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Top Great River Road hotels
Les Carillons - Arts District Gem Large Groups Welcome! Pool! Elevator!
New Orleans LA
An outdoor pool is featured at this vacation home, along with laundry facilities.
"Great location. Would love to book again."
Reviewed on May 28, 2026
Reel Paradise at Shore Slough
Lansing IA
This cabin features a garden, laundry facilities, and barbecue grills.
"Great location and property !"
Reviewed on Jun 29, 2026
Nature Cabin | Cuyuna Matata
Mission Township MN
This vacation home features a hot tub and a sauna. Laundry facilities are provided for your convenience.
"We had the best time celebrating our 10 year anniversary. The property is beautiful and secluded. We love the view of the river. There’s so much to do in the area but we enjoyed relaxing at the Nature Cabin. Can’t beat a dip in the hot tub on a cool night! Katherine was responsive and gave us clear ..."
Reviewed on Jul 13, 2025
Fairfield Inn & Suites by Marriott La Crosse Downtown
434 Third Street South La Crosse WI
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $116 total per night from Jul 26 to Jul 27
$116 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Very nice hotel. Clean, modern, comfortable, and spacious. Continental breakfast was very good."
Reviewed on Jul 15, 2026
AmericInn by Wyndham Prairie du Chien
37502 Us Highway 35 And 18 S Prairie Du Chien WI
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $89 total per night from Jul 19 to Jul 20
$89 total
Jul 19 - Jul 20
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Clean, friendly, and great parking"
Reviewed on Jul 10, 2026
Days Inn by Wyndham Lake Village
912 Hwy 65/82 South Lake Village AR
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $82 total per night from Jul 19 to Jul 20
$82 total
Jul 19 - Jul 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
"Worst part was the very limited continental breakfast, a few granola bars, muffins, and yogurt, no juice, bad coffee. Room was just ok."
Reviewed on Jul 13, 2026
Tiny Pine A\ Cuyuna Matata
Mission Township MN
This vacation home features a hot tub and a sauna. Laundry facilities are provided for your convenience.
Guesthouse on Mississippi River Estate
Nauvoo IL
Stay at this vacation home in Nauvoo. Enjoy air conditioning. Popular attractions Nauvoo Public Library and Weld House Museum are located nearby.
Riverside Retreat: Unwind in a Cabin with Private Steam Sauna on the Pine River
Mission Township MN
A sauna is featured at this cabin, along with barbecue grills.
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Great River Road with star-rating
Check Great River Road Hotels by Star Rating
5 Star Hotels
11 properties
Recent Great River Road hotel reviews by fellow wanderers
Fairfield Inn & Suites by Marriott La Crosse Downtown
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Very nice hotel. Clean, modern, comfortable, and spacious. Continental breakfast was very good."
A verified traveler stayed at Fairfield Inn & Suites by Marriott La Crosse Downtown
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