Book Hotels in Matthews, MO
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Matthews hotels

Hampton Inn By Hilton Dexter
2179 Gill Plaza Drive Dexter MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $110 total per night from Apr 12 to Apr 13
$110 total
Apr 12 - Apr 13
Total with taxes and fees
Stay at this hotel in Dexter. Popular attractions The Heritage House and Keller Veteran Memorial are located nearby.
Great place, nice and clean
Reviewed on Mar 27, 2026

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $108 total per night from Apr 9 to Apr 10
$108 total
Apr 9 - Apr 10
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
We decided we will stay here next year on our trip home from Texas.
Reviewed on Apr 3, 2026

Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $125 total per night from Apr 12 to Apr 13
$125 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate ...
Quick and friendly check where they offered us bottles of water. They added a lounge/bar that is very convenient. The outside lounge are is very nice as well. Room is clean with a comfortable bed and 2 different styles of pillows. Which is nice considering most hotels give you one kind of pillow ...
Reviewed on Apr 3, 2026

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $108 total per night from Apr 12 to Apr 13
$108 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. ...
Yes, breakfast was fresh. Room temperature was comfortable. Overall stay was good. Would stay there again
Reviewed on Mar 31, 2026

Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $89 total per night from Apr 5 to Apr 6
$89 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...
The bed and chair was hard. Will not go back
Reviewed on Mar 30, 2026

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane Sikeston MO
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $69 total per night from Apr 5 to Apr 6
$69 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
Yes
Reviewed on Apr 3, 2026

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $73 total per night from Apr 5 to Apr 6
$73 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
The floor in the room was dirty. It needed sweeping. There was a large ball of human hair on the floor near the bed. The bed spread had 2 red stains on the cover. The sink in the bathroom had a defective stopper. The cover control rod was not working. To flush the toilet, you had to continuously ...
Reviewed on Mar 30, 2026

Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave Sikeston MO
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $68 total per night from Apr 5 to Apr 6
$68 total
Apr 5 - Apr 6
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like on-the-go breakfast and WiFi in ...
Room was supposed to be non smoking room but smelled of smoke.
Reviewed on Mar 16, 2026

Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr Sikeston MO
Fully refundable
$96 nightly
The price is $109 total per night from Apr 12 to Apr 13
$109 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Matthews hotel reviews by fellow wanderers

Fairfield Inn & Suites by Marriott Sikeston
5 out of 5
Posted 6 hours ago
Travelocity Verified Review
"Quick and friendly check where they offered us bottles of water. They added a lounge/bar that is very convenient. The outside lounge are is very nice as well. Room is clean with a comfortable bed and 2 different styles of pillows. Which is nice considering most hotels give you one kind of pillow and it is not great. "
A verified traveler stayed at Fairfield Inn & Suites by Marriott Sikeston






