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Top Matthews hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $128 total per night from Sep 20 to Sep 21
$128 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"I love this hotel it is my go to weekend getaway. So clean so comfortable always great food and the bartender is friendly and funny I have followed her from the pear tree next door. Their pool is good for rain or shine"

Reviewed on Sep 15, 2026

Opens in a new windowDrury Inn & Suites Sikeston, MO
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

2.5 out of 5
2179 Gill Plaza Drive Dexter MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $110 total per night from Sep 27 to Sep 28
$110 total
Sep 27 - Sep 28
Total with taxes and fees
A gym is on site and the staff is available around-the-clock at the 24-hour front desk.
"Very nice hotel - our favorite when we visit the grandkids! Our only issue this time was with housekeeping. We arrived Friday afternoon, asked that our room be serviced on Sunday, (they only do it every other day), and it was not done. Also, in the shower were the usual shampoo and shower gel, but ..."

Reviewed on Sep 15, 2026

Opens in a new windowHampton Inn By Hilton Dexter
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $115 total per night from Oct 11 to Oct 12
$115 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. ...
"Really quiet place close to good restaurants and stores."

Reviewed on Sep 8, 2026

Opens in a new windowHampton Inn Sikeston
New Orleans Inn Portageville

New Orleans Inn Portageville

2.5 out of 5
600 US-61 Portageville MO
Free self parking is available and the motel's front desk is staffed around-the-clock. A garden is also provided.
"When I checked in, my key didn't work at all and had to be let in by staff, who was not there the rest of the night, so I was basically stuck in my room from 7pm to the time I left, which wasn't great. The room was relatively clean, the carpet seemed new. The room did feel humid and the bed was covered ..."

Reviewed on Aug 11, 2026

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Opens in a new windowNew Orleans Inn Portageville
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $76 total per night from Sep 17 to Sep 18
$76 total
Sep 17 - Sep 18
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
"The room did not have an extra roll of toilet paper and also the hairdryer did not work. That was the only two things that was not. I was not happy with."

Reviewed on Sep 13, 2026

Opens in a new windowDays Inn and Suites by Wyndham Sikeston
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $99 total per night from Sep 20 to Sep 21
$99 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...
Opens in a new windowBest Western Plus Sikeston I-55
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2 out of 5
2609 E Malone Ave Sikeston MO
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $65 total per night from Sep 21 to Sep 22
$65 total
Sep 21 - Sep 22
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like on-the-go breakfast and WiFi in ...
Opens in a new windowSuper 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St Charleston MO
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $66 total per night from Sep 16 to Sep 17
$66 total
Sep 16 - Sep 17
Total with taxes and fees
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. There's a computer ...
Opens in a new windowSuper 8 by Wyndham Charleston/Sikeston East MO
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr Sikeston MO
Fully refundable
$105 nightly
The price is $119 total per night from Oct 11 to Oct 12
$119 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Opens in a new windowHoliday Inn Express & Suites Sikeston Southwest by IHG
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Matthews?
Family vacations are where wonderful memories are made, but it's no secret that traveling with children can be a challenge. These kid-friendly Matthews hotels come with perks that aim to keep guests of all ages comfortable and happy: Unpack your bags at Hampton Inn Sikeston. It comes with complimentary breakfast, a swimming pool and a flair for making families feel welcome. Also consider Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel. It offers complimentary breakfast, a swimming pool and ample opportunities for precious family time.
Where can I find cheap hotels in Matthews?
At Travelocity you'll find really nice hotels in Matthews at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Matthews rather than in Matthews. We may find you even better rates, too.
How do I find the best Matthews hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Matthews then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Matthews?
The cheapest hotel in Matthews is $65. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Matthews?
There are 43 hotels in Matthews on Travelocity.
What are the best hotels in Matthews?
Matthews has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Matthews for you!
When is the best time to visit Matthews?
If you want the joy of a fun-filled trip in peak season, visit Matthews during June, August and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, September and November.
When is the cheapest time to stay in Matthews?
Based on historic data is usually the cheapest month to visit Matthews. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Matthews?
There are multiple hotels in Matthews that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Matthews. We have plenty of kid-friendly hotels in Matthews to choose from on Travelocity!
Why book a hotel in Matthews through Travelocity?
Because we have the top hotels in Matthews! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Matthews on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Matthews hotel reviews by fellow wanderers

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"I love this hotel it is my go to weekend getaway. So clean so comfortable always great food and the bartender is friendly and funny I have followed her from the pear tree next door. Their pool is good for rain or shine"
A verified traveler stayed at Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO

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