Book Hotels in Matthews, MO
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Top Matthews hotels
Fairfield by Marriott Inn & Suites Sikeston
1239 Commerce Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $138 total per night from Jul 20 to Jul 21
$138 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate ...
"Nice hotel"
Reviewed on Jul 10, 2025

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $117 total per night from Jul 20 to Jul 21
$117 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"The staff here from check in to the morning breakfast were welcoming and friendly. Cost was reasonable. I loved seeing the dogs and that it is pet friendly. Everything was clean. The location was close to places to eat - we even walked to El Bracero for dinner. I would highly recommend"
Reviewed on Jul 11, 2025

Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $103 total per night from Jul 13 to Jul 14
$103 total
Jul 13 - Jul 14
Total includes taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Excellent place to stay. Good breakfast choices. Good pool and hot tub."
Reviewed on Jul 9, 2025

Hampton Inn Sikeston
1240 Commerce Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $134 total per night from Jul 18 to Jul 19
$134 total
Jul 18 - Jul 19
Total includes taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. ...
"Not bad"
Reviewed on Jul 6, 2025

Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $100 total per night from Aug 10 to Aug 11
$100 total
Aug 10 - Aug 11
Total includes taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...
"We were travelling through and were pleasantly surprised at how well maintained the hotel was. Also breakfast was great with eggs and biscuits and gravy. Would definitely stay again."
Reviewed on Jul 8, 2025

Comfort Inn & Suites Sikeston I-55
109 Matthews Ln, Sikeston, MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $102 total per night from Aug 10 to Aug 11
$102 total
Aug 10 - Aug 11
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self parking and ...
"It was cool"
Reviewed on Jun 24, 2025

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $92 total per night from Jul 14 to Jul 15
$92 total
Jul 14 - Jul 15
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
Keep up the renovations
"This hotel looked like an old apartment building renovation into a hotel with much wrk in progress. Decent stay. Spacious. Very minimal breakfast offerings. The geese outside sure left messes everywhere but the greeting cat was a nice touch"
Reviewed on Jun 28, 2025

Dexter Inn
1807 W Business US Highway 60, Dexter, MO
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $77 total per night from Jul 13 to Jul 14
$77 total
Jul 13 - Jul 14
Total includes taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk ...
"I always stay here when I’m in town. Great place"
Reviewed on Jun 19, 2025

Super 8 by Wyndham Charleston/Sikeston East MO
310 S Story St, Charleston, MO
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $72 total per night from Jul 13 to Jul 14
$72 total
Jul 13 - Jul 14
Total includes taxes and fees
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. There's a computer ...
"A great surprise in Owasso! Great price and excellent room. So impressed."
Reviewed on Jul 6, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Matthews hotel reviews by fellow wanderers

Drury Inn & Suites Sikeston, MO
5 out of 5
Posted 20 hours ago
Travelocity Verified Review
"The staff here from check in to the morning breakfast were welcoming and friendly. Cost was reasonable. I loved seeing the dogs and that it is pet friendly. Everything was clean. The location was close to places to eat - we even walked to El Bracero for dinner. I would highly recommend "
A verified traveler from Rolling Prairie stayed at Drury Inn & Suites Sikeston, MO
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An Attraction
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