Deals on vacations and trips to Eastern Panama

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Eastern Panama flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
Metro Hotel Panama

Metro Hotel Panama

3.5 out of 5
Bella Vista
Price was $873, price is now $595 per person
$595
per person
Jan 7 - Jan 14
found 4 hours ago
Roundtrip flight included
Port of Spain (POS) to Panama City (PTY)
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the business center and airport shuttle. You'll appreciate the shopping center shuttle, coffee shop/cafe, and computer station.
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Save 100% on your flight
Price was $2,743, price is now $1,280 per person
$1,280
per person
Dec 12 - Dec 17
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was $3,053, price is now $1,542 per person
$1,542
per person
Dec 5 - Dec 12
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet parking. Enjoy the 24-hour gym and unwind at the bar/lounge and poolside bar.
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Tocumen Airport
Price was $1,498, price is now $1,022 per person
$1,022
per person
Dec 12 - Dec 17
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
This smoke-free resort features a casino, 2 indoor tennis courts, and a restaurant. Bring the family and enjoy the children's pool, playground, and kid-friendly dining. Enjoy the outdoor pool and free perks like full breakfast and valet parking.
Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Bella Vista
Price was $1,797, price is now $1,274 per person
$1,274
per person
Dec 12 - Dec 17
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and airport shuttle. Relax with a drink at one of the 2 bars/lounges and enjoy perks like free valet parking.

Top Eastern Panama hotels deals

Ordovician Beach Resort

Ordovician Beach Resort

4.5 out of 5
Isla Grande Isla Grande Colon
$386 nightly
The price is $431 total per night
$431 total
Dec 2 - Dec 3
Total with taxes and fees
This smoke-free resort features a private beach, a full-service spa, and 2 restaurants. Relax with free beach cabanas, sun loungers, and beach umbrellas. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like full breakfast and free self parking.
Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island

2 out of 5
Diablo Island Narganá Guna Yala
$188 nightly
The price is $207 total per night
$207 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a restaurant, a garden, and a snack bar/deli. Enjoy the free local cuisine breakfast each morning.
san blas luxury tour

san blas luxury tour

2 out of 5
guna yala Nusatupo Guna Yala
$111 nightly
The price is $122 total per night
$122 total
Nov 6 - Nov 7
Total with taxes and fees
This cabin doesn't skimp on freebies - guests receive free full breakfast and a free beach shuttle. Relax with beach cabanas and beach umbrellas, and cool off with a drink at the beachside bar. You'll appreciate the area shuttle, beach bar, and a virtual front desk.
Ciel y Miel

Ciel y Miel

3 out of 5
Caillle Principale Cacique Provincia de Colón
$207 nightly
The price is $228 total per night
$228 total
Nov 2 - Nov 3
Total with taxes and fees
A full-service spa, 3 restaurants, and 4 outdoor pools are all featured at this smoke-free hotel. Relax with a drink at the beach bar and enjoy free perks like cooked-to-order breakfast and valet parking. A business center, free WiFi in public areas, and a terrace are also on offer.
Ranchos de Chalia

Ranchos de Chalia

3 out of 5
Portobelo via Puerto Lindo, Unit 3 Puerto Lindo Colón
$117 nightly
The price is $130 total per night
$130 total
Dec 2 - Dec 3
Total with taxes and fees
A restaurant and an outdoor pool are featured at this hotel. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. A garden and a virtual front desk are also provided.
Cocoloco - Catamaran Lagoon 52F SAN BLAS

Cocoloco - Catamaran Lagoon 52F SAN BLAS

3 out of 5
El Porvenir Narganá Guna Yala
Get rates
A restaurant and a bar/lounge are featured at this cruise ship. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A coffee shop and a snack bar/deli are also provided.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Eastern Panama attractions

Isla Diablo

Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area.
See properties

Frequently asked questions

How much are vacation packages to Eastern Panama?
Exciting adventures await in Eastern Panama, with Travelocity vacation packages starting from as low as $595. Including flights and hotels, these awesome deals make it a breeze to see more of our beautiful planet.
Where can I get the best vacation package deals for Eastern Panama?
You can snap up amazing Eastern Panama package deals with Travelocity. Mix and match from 400 air carriers and 1,000,000 worldwide properties and turn those travel dreams into a reality.
Why should I purchase my Eastern Panama vacation package with Travelocity?
We offer 24/7 support, top-quality service and a Price Match Guarantee. Life's a great big journey — and we have alluring destinations for you to journey to all across the world. Wander with us and your wallet will thank you for it.
Can I save money on my Eastern Panama car rental if I bundle it with my hotel or flight?
Certainly. And our Eastern Panama vacation packages are the perfect way to do it. In just a few clicks you can save cash as well as time by bundling your bookings. Pick up the keys to your rental car and feel the freedom of the open road. Searching for things to do? Add some tours or experiences to your package and make savings on those too.
What is there to do in Eastern Panama?
You'll be happy to know Eastern Panama is brimming with incredible things to see and do, however Isla Mamey and Cayos Holandeses are right up there with the very best.

Photos of local treasures

Browse Eastern Panama vacation photos for more inspiration

A calm sea with a small boat and a row of palm trees on the shore.
A man in a canoe with a sail on a turquoise sea, surrounded by palm trees.
A beach with waves, rocks, palm trees, and a boat.
A beach with palm trees and a boat on the water.
A beach with clear turquoise water, white sand, and palm trees.