Cheap Flights to Santa Cruz from $114

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How Much Does it Cost To Fly To Santa Cruz?

The cheapest prices found with in the last 7 days for return flights were $171 and $114 for one-way flights to Santa Cruz for the period specified. Prices and availability are subject to change. Additional terms apply

Thu, Nov 26 - Tue, Dec 1
MVD
Carrasco Intl.
SCL
Arturo Merino Benitez
$179 Roundtrip, found 2 hours ago
$179
Roundtrip
found 2 hours ago
Select SKY AIRLINE flight, departing Thu, Nov 26 from Carrasco Intl. to Arturo Merino Benitez, returning Tue, Dec 1, priced at $179 found 2 hours ago
Tue, Oct 27 - Mon, Nov 16
MIA
Miami Intl.
SCL
Arturo Merino Benitez
$366 Roundtrip, found 5 days ago
$366
Roundtrip
found 5 days ago
Select Arajet flight, departing Tue, Oct 27 from Miami Intl. to Arturo Merino Benitez, returning Mon, Nov 16, priced at $366 found 5 days ago
OriginDestinationTravel DatesFlights From*
EZESantiagoSeptember 25 to September 27$171
GRUSantiagoOctober 17 to October 24$199
MIASantiagoNovember 6 to November 16$434
LAXSantiagoOctober 4 to October 15$621
YYZSantiagoOctober 5 to October 12$637
JFKSantiagoAugust 26 to August 28$661
LGASantiagoAugust 26 to August 28$671
MADSantiagoSeptember 1 to February 28$861
CCSSantiagoOctober 1 to October 8$962
FCOSantiagoOctober 30 to November 15$1,189
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
GRUSantiagoAugust 14 to August 16$320
EZESantiagoAugust 15 to August 22$354
YYZSantiagoAugust 16 to August 21$774
MIASantiagoAugust 15 to August 21$826
LAXSantiagoAugust 16 to October 16$896
JFKSantiagoAugust 16 to August 25$1,007
LGASantiagoAugust 14 to August 21$1,037
*Prices include taxes and fees

Santa Cruz Flight Information

Traveling to
Santa Cruz
Lowest Price
$171
Number of Airlines Serving
Airlines Serving
SKY AIRLINE, Arajet
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Luxury Hotels in Santa Cruz

TerraViña

TerraViña

3 out of 5
Camino Los Boldos S/n Santa Cruz O'Higgins
$150 nightly
The price is $150 total per night from Aug 13 to Aug 14
$150 total
Aug 13 - Aug 14
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Laura Hartwig Winery and Plaza ...
9.2/10 Wonderful! (219 reviews)
"The staff were very friendly and knowledgeable of the local restaurants and wineries. The room has a balcony which was fabulous. Properly was well maintained and beautiful. Definitely would come back to this property."

Reviewed on Aug 7, 2026

Opens in a new windowTerraViña
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Santa Cruz

Hotel Boutique Vendimia Premium

Hotel Boutique Vendimia Premium

3.5 out of 5
Ismael Valdes 92 Santa Cruz O'Higgins
$102 nightly
The price is $102 total per night from Sep 6 to Sep 7
$102 total
Sep 6 - Sep 7
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Museo de Colchagua and Plaza ...
Opens in a new windowHotel Boutique Vendimia Premium
Santa Cruz Plaza
Great for families

Santa Cruz Plaza

4 out of 5
Plaza De Armas 286 Santa Cruz O'Higgins
$96 nightly
The price is $96 total per night from Aug 13 to Aug 14
$96 total
Aug 13 - Aug 14
Book a stay at this spa hotel in Santa Cruz. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
Opens in a new windowSanta Cruz Plaza
La Perla Hotel

La Perla Hotel

3.5 out of 5
El Rosal, Parcela 4, Lote A, Capellanía Santa Cruz O'Higgins
$83 nightly
The price is $83 total per night from Sep 1 to Sep 2
$83 total
Sep 1 - Sep 2
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Museo de Colchagua and Plaza ...
Opens in a new windowLa Perla Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best Santa Cruz Flight and Hotel Packages

Santa Cruz flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
Hotel Nodo - El primer hotel de negocios en Chile

Hotel Nodo - El primer hotel de negocios en Chile

3.5 out of 5
Price was $662, price is now $432 per person
$432
per person
Sep 16 - Sep 20
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Santiago (SCL)
Aubrey Hotel Boutique

Aubrey Hotel Boutique

4 out of 5
Save 100% on your flight
Price was $935, price is now $529 per person
$529
per person
Sep 16 - Sep 20
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Santiago (SCL)
Hotel Las Majadas

Hotel Las Majadas

4.5 out of 5
Save 100% on your flight
Price was $1,325, price is now $752 per person
$752
per person
Sep 16 - Sep 20
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Santiago (SCL)
Don't see what you're looking for?
See all available trips from Buenos Aires to Santa Cruz
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Need a Car For After Your Flight?

Economy

Chevrolet Spark
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass
  • 5 people
Jeep Compass
SUV Jeep Compass

Frequently asked questions

Which airlines fly to Santa Cruz?
Lock in a fare with one of the 17 airlines that travel to Santa Cruz an enjoy an amazing new adventure. Carriers that come with top reviews include:

  • LATAM Airlines
  • Sky Airline
  • JetSMART

Where to stay in Santa Cruz
Start making those dreams about Santa Cruz come true by reserving your accommodations with Travelocity. With 37 terrific options at your fingertips, we know you'll find the perfect place to lay your head.Securing accommodations can often be a little tiresome. Make the process as easy as possible and check out some of our top suggestions, the Santa Cruz Plaza and the Casa Suiza.
Places to visit in Santa Cruz
Discover the protracted and interesting history of Plaza de Armas. Need some more ideas? A day touring Museo de Colchagua is a wonderful way to learn about regional history away from the crowded tourist sites. And there's more. A trip to Laura Hartwig Winery is a journey for your palate.
How to get through airport security fast when traveling to Santa Cruz
If you like the idea of spending more time at the airport bars and restaurants and less time at the security checkpoint on your way to Santa Cruz, follow these practical tips:

  • Keep your boarding pass and passport easily accessible. They'll be the first things you'll be asked for by security staff.
  • Coins, belts and keys are to be placed in a tub for X-raying. If you walk into the body scanner with these items, you'll be turned around and requested to remove them.
  • Laptops must be removed from their protective carriers and placed in a tub for inspection.
  • When it comes to flying with liquids or gels, each passenger is permitted a quart-sized clear resealable bag to keep containers no larger than 3.4 ounces (100 milliliters).
  • Give some thought to the type of footwear you want to fly in. Slippers are awesome because they're easy to take off for the airport security checks. Try wearing some on your next flight!
  • Some countries have strict biosecurity laws. Consider where you're headed to and whether or not you can travel with unpackaged foods.

Plane Tickets To Santa Cruz

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Santa Cruz. Browse through our inventory to explore a wide range of cheap flights to Santa Cruz to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Santa Cruz as you anxiously await to exit the plane and explore what Santa Cruz has to offer. Considering all the amazing local food and culture in Santa Cruz, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Santa Cruz to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Santa Cruz without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Santa Cruz with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Santa Cruz today!

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.