Book Hotels in Matthews, MO

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Top Matthews hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $103 total per night from Feb 15 to Feb 16
$103 total
Feb 15 - Feb 16
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Great

Reviewed on Feb 4, 2026

Opens in a new windowDrury Inn & Suites Sikeston, MO
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

2.5 out of 5
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Feb 19 to Feb 20
$114 total
Feb 19 - Feb 20
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate ...
Clean rooms great staff

Reviewed on Feb 1, 2026

Opens in a new windowFairfield Inn & Suites by Marriott Sikeston
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $108 total per night from Feb 28 to Mar 1
$108 total
Feb 28 - Mar 1
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. ...
The desk clerk was very welcoming. The hotel was clean and our room was nice. Good breakfast selection. Would definitely stay here again if in the area.

Reviewed on Feb 7, 2026

Opens in a new windowHampton Inn Sikeston
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 out of 5
100 Matthews Lane Sikeston MO
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $67 total per night from Feb 10 to Feb 11
$67 total
Feb 10 - Feb 11
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
Room was clean. Fairly quiet room. Front desk was kind. Would stay here again. .

Reviewed on Jan 30, 2026

Opens in a new windowTravel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $97 total per night from Feb 22 to Feb 23
$97 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...
Great breakfast. Clean room Quiet

Reviewed on Jan 31, 2026

Opens in a new windowBest Western Plus Sikeston
New Orleans Inn Portageville

New Orleans Inn Portageville

2.5 out of 5
600 US-61 Portageville MO
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $65 total per night from Feb 15 to Feb 16
$65 total
Feb 15 - Feb 16
Total with taxes and fees
Free self parking is available and the motel's front desk is staffed around-the-clock. A garden is also provided.
Fairly clean.

Reviewed on Feb 2, 2026

Opens in a new windowNew Orleans Inn Portageville
Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter

2 out of 5
1608 E Business US 60 Dexter MO
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $98 total per night from Feb 16 to Feb 17
$98 total
Feb 16 - Feb 17
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the business center. A restaurant, ...
Everything is nice accept the Direct tv never works and their internet is terrible. Other than those 2 things it has been pleasant staying here. The manager corrected the problem with our checking in and the staff not knowing what to do. The cleaning staff is very nice and accommodating. The room ...

Reviewed on Jan 10, 2026

Opens in a new windowTravelodge by Wyndham Dexter
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $78 total per night from Feb 11 to Feb 12
$78 total
Feb 11 - Feb 12
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
Clean comfy stay ! Thanks

Reviewed on Feb 2, 2026

Opens in a new windowDays Inn and Suites by Wyndham Sikeston
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2 out of 5
2609 E Malone Ave Sikeston MO
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $68 total per night from Feb 10 to Feb 11
$68 total
Feb 10 - Feb 11
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like on-the-go breakfast and WiFi in ...
Greatness

Reviewed on Feb 3, 2026

Opens in a new windowSuper 8 by Wyndham Sikeston/Miner Area
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Matthews?
Family vacations are where wonderful memories are made, but it's no secret that traveling with children can be a challenge. These kid-friendly Matthews hotels come with perks that aim to keep guests of all ages comfortable and happy: Unpack your bags at Hampton Inn Sikeston. It comes with complimentary breakfast, a swimming pool and a flair for making families feel welcome. Also consider Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel. It offers complimentary breakfast, a swimming pool and ample opportunities for precious family time.
Where can I find cheap hotels in Matthews?
At Travelocity you'll find really nice hotels in Matthews at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Matthews rather than in Matthews. We may find you even better rates, too.
How do I find the best Matthews hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Matthews then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Matthews?
The cheapest hotel in Matthews is $65. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Matthews?
There are 38 hotels in Matthews on Travelocity.
What are the best hotels in Matthews?
Matthews has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Matthews for you!
When is the best time to visit Matthews?
If you want the joy of a fun-filled trip in peak season, visit Matthews during June, August and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, September and November.
When is the cheapest time to stay in Matthews?
Based on historic data is usually the cheapest month to visit Matthews. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Matthews?
There are multiple hotels in Matthews that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Matthews. We have plenty of kid-friendly hotels in Matthews to choose from on Travelocity!
Why book a hotel in Matthews through Travelocity?
Because we have the top hotels in Matthews! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Matthews on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Matthews hotel reviews by fellow wanderers

Hampton Inn Sikeston

Hampton Inn Sikeston

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"The desk clerk was very welcoming. The hotel was clean and our room was nice. Good breakfast selection. Would definitely stay here again if in the area."
A verified traveler stayed at Hampton Inn Sikeston
Hampton Inn Sikeston

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