Book Hotels in Mission Hill, SD
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Top Mission Hill hotels

Fairfield Inn & Suites by Marriott Yankton
508 WEST 21ST STREET, Yankton, SD
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $164 total per night from Nov 9 to Nov 10
$164 total
Nov 9 - Nov 10
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public areas. ...
"The front desk stuff was nice ! They greeted you when you came in and were very helpful. At same time breakfast was very poor there was almost nothing to eat. The hotel was brand new and looked good and clean. Outside hotel different story it’s build on Parking lot of a shopping center which was ..."
Reviewed on Sep 27, 2025

Comfort Inn Yankton SD
611 W 23rd Street, Yankton, SD
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $112 total per night from Nov 2 to Nov 3
$112 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies ...
"The staff was friendly and helpful, they let us check-in 1 hour early, they were great with kids, the room was clean except for what looked like a juice stain on the carpet. The heat worked great, it was quiet in the room, and the beds were comfortable. Breakfast had many different options, and the ..."
Reviewed on Oct 16, 2025

Best Western Vermillion Inn
701 W Cherry St, Vermillion, SD
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $105 total per night from Nov 19 to Nov 20
$105 total
Nov 19 - Nov 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. There's a sauna on site, and a 24-hour ...
"x"
Reviewed on Oct 6, 2025

Lewis and Clark Resort
43496 Shore Drive, Yankton, SD
$98 nightly
The price is $104 total per night from Oct 30 to Oct 31
$104 total
Oct 30 - Oct 31
Total with taxes and fees
A marina and a restaurant are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
"nice place"
Reviewed on Oct 11, 2025

Holiday Inn Express Hotel & Suites Vermillion by IHG
1200 N Dakota St, Vermillion, SD
$118 nightly
The price is $130 total per night from Oct 26 to Oct 27
$130 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business center, ...
"Cleanliness was important. A great nights sleep."
Reviewed on Sep 6, 2025

Red Roof Inn Vermillion - U of South Dakota
1208 E Cherry St, Vermillion, SD
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $99 total per night from Oct 21 to Oct 22
$99 total
Oct 21 - Oct 22
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. WiFi in public areas is free. A snack bar/deli is provided and the front desk is staffed ...
"bathtub was clogged."
Reviewed on Oct 13, 2025

Best Western Kelly Inn
1607 E Highway 50, Yankton, SD
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $117 total per night from Oct 27 to Oct 28
$117 total
Oct 27 - Oct 28
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"This was the perfect hotel for my family to stay in for a wedding. We enjoyed the breakfast, pool, and attached restaurant. I would stay there again."
Reviewed on Oct 13, 2025

Yankton Inn
1603 East Highway 50, Yankton, SD
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $92 total per night from Oct 29 to Oct 30
$92 total
Oct 29 - Oct 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
"The room was excellent, air conditioner kept is cool, the shower had great hot water, the beds were really nice."
Reviewed on Oct 15, 2025

Econo Lodge Inn & Suites
2410 Broadway Ave, Yankton, SD
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $85 total per night from Nov 2 to Nov 3
$85 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"The hotel was clean and quiet"
Reviewed on Oct 6, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent Mission Hill hotel reviews by fellow wanderers

Comfort Inn Yankton SD
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"The staff was friendly and helpful, they let us check-in 1 hour early, they were great with kids, the room was clean except for what looked like a juice stain on the carpet. The heat worked great, it was quiet in the room, and the beds were comfortable. Breakfast had many different options, and the area was kept cleaned and stocked. Check-out was simple and easy as well. The hotel is right behind the mall that has hobby lobby, 5 below, and Marshall's, there is a McDonald's a block away and a gas station right up the street. "
A verified traveler stayed at Comfort Inn Yankton SD