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Top Mytilene hotels

Elies Residences

Elies Residences

No Name, Lesvos, Lesvos
$113 nightly
The price is $125 total per night from Nov 6 to Nov 7
$125 total
Nov 6 - Nov 7
Total with taxes and fees
An outdoor pool, free parking, and laundry facilities are featured at this villa. Guests will appreciate free perks like free self parking and WiFi in public ...
The sea view pool and the landscaping were so impressive and tranquil. Wish we could have stayed longer. The Molivos apartment was very nice and relaxing with 2 bedrooms , 2 bathrooms, 2 verandas, kitchen. LR, communal pool, 2 extra sunbeds on the grass under a tree, and parking. Perfect apartment ...

Reviewed on Jun 23, 2025

Opens in a new windowElies Residences
Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel

4 out of 5
7, Skra str, Hatzidimitriou Park, Mytilene, Lesvos
Fully refundableReserve now, pay when you stay
A full-service spa and a hot tub are featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public areas and free internet ...
Beautiful hotel e great staff and service. Perfect location. Great breakfast. My go to! I will pay the two night minimum even if I stay one night!

Reviewed on Oct 3, 2025

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Opens in a new windowTheofilos Paradise Boutique Hotel
ISSA Lesvos

ISSA Lesvos

15 Agiou Efstratiou, Lesvos, Lesvos
$115 nightly
The price is $128 total per night from Nov 12 to Nov 13
$128 total
Nov 12 - Nov 13
Total with taxes and fees
Free WiFi in public areas, a communal living room, and luggage storage are available at this hotel. Locker space, laundry facilities, and concierge services ...
I arrived for a short trip to ISSA and it was a real memorable experience. the room super clean, very supportive check in and the front office team (all of them) are extremly friendly and helpful. I loved their special care and attention during my short visit. I'd always come back....

Reviewed on Jul 1, 2025

Opens in a new windowISSA Lesvos
Hotel Lesvion

Hotel Lesvion

3 out of 5
P. Kountourioti 27A, Lesvos
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public ...
Great room, excellent staff and amazing breakfast.

Reviewed on Oct 28, 2025

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Opens in a new windowHotel Lesvion
Elysion Hotel

Elysion Hotel

5 out of 5
Neapoli, Mytilene, Lesvos, Lesvos Island
This hotel features 2 restaurants, 3 outdoor tennis courts, and an outdoor pool. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like buffet ...
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Reviewed on Dec 16, 2024

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Opens in a new windowElysion Hotel
Heliotrope The Studios

Heliotrope The Studios

Kyparrision 8A Street, Lesvos, Lesvos
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $84 total per night from Dec 6 to Dec 7
$84 total
Dec 6 - Dec 7
Total with taxes and fees
Free WiFi in public areas, a terrace, and a garden are available at this guesthouse. Dry cleaning, luggage storage, and laundry facilities are also on ...
Staff was friendly especially Maria went out of her way to assist. The place was having some renovations done new sensor lighting and furniture cabinet upgrades. All in all the stay was pleasant and comfortable.

Reviewed on Jun 13, 2024

Opens in a new windowHeliotrope The Studios
Heliotrope Hotels

Heliotrope Hotels

4 out of 5
Varia, Mytilene, Lesvos, Lesvos Island
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $97 total per night from Nov 8 to Nov 9
$97 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel features 2 restaurants, 4 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
Stayed here both last year and this summer. Very convenient location between airport and city centre. There is a bus stop right across the hotel but taxi is also very affordable. They have a nice buffet breakfast and rooms are very clean. Friendly staff as well.

Reviewed on Aug 26, 2025

Opens in a new windowHeliotrope Hotels
Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat

5 out of 5
Agrilia, Lesvos
Fully refundableReserve now, pay when you stay
A full-service spa, 5 restaurants, and 3 indoor pools are all featured at this luxury hotel. Traveling on business? Take advantage of the business center and ...
I booked a junior suite. The description does not match the room. The room was to have a balcony and it does not. It was a basic room of 30 square metres with two single beds pushed together and a chair and small table. The service was terrible. The person at teh front desk in the morning was rude ...

Reviewed on Aug 13, 2025

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Opens in a new windowMythical Coast Wellness Retreat
The Loriet

The Loriet

4 out of 5
Vareia, Mitilene, Lesvos, Lesvos Island
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $75 total per night from Nov 6 to Nov 7
$75 total
Nov 6 - Nov 7
Total with taxes and fees
This aparthotel features a restaurant, an outdoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Relax with ...
Perfect hotel! Very authentic and beautiful. The only negative I would give is the lighting and the steps in the room.

Reviewed on Aug 8, 2025

Opens in a new windowThe Loriet
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Mytilene?
Take some of the trials out of traveling with kids by staying in a family-friendly Mytilene hotel. From fun amenities to services that bring a smile, these properties come with perks that'll help make your trip an effortless one: Your entourage will enjoy their time at Sofies Choice Mytilini. Free WiFi and clothes washing facilities are among the things that help make this hotel a winner. Blue Sea is also a great choice. After a big day of exploring, come home to your comfortable room and amenities like room service and front desk services.
Where can I find cheap hotels in Mytilene?
At Travelocity you'll find really nice hotels in Mytilene at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Mytilene rather than in Mytilene. We may find you even better rates, too.
How do I find the best Mytilene hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Mytilene then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Mytilene?
The cheapest hotel in Mytilene is $75. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Mytilene?
There are 166 hotels in Mytilene on Travelocity.
What are the best hotels in Mytilene?
Mytilene has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Mytilene for you!
When is the best time to visit Mytilene?
If you want the joy of a fun-filled trip in peak season, visit Mytilene during January, July and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as February, November and December.
When is the cheapest time to stay in Mytilene?
Based on historic data is usually the cheapest month to visit Mytilene. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Mytilene?
There are multiple hotels in Mytilene that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Mytilene. We have plenty of kid-friendly hotels in Mytilene to choose from on Travelocity!
Why book a hotel in Mytilene through Travelocity?
Because we have the top hotels in Mytilene! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Mytilene on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Mytilene hotel reviews by fellow wanderers

Hotel Lesvion

Hotel Lesvion

5 out of 5
Posted 8 days ago
Travelocity Verified Review
"Great room, excellent staff and amazing breakfast."
A verified traveler stayed at Hotel Lesvion
Hotel Lesvion

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