Deals on vacations and trips to Mayo

Save when you book Mayo package deals

Choose two or more items and save on your trip:

Top Mayo hotels deals

ECHO Suites Extended Stay by Wyndham Spartanburg

ECHO Suites Extended Stay by Wyndham Spartanburg

2 out of 5
490 W Blackstock Road Spartanburg SC
Free Cancellation
Reserve now, pay when you stay
$73 nightly
The price is $81 total per night
$81 total
Dec 24 - Dec 25
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk can provide around-the-clock assistance.
Pet friendly
Parking included
Spartanburg Marriott

Spartanburg Marriott

3.5 out of 5
299 North Church Street Spartanburg SC
Free Cancellation
Reserve now, pay when you stay
$118 nightly
The price is $131 total per night
$131 total
Dec 24 - Dec 25
Total with taxes and fees
This smoke-free hotel features 3 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and perks like free self parking.
Pool
Parking included
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

2.5 out of 5
458 West Blackstock Road Spartanburg SC
Free Cancellation
Reserve now, pay when you stay
$89 nightly
The price is $99 total per night
$99 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like full breakfast and free self parking.
Pool
Breakfast included
Sleep Inn Spartanburg Southwest

Sleep Inn Spartanburg Southwest

2.5 out of 5
501 South Blackstock Rd Spartanburg SC
Free Cancellation
$68 nightly
The price is $75 total per night
$75 total
Jan 10 - Jan 11, 2026
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour business center. A computer station is provided and the front desk is staffed around-the-clock.
Breakfast included
Pet friendly
Four Points by Sheraton Spartanburg

Four Points by Sheraton Spartanburg

3 out of 5
9027 Fairforest Rd Spartanburg SC
Free Cancellation
Reserve now, pay when you stay
$101 nightly
The price is $112 total per night
$112 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the 24-hour gym and perks like free self parking.
Pool
Pet friendly
Holiday Inn Express Gaffney by IHG

Holiday Inn Express Gaffney by IHG

2.5 out of 5
1031 HYATT STREET Gaffney SC
Free Cancellation
$78 nightly
The price is $85 total per night
$85 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like full breakfast and free self parking.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in Mayo
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Cowpens Library

Cowpens Library is just one of the places to see in Cowpens, so why not enjoy the other things to explore during your travels?

Cowpens Library

Cowpens Veterans Memorial Park

Cowpens Veterans Memorial Park is just one of the places to see in Cowpens, so why not enjoy the other things to explore during your travels?

Cowpens Veterans Memorial Park

Cowpens Depot Museum and Civic Center

You can spend time studying the exhibits at Cowpens Depot Museum and Civic Center during your travels in Cowpens.

Cowpens Depot Museum and Civic Center

Frequently asked questions

How much are vacation packages to Mayo?
With a Travelocity vacation package, you can live it up in Mayo for as low as . Flights, hotels and experiences — we've got you. You'll save a bunch just by combining your bookings together. And with all that taken care of before leaving, you don't have to worry about a thing.
Where can I get the best vacation package deals for Mayo?
With at least 400 partner airlines and 1,000,000 properties all over the world, it's hard to top Travelocity. Take advantage of our comprehensive range and create the perfect package deal to Mayo. Don't you love it when travel is that easy?
Why should I purchase my Mayo vacation bundle via Travelocity?
From exciting destinations to one-of-a-kind experiences, we have everything you need to appease your wanderlust. Our 24/7 customer support will also make sure you're taken care of while you're on your getaway. And don't worry if you find a cheaper price on your reservation, we'll match it. That's our Price Match Guarantee.
Can I save money on my Mayo car rental if I book it with my hotel or flight?
Bundling your flight, hotel and car into a Mayo vacation package is an easy way to score an amazing deal. Plus, having your own wheels gives you freedom to get to all those big sights you'd like to explore. Located 110 mi from Mayo, Dollywood is one place that should be on your must-do list. Turn up the tunes and make a day trip of it.
Which airport is best for Mayo?
Charlotte-Douglas Intl. Airport (CLT) (55 mi away from downtown), Greenville-Spartanburg Intl. Airport (GSP) (25 mi away from central Mayo) and Asheville Regional Airport (AVL) (45 mi away from central Mayo) are the main hubs in Mayo.

Photos of local treasures

Browse Mayo vacation photos for more inspiration