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Price found within the past 48 hours. Click for updated prices.
Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL

2.5 out of 5
Price was $561, price is now $535 per person
$535
per person
Oct 22 - Oct 25
found 24 hours ago
Roundtrip flight included
San Diego (SAN) to Veterans Airport of Southern Illinois (MWA)
This hotel features free WiFi in public areas, free newspapers, and free self parking. Enjoy the free full breakfast each morning. Staff at the 24-hour front desk can provide around-the-clock assistance.
Days Inn by Wyndham Mount Vernon

Days Inn by Wyndham Mount Vernon

2 out of 5
Price was $574, price is now $549 per person
$549
per person
Oct 22 - Oct 25
found 24 hours ago
Roundtrip flight included
San Diego (SAN) to Veterans Airport of Southern Illinois (MWA)
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 out of 5
Price was $1,002, price is now $988 per person
$988
per person
Oct 22 - Oct 25
found 13 hours ago
Roundtrip flight included
Gainesville (GNV) to Veterans Airport of Southern Illinois (MWA)
A restaurant and an indoor pool are featured at this hotel. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies like self-serve breakfast and free self parking.
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3.5 out of 5
Price was $643, price is now $636 per person
$636
per person
Oct 22 - Oct 25
found 24 hours ago
Roundtrip flight included
San Diego (SAN) to Veterans Airport of Southern Illinois (MWA)
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the 24-hour gym and free perks like buffet breakfast and free self parking.
Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG

2.5 out of 5
Price was $617, price is now $611 per person
$611
per person
Oct 22 - Oct 25
found 24 hours ago
Roundtrip flight included
San Diego (SAN) to Veterans Airport of Southern Illinois (MWA)
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Top Murphysboro hotels deals

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 out of 5
120 MUDDY MONSTER ROAD Murphysboro IL
$118 nightly
The price is $131 total per night
$131 total
Sep 9 - Sep 10
Total with taxes and fees
A restaurant and an indoor pool are featured at this hotel. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies like self-serve breakfast and free self parking.
Pet Friendly! Couples Retreat in Southern Illinois

Pet Friendly! Couples Retreat in Southern Illinois

Murphysboro IL
$215 nightly
The price is $237 total per night
$237 total
Sep 3 - Sep 4
Total with taxes and fees
Stay at this apartment in Murphysboro. Enjoy patios and an in-room coffeemaker. Popular attractions Kite Hill Vineyards and General John A. Logan Museum are located nearby.
Cabin 2: Lakeside in Murphysboro

Cabin 2: Lakeside in Murphysboro

Murphysboro IL
$221 nightly
The price is $244 total per night
$244 total
Sep 3 - Sep 4
Total with taxes and fees
This cabin features barbecue grills.
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St Marion IL
$90 nightly
The price is $108 total per night
$108 total
Sep 27 - Sep 28
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and free perks like buffet breakfast and free self parking.
Baymont by Wyndham Marion

Baymont by Wyndham Marion

2.5 out of 5
2608 W Main St Marion IL
$87 nightly
The price is $105 total per night
$105 total
Sep 13 - Sep 14
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.
Walker's Bluff Casino Resort

Walker's Bluff Casino Resort

4.5 out of 5
777 Walkers Bluff Way Carterville IL
$117 nightly
The price is $130 total per night
$130 total
Sep 15 - Sep 16
Total with taxes and fees
This luxury resort features a casino, a full-service spa, and 3 restaurants. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Relax with a drink at one of the 3 bars/lounges and enjoy perks like free self parking.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Murphysboro attractions

Lake Murphysboro State Park

8.2/10 (22 reviews)
Explore the star-shaped shoreline of the lake and go hiking, camping, fishing and boating with a backdrop of tree-covered hills.
See properties

Frequently asked questions

How much are vacation packages to Murphysboro?
You'll find an awesome hotel and flight bundle from just $535. With one of our Travelocity vacation packages, a getaway in Murphysboro has never looked so good! Save both time and cash and then start packing that suitcase.
How long should my Murphysboro vacation be?
Many visitors pack their suitcase and escape to Murphysboro for an average of 2 nights. That gives you an idea of time frames, but don't be limited by it. Whether you only stay a few nights to see the main sights or linger a while to experience this place like a local, an unforgettable journey awaits.
Where can I get the best vacation package deals for Murphysboro?
You'll come across a terrific selection of Murphysboro package deals on Travelocity. With as many as 400 air carriers and 1,000,000 properties worldwide, putting together your ideal escape will be a breeze.
Why should I book my Murphysboro vacation package via Travelocity?
We offer 24/7 support, first-rate service and a Price Match Guarantee. Travel is all about the journey — and we have alluring destinations for you to journey to in all four corners of the globe. Roam with us and your bank balance will thank you for it.
Can I save money on my Murphysboro car rental if I combine it with hotels and flights?
You certainly can — bundle your flight, car and hotel into a Murphysboro vacation package and you can save a handsome sum. With so much to uncover in Murphysboro, having your own wheels will come in handy. Once you've buckled up, put the stereo on and cruise toward Busch Stadium, a must-see attraction around 75 mi from Murphysboro.
Which airport is best for Murphysboro?
Chances are you'll be landing at Williamson County Regional Airport (MWA), situated 17 mi east of downtown Murphysboro. Cape Girardeau Municipal Airport (CGI) (40 mi away from central Murphysboro) and Barkley Regional Airport (PAH) (60 mi away from central Murphysboro) are other choices.
What is there to do in Murphysboro?
There is a certain kind of magic as you stroll through the streets of Murphysboro. Lake Murphysboro State Park and Hickory Ridge Public Golf Center are just two landmarks that lure visitors to this fantastic city, so add them to your itinerary.
Where should I stay when visiting Murphysboro?
Many people stay at the Holiday Inn Express & Suites Murphysboro - Carbondale, an IHG Hotel. It's sure to be a good base for your Murphysboro escape.

Photos of local treasures

Browse Murphysboro vacation photos for more inspiration

A sunset over a river with a bridge, surrounded by sparse trees and dry grass.
A forest with a moss-covered fallen tree, a rocky stream bed, and dense foliage.
A wooden bridge over a calm river, surrounded by trees with autumn foliage.
A sign indicating Pine Circle Picnic Area, Little Lake, and Campgrounds.
A sign for Lake Murphysboro State Park with a caution sign and the Illinois Department of Natural Resources logo.