Book Hotels in Matthews, MO
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Top Matthews hotels

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $108 total per night from Nov 15 to Nov 16
$108 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Truly wonderful hotel! Desk staff lady at check in was so funny and welcoming to our 4 year old grandson! He absolutely LOVED the wonderful pool"
Reviewed on Nov 11, 2026

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $76 total per night from Nov 15 to Nov 16
$76 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $115 total per night from Nov 19 to Nov 20
$115 total
Nov 19 - Nov 20
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. ...

Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $83 total per night from Dec 7 to Dec 8
$83 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...

Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave Sikeston MO
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $66 total per night from Nov 18 to Nov 19
$66 total
Nov 18 - Nov 19
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like on-the-go breakfast and WiFi in ...

Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr Sikeston MO
Fully refundable
$101 nightly
The price is $115 total per night from Nov 15 to Nov 16
$115 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...

Hampton Inn By Hilton Dexter
2179 Gill Plaza Drive Dexter MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $111 total per night from Nov 22 to Nov 23
$111 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Relax with a drink at the bar/lounge and enjoy perks like free self parking and free WiFi. A 24-hour business ...

Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $125 total per night from Nov 19 to Nov 20
$125 total
Nov 19 - Nov 20
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink at the ...

The Riverstone Hotel Charleston-Sikeston
102 Drake St Charleston MO
Fully refundable
$66 nightly
The price is $74 total per night from Nov 14 to Nov 15
$74 total
Nov 14 - Nov 15
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 24-hour ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Matthews hotel reviews by fellow wanderers

Drury Inn & Suites Sikeston, MO
5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Truly wonderful hotel! Desk staff lady at check in was so funny and welcoming to our 4 year old grandson! He absolutely LOVED the wonderful pool"
A verified traveler stayed at Drury Inn & Suites Sikeston, MO



