Cheap Flights to Santa Cruz from $130

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How Much Does it Cost To Fly To Santa Cruz?

The cheapest prices found with in the last 7 days for return flights were $181 and $130 for one-way flights to Santa Cruz for the period specified. Prices and availability are subject to change. Additional terms apply

OriginDestinationTravel DatesFlights From*
EZESantiagoAugust 20 to August 25$181
GRUSantiagoJuly 30 to August 6$234
MIASantiagoSeptember 12 to September 19$443
YYZSantiagoAugust 11 to August 18$512
JFKSantiagoAugust 12 to August 20$646
LGASantiagoAugust 10 to August 12$671
LAXSantiagoAugust 24 to September 6$686
CCSSantiagoAugust 20 to August 26$720
MADSantiagoAugust 23 to October 28$855
FCOSantiagoSeptember 30 to October 28$1,138
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
GRUSantiagoJuly 18 to July 22$318
EZESantiagoJuly 17 to July 20$539
MIASantiagoJuly 19 to August 3$929
LAXSantiagoJuly 19 to July 25$990
JFKSantiagoJuly 18 to July 27$1,034
LGASantiagoJuly 17 to July 20$1,332
FCOSantiagoJuly 17 to July 27$1,364
MADSantiagoJuly 19 to July 26$1,541
*Prices include taxes and fees

Santa Cruz Flight Information

Traveling to
Santa Cruz
Lowest Price
$181
Number of Airlines Serving
Airlines Serving
SKY AIRLINE, United, Copa
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Luxury Hotels in Santa Cruz

TerraViña

TerraViña

3 out of 5
Camino Los Boldos S/n Santa Cruz O'Higgins
$126 nightly
The price is $126 total per night from Jul 14 to Jul 15
$126 total
Jul 14 - Jul 15
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Laura Hartwig Winery and Plaza ...
9.2/10 Wonderful! (218 reviews)
"세번째 방문이지만 여전히 좋은 호텔입니다. 주변의 콜차구아 박물관은 깜짝 놀랄 미이라 머리가 있습니다."

Reviewed on Jun 21, 2026

Opens in a new windowTerraViña
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Santa Cruz

Hotel Boutique Vendimia Premium

Hotel Boutique Vendimia Premium

3.5 out of 5
Ismael Valdes 92 Santa Cruz O'Higgins
$102 nightly
The price is $102 total per night from Aug 6 to Aug 7
$102 total
Aug 6 - Aug 7
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Museo de Colchagua and Plaza ...
Opens in a new windowHotel Boutique Vendimia Premium
Santa Cruz Plaza
Great for families

Santa Cruz Plaza

4 out of 5
Plaza De Armas 286 Santa Cruz O'Higgins
$110 nightly
The price is $110 total per night from Aug 5 to Aug 6
$110 total
Aug 5 - Aug 6
Book a stay at this spa hotel in Santa Cruz. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
Opens in a new windowSanta Cruz Plaza
La Perla Hotel

La Perla Hotel

3.5 out of 5
El Rosal, Parcela 4, Lote A, Capellanía Santa Cruz O'Higgins
$80 nightly
The price is $80 total per night from Jul 14 to Jul 15
$80 total
Jul 14 - Jul 15
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Museo de Colchagua and Plaza ...
Opens in a new windowLa Perla Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Lowest prices found within the past 2 days. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Which airlines fly to Santa Cruz?
Lock in a fare with one of the 17 airlines that travel to Santa Cruz an enjoy an amazing new adventure. Carriers that come with top reviews include:

  • LATAM Airlines
  • Sky Airline
  • JetSMART

Where to stay in Santa Cruz
Start making those dreams about Santa Cruz come true by reserving your accommodations with Travelocity. With 37 terrific options at your fingertips, we know you'll find the perfect place to lay your head.Securing accommodations can often be a little tiresome. Make the process as easy as possible and check out some of our top suggestions, the Santa Cruz Plaza and the Casa Suiza.
Places to visit in Santa Cruz
Discover the protracted and interesting history of Plaza de Armas. Need some more ideas? A day touring Museo de Colchagua is a wonderful way to learn about regional history away from the crowded tourist sites. And there's more. A trip to Laura Hartwig Winery is a journey for your palate.
How to get through airport security fast when traveling to Santa Cruz
If you like the idea of spending more time at the airport bars and restaurants and less time at the security checkpoint on your way to Santa Cruz, follow these practical tips:

  • Keep your boarding pass and passport easily accessible. They'll be the first things you'll be asked for by security staff.
  • Coins, belts and keys are to be placed in a tub for X-raying. If you walk into the body scanner with these items, you'll be turned around and requested to remove them.
  • Laptops must be removed from their protective carriers and placed in a tub for inspection.
  • When it comes to flying with liquids or gels, each passenger is permitted a quart-sized clear resealable bag to keep containers no larger than 3.4 ounces (100 milliliters).
  • Give some thought to the type of footwear you want to fly in. Slippers are awesome because they're easy to take off for the airport security checks. Try wearing some on your next flight!
  • Some countries have strict biosecurity laws. Consider where you're headed to and whether or not you can travel with unpackaged foods.

Plane Tickets To Santa Cruz

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Santa Cruz. Browse through our inventory to explore a wide range of cheap flights to Santa Cruz to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Santa Cruz as you anxiously await to exit the plane and explore what Santa Cruz has to offer. Considering all the amazing local food and culture in Santa Cruz, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Santa Cruz to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Santa Cruz without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Santa Cruz with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Santa Cruz today!

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.