Book Hotels in Mission Hill, SD
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Top Mission Hill hotels

Fairfield Inn & Suites by Marriott Yankton
508 WEST 21ST STREET Yankton SD
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $137 total per night from Mar 15 to Mar 16
$137 total
Mar 15 - Mar 16
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public areas. ...
The property was well lit and in excellent condition. The staff was very helpful!
Reviewed on Feb 23, 2026

Lewis and Clark Resort
43496 Shore Drive Yankton SD
$84 nightly
The price is $89 total per night from Mar 8 to Mar 9
$89 total
Mar 8 - Mar 9
Total with taxes and fees
A marina and a restaurant are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
Perfect spot!
Reviewed on Mar 3, 2026

Comfort Inn Yankton SD
611 W 23rd Street Yankton SD
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $107 total per night from Apr 2 to Apr 3
$107 total
Apr 2 - Apr 3
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies ...
We love this hotel!!! Always clean, friendly, and quiet!
Reviewed on Mar 5, 2026

Best Western Vermillion Inn
701 W Cherry St Vermillion SD
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $106 total per night from Mar 8 to Mar 9
$106 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features an indoor pool and a gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. There's a sauna on site, and a 24-hour ...
Room and staff were good but the walls are paper thin. We could hear the people in the next room with no issues.
Reviewed on Feb 27, 2026

Holiday Inn Express Hotel & Suites Vermillion by IHG
1200 N Dakota St Vermillion SD
$118 nightly
The price is $130 total per night from Mar 9 to Mar 10
$130 total
Mar 9 - Mar 10
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business center, ...
The hotel was being rennovated to an extreme that made it difficult. Signage is all on the floors. We were given a different room style than what we reserved (with no discount) that had outlets and blinds that did not work. No sheets or pillows were included for the pull out couch. There was renovation ...
Reviewed on Mar 1, 2026

Best Western Kelly Inn
1607 E Highway 50 Yankton SD
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $106 total per night from Mar 22 to Mar 23
$106 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Everything was pretty good, but the 2nd night was crazy. We didn’t get to bed until midnight, kids were running in the hallway and screaming.
Reviewed on Feb 22, 2026

Red Roof Inn Vermillion - U of South Dakota
1208 E Cherry St Vermillion SD
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $79 total per night from Mar 13 to Mar 14
$79 total
Mar 13 - Mar 14
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like full breakfast and WiFi in public areas. A snack ...
Bathroom needs to be updated. Have stayed in several rooms now and all need plumbing attention in the showers.
Reviewed on Feb 23, 2026

Econo Lodge Inn & Suites Yankton
2410 Broadway Ave Yankton SD
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $71 total per night from Mar 12 to Mar 13
$71 total
Mar 12 - Mar 13
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Good hotel. Clean room, good breakfast, and good rate.
Reviewed on Mar 3, 2026

Holiday Inn Express & Suites Yankton by IHG
2607 Broadway Ave Yankton SD
Fully refundable
$115 nightly
The price is $127 total per night from Apr 2 to Apr 3
$127 total
Apr 2 - Apr 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Mission Hill hotel reviews by fellow wanderers

Comfort Inn Yankton SD
5 out of 5
Posted 17 hours ago
Travelocity Verified Review
"We love this hotel!!! Always clean, friendly, and quiet!"
A verified traveler stayed at Comfort Inn Yankton SD






