Book Hotels in Great River Road

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Great River Road hotels

Les Carillons - Arts District Gem 
Large Groups Welcome!  Pool! Elevator!

Les Carillons - Arts District Gem Large Groups Welcome! Pool! Elevator!

New Orleans LA
A hot tub is featured at this vacation home, along with laundry facilities.
"Great location. Would love to book again."

Reviewed on May 28, 2026

Opens in a new windowLes Carillons - Arts District Gem Large Groups Welcome! Pool! Elevator!
Reel Paradise at Shore Slough

Reel Paradise at Shore Slough

Lansing IA
This cabin features a garden, laundry facilities, and barbecue grills.
"Great location and property !"

Reviewed on Jun 29, 2026

Opens in a new windowReel Paradise at Shore Slough
Nature Cabin | Cuyuna Matata

Nature Cabin | Cuyuna Matata

Mission Township MN
This vacation home features a hot tub and a sauna. Laundry facilities are provided for your convenience.
"We had the best time celebrating our 10 year anniversary. The property is beautiful and secluded. We love the view of the river. There’s so much to do in the area but we enjoyed relaxing at the Nature Cabin. Can’t beat a dip in the hot tub on a cool night! Katherine was responsive and gave us clear ..."

Reviewed on Jul 13, 2025

Opens in a new windowNature Cabin | Cuyuna Matata
River Chalet | Cuyuna Matata

River Chalet | Cuyuna Matata

Mission Township MN
A sauna is featured at this vacation home, along with laundry facilities.
"Beautiful place nestled in the woods by the river. Wonderful kitchen with everything you need. Comfortable beds. We loved the place"

Reviewed on Jun 12, 2025

Opens in a new windowRiver Chalet | Cuyuna Matata
Fairfield Inn & Suites by Marriott La Crosse Downtown

Fairfield Inn & Suites by Marriott La Crosse Downtown

3 out of 5
434 Third Street South La Crosse WI
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $116 total per night from Jul 26 to Jul 27
$116 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Room was nice. The breakfast was good. When we checked in there was a sign saying the pool was closed for maintenance. No mention of this when booking. My kids were bummed. Pillows were too soft and flat."

Reviewed on Jun 30, 2026

Opens in a new windowFairfield Inn & Suites by Marriott La Crosse Downtown
AmericInn by Wyndham Prairie du Chien

AmericInn by Wyndham Prairie du Chien

3 out of 5
37502 Us Highway 35 And 18 S Prairie Du Chien WI
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $84 total per night from Jul 12 to Jul 13
$84 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Clean room breakfast was good bed hard as a rock"

Reviewed on Jun 28, 2026

Opens in a new windowAmericInn by Wyndham Prairie du Chien
Days Inn by Wyndham Lake Village

Days Inn by Wyndham Lake Village

2 out of 5
912 Hwy 65/82 South Lake Village AR
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $85 total per night from Jul 19 to Jul 20
$85 total
Jul 19 - Jul 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
"The room had no refrigerator and no iron for your clothes. Breakfast was nothing like expected. Parking was good and safe. The cost to stay should not have been as much."

Reviewed on Jun 16, 2026

Opens in a new windowDays Inn by Wyndham Lake Village
Tiny Pine A\ Cuyuna Matata

Tiny Pine A\ Cuyuna Matata

Mission Township MN
This vacation home features a hot tub and a sauna. Laundry facilities are provided for your convenience.
Opens in a new windowTiny Pine A\ Cuyuna Matata
Guesthouse on Mississippi River Estate

Guesthouse on Mississippi River Estate

Nauvoo IL
Stay at this vacation home in Nauvoo. Enjoy air conditioning. Popular attractions Nauvoo Public Library and Weld House Museum are located nearby.
Opens in a new windowGuesthouse on Mississippi River Estate
Don't see what you're looking for?
See all available properties in Great River Road
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Great River Road hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity