Deals on vacations and trips to De Soto

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Price found within the past 48 hours. Click for updated prices.
Comfort Inn Onalaska - La Crosse Area

Comfort Inn Onalaska - La Crosse Area

2.5 out of 5
Price was $693, price is now $619 per person
$619
per person
Jan 22 - Jan 26
found 1 hour ago
Roundtrip non-stop flight included
Milwaukee (MKE) to La Crosse (LSE)
An indoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A terrace, a picnic area, and free newspapers are also on offer.
Gundersen Hotel & Suites

Gundersen Hotel & Suites

2.5 out of 5
Powell-Poage-Hamilton
Price was $822, price is now $673 per person
$673
per person
Jan 22 - Jan 26
found 1 hour ago
Roundtrip non-stop flight included
Milwaukee (MKE) to La Crosse (LSE)
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
The Charmant Hotel

The Charmant Hotel

4 out of 5
Historic Downtown La Crosse
Price was $1,107, price is now $962 per person
$962
per person
Jan 22 - Jan 26
found 1 hour ago
Roundtrip non-stop flight included
Milwaukee (MKE) to La Crosse (LSE)
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. A restaurant, a 24-hour front desk, and concierge services are also provided.
Holiday Inn Express & Suites Onalaska La Crosse Area by IHG

Holiday Inn Express & Suites Onalaska La Crosse Area by IHG

2.5 out of 5
Price was $739, price is now $652 per person
$652
per person
Jan 22 - Jan 26
found 1 hour ago
Roundtrip non-stop flight included
Milwaukee (MKE) to La Crosse (LSE)
This hotel features an indoor pool and a 24-hour gym. There's fun for all ages with a children's pool and an arcade/game room, and families will appreciate the onsite laundry facilities. Enjoy the hot tub and free perks like continental breakfast and free self parking.
Stoney Creek Hotel La Crosse - Onalaska

Stoney Creek Hotel La Crosse - Onalaska

2.5 out of 5
Price was $778, price is now $691 per person
$691
per person
Jan 22 - Jan 26
found 1 hour ago
Roundtrip non-stop flight included
Milwaukee (MKE) to La Crosse (LSE)
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference space. Enjoy the gym and free perks like continental breakfast and free self parking.

Top De Soto hotels deals

Cozy Ridge Retreat

Cozy Ridge Retreat

De Soto WI
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This cabin features laundry facilities.
Kitchen
Washer
Romantic Log Cabin Hideaway, Hot tub nestled Near the Scenic Mississippi River!

Romantic Log Cabin Hideaway, Hot tub nestled Near the Scenic Mississippi River!

De Soto WI
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A hot tub is featured at this cabin, along with a garden and laundry facilities. Barbecue grills are provided for your convenience.
Hot Tub
Kitchen
Cozy 3-bedroom cabin - sleeps 10- HOT TUB- river view

Cozy 3-bedroom cabin - sleeps 10- HOT TUB- river view

2 out of 5
De Soto WI
$230 nightly
The price is $243 total per night
$243 total
Jan 8 - Jan 9, 2026
Total with taxes and fees
A hot tub is featured at this cabin, along with barbecue grills.
Hot Tub
Kitchen
Rustic Hideaway Sleeps 4 HOT TUB

Rustic Hideaway Sleeps 4 HOT TUB

De Soto WI
$380 nightly
The price is $431 total per night
$431 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This cabin features a gym and a hot tub. Laundry facilities and barbecue grills are also provided.
Hot Tub
Kitchen
Gundersen Hotel & Suites

Gundersen Hotel & Suites

2.5 out of 5
1520 Clinic Court La Crosse WI
Free Cancellation
Reserve now, pay when you stay
$134 nightly
The price is $154 total per night
$154 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
Romantic Get-a-Way!! 1954 Rail Road Caboose!! Relaxing Hot Tub!

Romantic Get-a-Way!! 1954 Rail Road Caboose!! Relaxing Hot Tub!

Ferryville WI
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A hot tub is featured at this vacation home, along with a garden and barbecue grills.
Hot Tub
Kitchen
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See all available properties in De Soto
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much are vacation packages to De Soto?
Travelocity has package deals to De Soto, including hotels and flights, starting from an impressive $619. With all that extra cash, you could purchase some cool tours or even add on some extra days to your vacation.
Where can I get the best vacation package deals for De Soto?
One word — Travelocity. With as many as 400 partner airlines and 1,000,000 worldwide properties, it's a breeze to put together a De Soto package deal that suits your travel style.
Why should I purchase my De Soto vacation package with Travelocity?
From amazing destinations to one-of-a-kind experiences, we have everything you need to satisfy your travel desires. Our 24/7 customer care will also ensure you're being well taken care of while you're on your trip. And don't stress if you spot a cheaper price on your booking, we'll match it. That's our Price Match Guarantee.
Can I save on my De Soto car rental if I book it with my hotel or flight?
Certainly — combine your hotel, flight and car into a De Soto vacation package and you'll save plenty. With so much to uncover in De Soto, that set of wheels will make exploring easy. Once you've settled into the driver's seat, put the stereo on and head to University of Wisconsin-Madison, a renowned attraction approximately 90 mi from De Soto.
What is the best time of year to go to De Soto?
If budget is what's driving your travel plans, you'll score the best deals in . is typically the costliest time of year. Most people venture here around April, May and June. If you want to avoid the hustle and bustle, you'll find it more peaceful during November, December and January.
Which airport is best for De Soto?
The top airport for De Soto is La Crosse Municipal Airport (LSE). It's located 30 mi south of the downtown area.
Where should I stay when visiting De Soto?
The The Driftless Cottage - A Modern Cabin In The Woods is recommended by many travelers. Book soon before it's too late.

Photos of local treasures

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