See all properties

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Enjoy free breakfast at this spa Cape Girardeau hotel

Choose dates to view prices

Photo gallery for Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Exterior
Indoor pool, open 8 AM to 11 PM, sun loungers
Premium bedding, down comforters, pillowtop beds, in-room safe
Free breakfast
Exterior

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Spa
  • Pool
  • Gym
  • Laundry
  • Housekeeping

Explore the area

View in a map
3253 William Street, Cape Girardeau, MO, 63701
  • Saint Francis Medical Center
    ‪6 min walk‬
  • Southeast Missouri State University
    ‪6 min drive‬
  • Isle Casino Cape Girardeau
    ‪8 min drive‬
  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪7 min drive‬

Room options

View all photos for Suite, 1 King Bed

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 1 King Bed

9.6 out of 10
Exceptional
(32 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room, 1 Queen Bed

Premium bedding, down comforters, pillowtop beds, in-room safe

Standard Room, 1 Queen Bed

9.2 out of 10
Wonderful
(5 reviews)
  • 400 sq ft
  • Sleeps 2
  • 1 Queen Bed

View all photos for Suite, 2 Queen Beds, Accessible (Mobility)

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 2 Queen Beds, Accessible (Mobility)

9.4 out of 10
Exceptional
(14 reviews)
  • 400 sq ft
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 2 Queen Beds

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 2 Queen Beds

9.6 out of 10
Exceptional
(52 reviews)
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 1 King Bed, Accessible (Roll-In Shower)

9.6 out of 10
Exceptional
(5 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room

Premium bedding, down comforters, pillowtop beds, in-room safe

Standard Room

8.4 out of 10
Very good
(5 reviews)
  • 400 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Suite, 2 Queen Beds, Accessible (Roll-In Shower) | Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

8.0 out of 10
Very good
(5 reviews)
  • 400 sq ft
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible (Mobility)

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 1 King Bed, Accessible (Mobility)

10.0 out of 10
Exceptional
(2 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 Bedroom (Feature)

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 1 Bedroom (Feature)

10.0 out of 10
Exceptional
(1 review)
  • Sleeps 2
  • 1 Queen Bed

About the neighborhood

Cape Girardeau

Near the airport.A stay at this hotel places you within half a mile (1 km) of Saint Francis Medical Center and 3 miles (5 km) of Saint Francis Healthcare System. Southeast Missouri Hospital and Cape Splash Family Aquatic Center are also within 3 miles (5 km).

What's nearby

  • Saint Francis Medical Center - 6 min walk - 0.4 miles
  • Southeast Missouri State University - 6 min drive - 3.5 miles
  • Riverfront Bridge Park - 7 min drive - 4.0 miles
  • Show Me Center - 8 min drive - 4.1 miles
  • Isle Casino Cape Girardeau - 8 min drive - 4.3 miles

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 10 min drive

Restaurants

  • ‪Chick-fil-A - ‬7 min walk
  • ‪McDonald's - ‬10 min walk
  • ‪Rhodes - ‬20 min walk
  • ‪Chili's Grill & Bar - ‬4 min walk
  • ‪White Castle - ‬10 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Enjoy free breakfast at this spa Cape Girardeau hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers its guests a full-service spa, an indoor pool, and a fitness center. Public spaces have free WiFi and wired Internet. A business center and a meeting room are available. Free breakfast is served. Event space at this hotel measures 118 square feet (11 square meters) and includes conference space. The business-friendly Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG also features a vending machine, complimentary newspapers in the lobby, and laundry facilities. Self parking is free.

This Cape Girardeau hotel is smoke free.

  • 1 building
  • 102 guestrooms or units
  • 4 levels
  • 118 sq ft of conference space
  • 11 sq m of conference space
  • Breakfast available (free)
  • Poolside lounge chairs
  • Business facilities
  • Conference space
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Storage area for luggage
  • Front-desk safe
  • Newspapers in lobby (free)
  • Bellhop
  • No smoking on site
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers 102 accommodations with safes and coffee/tea makers. Accommodations offer separate sitting areas. Pillowtop beds feature down comforters and premium bedding. A pillow menu is available. 52-inch flat-screen televisions come with premium cable channels. Bathrooms include complimentary toiletries and hair dryers.

Guests can surf the web using the complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Housekeeping is provided daily.

Guests can indulge in a pampering treatment at the hotel's full-service spa.

Similar properties

Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

  • Pool
  • Hot Tub
  • Breakfast included
  • Pet friendly
4.8 out of 5, Exceptional, 1,001 reviews
$90 nightly
The price is $102
Sep 7 - Sep 8
Total with taxes and fees
Drury Plaza Hotel Cape Girardeau Conference Center

Property amenities

Family friendly

  • In-room microwave
  • Indoor pool
  • Laundry facilities
  • Mini-fridge

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking available

Food and drink

  • Free breakfast available

Things to do

  • Full-service spa
  • Gym
  • Indoor pool

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator

Room amenities

Entertainment

  • 52-inch flat-screen TV with premium cable channels

Bedroom

  • Down comforter
  • Pillow menu
  • Pillowtop mattress
  • Premium bedding

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Food and drink

  • Coffee/tea maker
  • Microwave
  • Mini-fridge

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • No pets allowed

Children and extra beds

  • Children are welcome.
  • Cribs (infant beds) are not available.

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, JCB International, and Carte Blanche. Cash is not accepted. For guests' safety, the property includes a smoke detector in each accommodation. Cashless payment methods are available for all transactions. This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

We should mention

  • Pool access available from 8 AM to 11 PM.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Cape Girardeau I-55
Holiday Inn Express Hotel Cape Girardeau I-55
Holiday Inn Hotel I-55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Inn Express Cape Girarau I55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Frequently asked questions

How close is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG to the airport?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is 6.1 mi (10-min drive) away from the Cape Girardeau, MO (CGI-Cape Girardeau Municipal) airport, the closest popular airport to the property.

How much does it cost to stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

As of Sep 3, 2025, prices found for a 1-night stay for 2 adults at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG on Sep 14, 2025 start from $103.0, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have an airport shuttle?

Airport shuttle services are not available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offer free breakfast?

Yes, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers free breakfast.

Is there a casino at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

No, there is no casino at this hotel, but Isle Casino Cape Girardeau (7-min drive) is nearby.

What time is check-in at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Check-in start time: 3:00 PM; Check-in end time: anytime.

Is there free parking at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

This hotel offers free self parking.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a pool?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG features an indoor pool. Guests can enjoy pool access from 8 AM to 11 PM.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a spa?

Yes, this hotel has a spa.

How close is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG to downtown Cape Girardeau?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is 3.2 mi away from Cape Girardeau.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 784 out of 1000 reviews
Rating 8 - Good. 149 out of 1000 reviews
Rating 6 - Okay. 36 out of 1000 reviews
Rating 4 - Poor. 15 out of 1000 reviews
Rating 2 - Terrible. 16 out of 1000 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.2/10

Amenities

9.6/10

Property conditions & facilities

9.4/10

Eco-friendliness

Reviews

10/10 Excellent

francisco

Stayed 1 night in May 2025

10/10 Excellent

Frank

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff is phenomenal, and the room was very clean, accommodating all my needs.
Stayed 1 night in May 2025

4/10 Poor

Pat

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
Very noisy from the interstate and other people in the building
Stayed 1 night in May 2025

10/10 Excellent

Janita

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
I thought the property was very clean and appealing. Our check in clerk for our 1st night stay on May 22nd was very friendly, and helpful, however our 2nd stay on May 25th our clerk was unpleasant never said hello never smiled. She wasn't rude but she seemed very unfriendly and like she didn't want to be there. But our rooms were very clean, the breakfast was good, and the breakfast staff was very friendly as well. I would definitely stay here again in the future.
Stayed 1 night in May 2025

8/10 Good

Rebecca

Traveled with partner
Liked: Amenities
The beds were comfortable and the room was clean. The breakfast was cold and not very good.
Stayed 1 night in May 2025

10/10 Excellent

david

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent
Stayed 1 night in May 2025

8/10 Good

Terry

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice rooms. Loved the jacuzzi. Bed wasn't the most comfortable, but not a bad night's sleep. I'd stay again.
Stayed 1 night in May 2025

10/10 Excellent

Taylor

Traveled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice clean hotel. The beds were not hard as brick very comfortable.
Stayed 1 night in May 2025

10/10 Excellent

Julia

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Great location. Walmart close. Some rooms’ windows are facing the pool and this loud until 10pm if the pool is occupied. If you have anyone who goes to bed early stay away from those. Room are huge!!
Stayed 3 nights in May 2025

10/10 Excellent

JUAN

Traveled with family and small children
Liked: Amenities
Cleanliness and staff really helpful
Stayed 1 night in May 2025

10/10 Excellent

sylvian

Traveled with family and small children, Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Property is situated in a great spot! Lots to choose from for dining.
Stayed 2 nights in May 2025

10/10 Excellent

Tracy

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in May 2025

6/10 Okay

Scott

Business traveler, Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Personnel where polite and courteous
Stayed 1 night in Apr 2025

10/10 Excellent

Heidi

Liked: Cleanliness
Stayed 1 night in May 2025

8/10 Good

Carrie

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great room and good breakfast. Great place to stay with central location.
Stayed 1 night in May 2025

8/10 Good

Jacob

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Close to food and shopping not that far from SEMO
Stayed 2 nights in May 2025

10/10 Excellent

Gunnar

Stayed 2 nights in Apr 2025

8/10 Good

Dawn

Stayed 2 nights in Apr 2025

10/10 Excellent

Darci

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Apr 2025

8/10 Good

Jose

Stayed 1 night in Apr 2025

10/10 Excellent

Xenia

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Return Stay💋

I chose this hotel because I stayed 8 months ago when I daughter was scheduled for a C-section and I was so happy with the staff, location of the property and condition of the room I had to return.
Stayed 1 night in Apr 2025

10/10 Excellent

Nick

Traveled with group
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Front desk was super helpful at check in and very courteous throughout the whole stay
Stayed 2 nights in Apr 2025

10/10 Excellent

Lindsey

Traveled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Check-in was seamless. Staff was kind. They had fresh cookies at 8 p.m. which the kids loved. The pool area is very well maintained and nice. Fitness area looked very nice right through the pool area. Rooms are clean, decent and in good repair, and the hotel is quiet. Could not be happier with the value of this stay for my family. We have Panera, Starbucks, Chik-fil-a, Texas Roadhouse, Cracker Barrel and more right around our hotel. There is a shopping center nearby with a TJmaxx and some other stores. Overall a really great stop that we will remember when we take this route for future drives. Thank you, Holiday Inn Express!
Stayed 1 night in Apr 2025

10/10 Excellent

Theresa, Battle Creek

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Apr 2025

2/10 Terrible

William

Traveled with family
Liked: Room comfort
Disliked: Staff & service, property conditions & facilities

Bad place to stay

It was not a very good place for the money you pay the floor was squeaky upstairs so i heard that most of the night and also sounded like a heard of cattle running across the floor
Stayed 1 night in Apr 2025