Deals on vacations and trips to Guadalupe

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Guadalupe flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $915, price is now $673 per person
$673
per person
Mar 14 - Mar 18
found 1 day ago
Roundtrip non-stop flight included
Charlotte (CLT) to Panama City (PTY)
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,485, price is now $964 per person
$964
per person
Mar 14 - Mar 18
found 1 day ago
Roundtrip non-stop flight included
Charlotte (CLT) to Panama City (PTY)
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.
MARINN PLACE Financial District

MARINN PLACE Financial District

3.5 out of 5
Bella Vista
Price was $1,106, price is now $749 per person
$749
per person
Mar 14 - Mar 18
found 1 day ago
Roundtrip non-stop flight included
Charlotte (CLT) to Panama City (PTY)
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $1,286, price is now $938 per person
$938
per person
Mar 14 - Mar 18
found 1 day ago
Roundtrip non-stop flight included
Charlotte (CLT) to Panama City (PTY)
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.
Playa Caracol Residences Vacation Rental

Playa Caracol Residences Vacation Rental

3.5 out of 5
Price was $1,250, price is now $917 per person
$917
per person
Feb 13 - Feb 18
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
This smoke-free apartment features 2 outdoor pools, a restaurant, and a bar/lounge. Relax with a drink at the poolside bar and enjoy perks like free self parking. A coffee shop and a snack bar/deli are also provided.

Top Guadalupe hotels deals

Backpackers Las Pesas

Backpackers Las Pesas

2 out of 5
La Chorrera, vía interamericana, Panama City Panama
Get rates
Stay at this hotel in La Chorrera.
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$142 nightly
The price is $156 total per night
$156 total
Dec 20 - Dec 21
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the a rooftop terrace and visit the 2 bars/lounges and poolside bar for drinks.
Pool
Pet friendly
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5 out of 5
Km 6 Road to Veracruz Veracruz Panama
Free Cancellation
Reserve now, pay when you stay
$228 nightly
The price is $251 total per night
$251 total
Jan 8 - Jan 9, 2026
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and 4 restaurants. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. There's fun for all ages with a free kid's club and a children's pool, and families will appreciate the onsite laundry facilities.
On private beach
Pool
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
$401 nightly
The price is $401 total per night
$401 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
A full-service spa, a nightclub, and 4 outdoor pools are all featured at this all-inclusive property. Spend a day at the beach kayaking, or relax with free beach cabanas and sun loungers. There's fun for all ages with a free kid's club and mini golf, and in-room childcare is an added bonus.
Pool
Breakfast included
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

4.5 out of 5
Amador Avenue & Van Hook Street Panama City Panama
Free Cancellation
$82 nightly
The price is $91 total per night
$91 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 2 outdoor pools, and a gym. Families will appreciate the children's pool and onsite laundry facilities. Unwind with a drink at the bar/lounge and enjoy perks like free self parking and a free shopping center shuttle.
Pool
Parking included
Summit Rainforest & Golf Resort

Summit Rainforest & Golf Resort

4 out of 5
Omar Torrijos Ave Panama City Panama
Free Cancellation
Reserve now, pay when you stay
$71 nightly
The price is $79 total per night
$79 total
Dec 28 - Dec 29
Total with taxes and fees
A golf course, 3 restaurants, and 2 outdoor pools are all featured at this hotel. Bring the family and enjoy the children's pool, playground, and kid-friendly dining. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like continental breakfast and free self parking.
Pool
Breakfast included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much are vacation packages to Guadalupe?
You might be surprised — you can unwind in Guadalupe for as little as $673. Let Travelocity save you money and hassle with our fantastic vacation packages. With experiences, hotels and flights all ready to be snapped up, what's holding you back?
Where can I get the best vacation package deals for Guadalupe?
With at least 400 air carriers and 1,000,000 properties all over the world, you can't beat Travelocity. Scroll through our comprehensive range and grab an affordable package deal to Guadalupe. Don't you love it when travel is that easy?
Why should I purchase my Guadalupe vacation package via Travelocity?
Because life is all about the journey, and we have all you need to help you on your way. With our top-quality service and Price Match Guarantee, you can book your trip with confidence. What's more, you can sleep easy while you're on the road knowing we're always available to chat via our 24/7 customer support.
Can I save money on my Guadalupe car rental if I combine it with a hotel or flight?
Combining your bookings into a Guadalupe vacation package will save you some serious money. You can choose a flight and car; a hotel, flight and car; or a car and hotel. You won't find a better way to discover the greater Guadalupe region than from behind the wheel of your own rental car. You can also add experiences and tours to your Travelocity package.
Which airport is best for Guadalupe?
One of your best options is Tocumen Intl. Airport (PTY), located 30 mi northeast of downtown Guadalupe. Another choice is Marcos A. Gelabert Intl. Airport (PAC), 19 mi away from central Guadalupe).

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