Book Hotels in Matthews, MO
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Top Matthews hotels

Hampton Inn By Hilton Dexter
2179 Gill Plaza Drive Dexter MO
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $127 total per night from Jul 10 to Jul 11
$127 total
Jul 10 - Jul 11
Total with taxes and fees
A gym is on site and the staff is available around-the-clock at the 24-hour front desk.
"Breakfast was nice and the staff working the meal was attentive."
Reviewed on Jun 29, 2026

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $128 total per night from Jul 6 to Jul 7
$128 total
Jul 6 - Jul 7
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"This property is well maintained,very clean, comfy and full of friendly staff!"
Reviewed on Jun 30, 2026

Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $124 total per night from Jul 26 to Jul 27
$124 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink at the ...
"It was absolutely wonderful! The staff was helpful, and I loved how clean everything was!"
Reviewed on Jun 24, 2026

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $115 total per night from Jul 12 to Jul 13
$115 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. ...
"Great location! Friendly and accommodating staff!"
Reviewed on Jun 28, 2026

Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr Sikeston MO
Fully refundable
$107 nightly
The price is $121 total per night from Jul 26 to Jul 27
$121 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"They started breakfast an 1/2 hr before the regular scheduled time as there were a lot of people staying there for a biking event in East Prairie this weekend. That was nice! We did not have to get breakfast somewhere else. Clean facilities, friendly staff!"
Reviewed on Jun 28, 2026

Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $97 total per night from Jul 26 to Jul 27
$97 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...
"The room was clean. It is a little run down but not too bad at all. Be aware that you have to get a new key everyday. They didn't harass us over needing extra towels the first night but they ran out of towels the second night which is weird."
Reviewed on Jun 29, 2026

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane Sikeston MO
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $76 total per night from Jul 5 to Jul 6
$76 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
"Stay was good, clean room"
Reviewed on Jun 30, 2026

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $78 total per night from Jul 13 to Jul 14
$78 total
Jul 13 - Jul 14
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
"The air conditioning was good! But not very clean room. Hair everywhere. Strange fluids on bed and couch. Very spacious. You get what you pay for."
Reviewed on Jun 29, 2026

Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave Sikeston MO
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $72 total per night from Jul 26 to Jul 27
$72 total
Jul 26 - Jul 27
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like on-the-go breakfast and WiFi in ...
"The place smelled funny (cleaning supplies? Furniture was old and dirty Meeger breakfast choices Staff was helpful. Check-in was very good"
Reviewed on Jun 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Matthews hotel reviews by fellow wanderers

Drury Inn & Suites Sikeston, MO
5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"This property is well maintained,very clean, comfy and full of friendly staff!"
A verified traveler stayed at Drury Inn & Suites Sikeston, MO






