mar 16

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-out. The front ...

6.2/10 (1,000 reviews)

The staff was mostly absent. No I've machine. But the room was clean. One of the beds was broken.

Reviewed on Mar 10, 2026

Days Inn by Wyndham Gainesville University I-75

920 Nw 69th Ter Gainesville FL

Fully refundableReserve now, pay when you stay

$64 nightly

$72 total

Mar 15 - Mar 16

Total with taxes and fees

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...

5.6/10 (1,002 reviews)

good clean A1

Reviewed on Mar 11, 2026

Baymont By Wyndham Gainesville I-75

6901 NW 4th Boulevard Gainesville FL

Fully refundableReserve now, pay when you stay

$72 nightly

$81 total

Mar 15 - Mar 16

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling for business? Take advantage of the business center, laundry ...

5.2/10 (1,000 reviews)

All that was good but need to pay more attention to pot being smoked all over the motel

Reviewed on Mar 9, 2026

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5 star hotels in North Central Florida

The Equestrian Hotel

8510 NW 17th Lane Ocala FL

$280 nightly

$312 total

Mar 29 - Mar 30

Total with taxes and fees

9.8/10 Exceptional! (615 reviews)

North Central Florida Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the North Central Florida luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in North Central Florida to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in North Central Florida will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in North Central Florida, and plan your next opulent escape.

North Central Florida hotels essential information

Accommodation	2,692 hotels
Lowest Price	$71
Highest Price	$312
Popular hotels	Baymont By Wyndham Gainesville I-75, Palms Garden Inn, Americas Best Value Inn Lake City, Driftwood Inn, Days Inn by Wyndham Gainesville University I-75, WoodSpring Suites Gainesville I-75, Best Western Waldo Inn and Suites, Gainesville Lodge

Popular Luxury Stays in North Central Florida

5 Stars Luxury stays in North Central Florida

Luxury stays in North Central Florida with spa

Recent North Central Florida Hotel Reviews By Fellow Wanderers

Days Inn by Wyndham Ocala North

5 out of 5

Posted 8 hours ago

Travelocity Verified Review

"Perfect for where we were trying to be close to. Nice room close to interstate and gas station "

A verified traveler stayed at Days Inn by Wyndham Ocala North

Quality Inn & Suites Ocala I-75

3 out of 5

Posted 17 hours ago

Travelocity Verified Review

"The main problem was that the sheets on the bed had not been cleaned. The bed was made but the bedding was obviously dirty, stains from dirt and possibly make-up on the comforter and sheets. We pulled the blankets back and there were curly black hairs all over the bed. I told the lady at the desk and she personally came down and replaced the bedding. So her quick response was appreciated. She said she would give us an email to send pictures to but we never got the email. Hotel is dated. They have tried to update some things but some things are still very old. The fiberglass tub was obviously old, looks dirty even though it appeared to have been cleaned. Mold under the clear caps of the built in shampoo bottles. Toilet seat lid had broken bolt so it would not stay in place. Not a great experience. Due to the time of year and scarcity of rooms available, the cost of the room was pretty expensive, costing over $200. "

A verified traveler stayed at Quality Inn & Suites Ocala I-75