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Top Great River Road hotels
Les Carillons - Arts District Gem Large Groups Welcome! Pool! Elevator!
New Orleans LA
An outdoor pool is featured at this vacation home, along with laundry facilities.
"Great location. Would love to book again."
Reviewed on May 28, 2026
Reel Paradise at Shore Slough
Lansing IA
This cabin features a garden, laundry facilities, and barbecue grills.
"This house was immaculate! Everything was exactly as listed. The house,pier, yard,deck, and screened in porch were picture perfect. We enjoyed relaxing on the decks watching the slow trains go by, and in the evening using the large firepit. We brought our boat that we were able to dock at the pier ..."
Reviewed on Jul 15, 2026
Nature Cabin | Cuyuna Matata
Mission Township MN
This vacation home features a hot tub and a sauna. Laundry facilities are provided for your convenience.
"We had the best time celebrating our 10 year anniversary. The property is beautiful and secluded. We love the view of the river. There’s so much to do in the area but we enjoyed relaxing at the Nature Cabin. Can’t beat a dip in the hot tub on a cool night! Katherine was responsive and gave us clear ..."
Reviewed on Jul 13, 2025
Fairfield Inn & Suites by Marriott La Crosse Downtown
434 Third Street South La Crosse WI
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $123 total per night from Aug 23 to Aug 24
$123 total
Aug 23 - Aug 24
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"When arriving in our room, it looked like the sheets weren’t changed ••kind of frumpy at the bottom edge of the bed. Breakfast was very nice.!"
Reviewed on Aug 4, 2026
AmericInn by Wyndham Prairie du Chien
37502 Us Highway 35 And 18 S Prairie Du Chien WI
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $84 total per night from Aug 16 to Aug 17
$84 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Days Inn by Wyndham Lake Village
912 Hwy 65/82 South Lake Village AR
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $83 total per night from Sep 6 to Sep 7
$83 total
Sep 6 - Sep 7
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
Tiny Pine A\ Cuyuna Matata
Mission Township MN
This vacation home features a hot tub and a sauna. Laundry facilities are provided for your convenience.
Guesthouse on Mississippi River Estate
Nauvoo IL
Stay at this vacation home in Nauvoo. Enjoy air conditioning. Popular attractions Nauvoo Public Library and Weld House Museum are located nearby.
Riverside Retreat: Unwind in a Cabin with Private Steam Sauna on the Pine River
Mission Township MN
A sauna is featured at this cabin, along with barbecue grills.
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Great River Road with star-rating
Check Great River Road Hotels by Star Rating
5 Star Hotels
11 properties
Recent Great River Road hotel reviews by fellow wanderers
Reel Paradise at Shore Slough
5 out of 5
Posted 3 weeks ago
Travelocity Verified Review
"This house was immaculate! Everything was exactly as listed. The house,pier, yard,deck, and screened in porch were picture perfect. We enjoyed relaxing on the decks watching the slow trains go by, and in the evening using the large firepit. We brought our boat that we were able to dock at the pier to take to different little private beaches, and to the tiki bar just down the way. We loved everything about this place and area. We would stay here again!"
A verified traveler stayed at Reel Paradise at Shore Slough
Les Carillons - Arts District Gem Large Groups Welcome! Pool! Elevator!
5 out of 5
Posted 3 months ago
Travelocity Verified Review
"Great location. Would love to book again."
A verified traveler stayed at Les Carillons - Arts District Gem
Large Groups Welcome! Pool! Elevator!
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