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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Enjoy free breakfast at this spa Cape Girardeau hotel

Choose dates to view prices

Photo gallery for Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A buffet with labeled containers of omelets and other dishes.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
A hotel room with a bed, a desk, a chair, a kitchenette, and a bathroom.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Parking included
  • Free WiFi
  • Air conditioning

Explore the area

View in a map
3253 William Street, Cape Girardeau, MO, 63701
  • Place, Riverfront Bridge Park
    ‪6 min drive‬
  • Place, Southeast Missouri State University
    ‪7 min drive‬
  • Place, Century Casino & Hotel Cape Girardeau
    ‪9 min drive‬
  • Airport, Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪5 min drive‬

Room options

View all photos for Suite, 2 Queen Beds, Accessible (Roll-In Shower)

A hotel room with two beds, a TV, a desk, and a chair.

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

8.0 out of 10
Very good
(6 reviews)
  • 400 sq ft
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Suite, 1 King Bed, Accessible (Roll-In Shower)

A bed with white bedding and pillows against a wooden headboard.

Suite, 1 King Bed, Accessible (Roll-In Shower)

9.6 out of 10
Exceptional
(7 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 King Bed

A hotel room with a bed, a blue sofa, a desk, and a green chair.

Suite, 1 King Bed

9.8 out of 10
Exceptional
(36 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 2 Queen Beds

A bed with white bedding and pillows against a wooden headboard.

Suite, 2 Queen Beds

9.6 out of 10
Exceptional
(65 reviews)
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Suite, 2 Queen Beds, Accessible (Mobility)

A hotel room with two beds, a desk, a chair, a sofa, and a lamp.

Suite, 2 Queen Beds, Accessible (Mobility)

9.4 out of 10
Exceptional
(17 reviews)
  • 400 sq ft
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Standard Room, 1 Queen Bed

A bed with white bedding and pillows against a wooden headboard.

Standard Room, 1 Queen Bed

9.4 out of 10
Exceptional
(6 reviews)
  • 400 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 Queen Bed
  • Free WiFi

View all photos for Standard Room

A bed with white bedding and pillows against a wooden headboard.

Standard Room

8.4 out of 10
Very good
(5 reviews)
  • 400 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom (Feature)

A bed with white bedding and pillows against a wooden headboard.

Suite, 1 Bedroom (Feature)

10.0 out of 10
Exceptional
(1 review)
  • 1 bedroom
  • Sleeps 2
  • 1 Queen Bed
  • Free WiFi

View all photos for Suite, 1 King Bed, Accessible (Mobility)

A bed with white bedding and pillows against a wooden headboard.

Suite, 1 King Bed, Accessible (Mobility)

10.0 out of 10
Exceptional
(2 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

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Total with taxes and fees
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About the neighborhood

Cape Girardeau

Near the airport.A stay at this hotel places you within half a mile (1 km) of Saint Francis Medical Center and 3 miles (5 km) of Saint Francis Healthcare System. Southeast Missouri Hospital and Cape Splash Family Aquatic Center are also within 3 miles (5 km).

What's nearby

  • Cape Splash Family Aquatic Center - 4 min drive - 2.9 miles
  • Riverfront Bridge Park - 6 min drive - 5.0 miles
  • Southeast Missouri State University - 7 min drive - 3.7 miles
  • Century Casino & Hotel Cape Girardeau - 9 min drive - 6.5 miles
  • Giant City State Park - 55 min drive - 49.1 miles

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 10 min drive

Restaurants

  • ‪Chick-fil-A - ‬7 min walk
  • ‪Rhodes - ‬20 min walk
  • ‪McDonald's - ‬10 min walk
  • ‪Panera Bread - ‬2 min walk
  • ‪Taco Bell - ‬12 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Enjoy free breakfast at this spa Cape Girardeau hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers its guests a full-service spa, an indoor pool, and a fitness center. Public spaces have free WiFi and wired Internet. A business center and a meeting room are available. Free breakfast is served. Event space at this hotel measures 118 square feet (11 square meters) and includes conference space. The business-friendly Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG also features a vending machine, complimentary newspapers in the lobby, and laundry facilities. Self parking is free.

This Cape Girardeau hotel is smoke free.

  • 1 building
  • 102 guestrooms or units
  • 4 levels
  • 118 sq ft of conference space
  • 11 sq m of conference space
  • Breakfast available (free)
  • Poolside lounge chairs
  • Business facilities
  • Conference space
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Storage area for luggage
  • Front-desk safe
  • Newspapers in lobby (free)
  • Bellhop
  • No smoking on site
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers 102 accommodations with safes and coffee/tea makers. Accommodations offer separate sitting areas. Pillowtop beds feature down comforters and premium bedding. A pillow menu is available. 52-inch flat-screen televisions come with premium cable channels. Bathrooms include complimentary toiletries and hair dryers.

Guests can surf the web using the complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Housekeeping is provided daily.

Guests can indulge in a pampering treatment at the hotel's full-service spa.

Similar properties

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
  • Pool
  • Hot tub
  • Breakfast included
  • Pet friendly
4.8 out of 5, Exceptional, 1,003 reviews
$100 nightly
The price is $113
Jul 12 - Jul 13
Total with taxes and fees
Drury Plaza Hotel Cape Girardeau Conference Center

Property amenities

Family friendly

  • In-room microwave
  • Indoor pool
  • Laundry facilities
  • Mini-fridge

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking available

Food and drink

  • Free breakfast available

Things to do

  • Full-service spa
  • Gym
  • Indoor pool

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator

Room amenities

Entertainment

  • 52-inch flat-screen TV with premium cable channels

Bedroom

  • Down comforter
  • Pillow menu
  • Pillowtop mattress
  • Premium bedding

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Food and drink

  • Coffee/tea maker
  • Microwave
  • Mini-fridge

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • No pets allowed

Children and extra beds

  • Children are welcome.
  • Cribs (infant beds) are not available.

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a fire extinguisher and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, JCB International, and Carte Blanche. Cash is not accepted. For guests' safety, the property includes a fire extinguisher and a smoke detector in each accommodation. Cashless payment methods are available for all transactions. This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

We should mention

  • Pool access available from 8 AM to 11 PM.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Cape Girardeau I-55
Holiday Inn Express Hotel Cape Girardeau I-55
Holiday Inn Hotel I-55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Inn Express Cape Girarau I55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Frequently asked questions

How close is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG to the airport?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is 6.1 mi (10-min drive) away from the Cape Girardeau, MO (CGI-Cape Girardeau Municipal) airport, the closest popular airport to the property.

How much does it cost to stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

As of Jul 4, 2026, prices found for a 1-night stay for 2 adults at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG on Jul 16, 2026 start from $124, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have an airport shuttle?

Airport shuttle services are not available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offer free breakfast?

Yes, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers free breakfast.

Is there a casino at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

No, there is no casino at this hotel, but Century Casino & Hotel Cape Girardeau (8-min drive) is nearby.

What time is check-in at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Check-in start time: 3:00 PM; Check-in end time: anytime.

Is there free parking at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

This hotel offers free self parking.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a pool?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG features an indoor pool. Guests can enjoy pool access from 8 AM to 11 PM.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a spa?

Yes, this hotel has a spa.

How close is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG to downtown Cape Girardeau?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is 3.2 mi away from Cape Girardeau.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 775 out of 1000 reviews
Rating 8 - Good. 149 out of 1000 reviews
Rating 6 - Okay. 41 out of 1000 reviews
Rating 4 - Poor. 16 out of 1000 reviews
Rating 2 - Terrible. 19 out of 1000 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.4/10

Amenities

9.6/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

Sarah

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, large rooms, comfortable beds, friendly staff, huge breakfast room and nice breakfast selection. Would absolutely stay here again!
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

Sarah

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, large rooms, comfortable beds, friendly staff, huge breakfast room and nice breakfast selection. Would absolutely stay here again!
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel is in a convenient central area. Was clean and staff was friendly.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Heather

Liked: Cleanliness, staff & service, amenities
Room was clean, breakfast was nice.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Amber

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was probably the cleanest hotel we have ever stayed in. The beds were also very comfortable. Staff was also friendly and helpful.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

RYAN

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great Staff!
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Vanessa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This hotel was recommended by a friend of ours. The hotel staff were great. It was clean and quiet. Me and my husband enjoyed our stay.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Arriel

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room staff is very nice parking it great
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

John

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Everything was excellent. Staff was very friendly and helpful.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Bryan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent place to stay.
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Rex

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was very good and staff was extremely friendly and rooms were very clean
Stayed 2 nights in Jan 2026
Verified

10/10 Excellent

Janelle

lovely hotel
Stayed 2 nights in Dec 2025
Verified

10/10 Excellent

Andrew

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I was amazed to find out this place is 20+ years old. It is in great shape. Room was wonderful. Breakfast was great; very lovely stay.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Nancy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was very clean. Very quiet even though the hotel was full. Breakfast was wonderful.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Lindsay

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, organized, and well maintain property
Stayed 1 night in Mar 2026
Verified

8/10 Good

Mary

Liked: Cleanliness, staff & service, amenities
Clean, courteous staff
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Nellie

Liked: Cleanliness, amenities, property conditions & facilities
Clean room and staff was very friendly.
Stayed 2 nights in Nov 2025
Verified

10/10 Excellent

NICOLE

Liked: Cleanliness, amenities, property conditions & facilities
Everything and Everyone was awesome
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Summer

Liked: Cleanliness, staff & service, amenities
It was amazing check in to check out
Stayed 1 night in Aug 2025
Verified

10/10 Excellent

Robbie

Your hotel was a very nice place staff was wonderful !! Very clean !!! Easy parking !! Great room !!! Love it Breakfast was hot and ready to go . At 6 am
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Marcus

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful room, whirlpool bath, breakfast, staff
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Mike

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place to stay.
Stayed 1 night in Jun 2025
Verified

10/10 Excellent

John

Liked: Amenities
Room was prestine and the buffet was excellent!!
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Deborah

Liked: Cleanliness, staff & service, amenities
Room was spacious and clean. Staff was nice and helpful. Good breakfast.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Dawn

Liked: Cleanliness, amenities, property conditions & facilities
Everyone kind & place very clean.
Stayed 1 night in Jan 2026

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