Book Hotels in Matthews, MO

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Top Matthews hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $110 total per night from Nov 19 to Nov 20
$110 total
Nov 19 - Nov 20
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
The room was very clean. The front desk staff were courteous and helpful.

Reviewed on Nov 9, 2025

Opens in a new windowDrury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $89 total per night from Nov 30 to Dec 1
$89 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Everything was clean, staff was friendly

Reviewed on Nov 9, 2025

Opens in a new windowPear Tree Inn Sikeston
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

2.5 out of 5
1239 Commerce Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Nov 21 to Nov 22
$114 total
Nov 21 - Nov 22
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate ...
No doubt you will enjoy

Reviewed on Oct 17, 2025

Opens in a new windowFairfield Inn & Suites by Marriott Sikeston
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $108 total per night from Nov 21 to Nov 22
$108 total
Nov 21 - Nov 22
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. ...
Room was great pool was great. Breakfast was ok no cold cereal and waffles seemed to be only chocolate said vanilla with malt but looked and tasted chocolate and the other batter said chocolate. I prefer plain or cereal. hot chocolate bar was great we really liked that.

Reviewed on Nov 9, 2025

Opens in a new windowHampton Inn Sikeston
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 out of 5
100 Matthews Lane, Sikeston, MO
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $68 total per night from Nov 16 to Nov 17
$68 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
Courteous staff. Clean, and a large room.

Reviewed on Oct 28, 2025

Opens in a new windowTravel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $96 total per night from Nov 23 to Nov 24
$96 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...
Friendly staff, super clean, great breakfast. What else can you ask for at this price point?

Reviewed on Nov 12, 2025

Opens in a new windowBest Western Plus Sikeston
New Orleans Inn Portageville

New Orleans Inn Portageville

2.5 out of 5
600 US-61, Portageville, MO
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $68 total per night from Nov 16 to Nov 17
$68 total
Nov 16 - Nov 17
Total with taxes and fees
Free self parking is available and the motel's front desk is staffed around-the-clock. A garden is also provided.
Ok, just a little rundown.

Reviewed on Nov 9, 2025

Opens in a new windowNew Orleans Inn Portageville
Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter

2 out of 5
1608 E Business US 60, Dexter, MO
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $98 total per night from Nov 16 to Nov 17
$98 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the business center. A restaurant, ...
Sweet

Reviewed on Oct 17, 2025

Opens in a new windowTravelodge by Wyndham Dexter
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $72 total per night from Nov 18 to Nov 19
$72 total
Nov 18 - Nov 19
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
Large property, great for dogs.

Reviewed on Nov 7, 2025

Opens in a new windowDays Inn and Suites by Wyndham Sikeston
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Matthews?
Family vacations are where wonderful memories are made, but it's no secret that traveling with children can be a challenge. These kid-friendly Matthews hotels come with perks that aim to keep guests of all ages comfortable and happy: Unpack your bags at Hampton Inn Sikeston. It comes with complimentary breakfast, a swimming pool and a flair for making families feel welcome. Also consider Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel. It offers complimentary breakfast, a swimming pool and ample opportunities for precious family time.
Where can I find cheap hotels in Matthews?
At Travelocity you'll find really nice hotels in Matthews at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Matthews rather than in Matthews. We may find you even better rates, too.
How do I find the best Matthews hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Matthews then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Matthews?
The cheapest hotel in Matthews is $68. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Matthews?
There are 39 hotels in Matthews on Travelocity.
What are the best hotels in Matthews?
Matthews has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Matthews for you!
When is the best time to visit Matthews?
If you want the joy of a fun-filled trip in peak season, visit Matthews during June, August and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, September and November.
When is the cheapest time to stay in Matthews?
Based on historic data is usually the cheapest month to visit Matthews. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Matthews?
There are multiple hotels in Matthews that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Matthews. We have plenty of kid-friendly hotels in Matthews to choose from on Travelocity!
Why book a hotel in Matthews through Travelocity?
Because we have the top hotels in Matthews! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Matthews on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Matthews hotel reviews by fellow wanderers

Best Western Plus Sikeston

Best Western Plus Sikeston

5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Friendly staff, super clean, great breakfast. What else can you ask for at this price point? "
A verified traveler stayed at Best Western Plus Sikeston
Best Western Plus Sikeston

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