Book Hotels in Matthews, MO
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Top Matthews hotels

Hampton Inn By Hilton Dexter
2179 Gill Plaza Drive Dexter MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $110 total per night from Apr 19 to Apr 20
$110 total
Apr 19 - Apr 20
Total with taxes and fees
Stay at this hotel in Dexter. Popular attractions The Heritage House and Keller Veteran Memorial are located nearby.
Hotel is brand new. Walmart is close by and there are a lot of restaurants to choose from for a small town.
Reviewed on Apr 5, 2026

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $122 total per night from Apr 12 to Apr 13
$122 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Clean, friendly staff, comfortable!
Reviewed on Apr 6, 2026

Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $125 total per night from Apr 16 to Apr 17
$125 total
Apr 16 - Apr 17
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate ...
Quick and friendly check where they offered us bottles of water. They added a lounge/bar that is very convenient. The outside lounge are is very nice as well. Room is clean with a comfortable bed and 2 different styles of pillows. Which is nice considering most hotels give you one kind of pillow ...
Reviewed on Apr 3, 2026

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $115 total per night from May 3 to May 4
$115 total
May 3 - May 4
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. ...
Was very clean & pet-friendly. Great place to stop on toad
Reviewed on Apr 4, 2026

Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Apr 12 to Apr 13
$87 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...
The bed and chair was hard. Will not go back
Reviewed on Mar 30, 2026

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane Sikeston MO
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $69 total per night from Apr 23 to Apr 24
$69 total
Apr 23 - Apr 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
Yes
Reviewed on Apr 3, 2026

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $78 total per night from Apr 12 to Apr 13
$78 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
Very clean and friendly service
Reviewed on Apr 6, 2026

Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave Sikeston MO
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $71 total per night from Apr 12 to Apr 13
$71 total
Apr 12 - Apr 13
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like on-the-go breakfast and WiFi in ...
Room was supposed to be non smoking room but smelled of smoke.
Reviewed on Mar 16, 2026

Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr Sikeston MO
Fully refundable
$93 nightly
The price is $105 total per night from Apr 12 to Apr 13
$105 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Matthews hotel reviews by fellow wanderers

Drury Inn & Suites Sikeston, MO
5 out of 5
Posted 11 hours ago
Travelocity Verified Review
"Clean, friendly staff, comfortable!"
A verified traveler stayed at Drury Inn & Suites Sikeston, MO






