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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Enjoy free breakfast at this spa Cape Girardeau hotel

Choose dates to view prices

Photo gallery for Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Exterior
Premium bedding, down comforters, pillowtop beds, in-room safe
Exterior
Free breakfast
Indoor pool, open 8 AM to 11 PM, sun loungers

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Parking included
  • Free WiFi
  • Air conditioning

Explore the area

View in a map
3253 William Street, Cape Girardeau, MO, 63701
  • Place, Saint Francis Medical Center
    ‪6 min walk‬
  • Place, Southeast Missouri State University
    ‪6 min drive‬
  • Place, Isle Casino Cape Girardeau
    ‪8 min drive‬
  • Airport, Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪5 min drive‬

Room options

View all photos for Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Suite, 2 Queen Beds, Accessible (Roll-In Shower) | Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

8.0 out of 10
Very good
(6 reviews)
  • 400 sq ft
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 1 King Bed, Accessible (Roll-In Shower)

9.4 out of 10
Exceptional
(6 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 1 King Bed

9.6 out of 10
Exceptional
(32 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 2 Queen Beds

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 2 Queen Beds

9.6 out of 10
Exceptional
(54 reviews)
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 2 Queen Beds, Accessible (Mobility)

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 2 Queen Beds, Accessible (Mobility)

9.4 out of 10
Exceptional
(14 reviews)
  • 400 sq ft
  • Sleeps 6
  • 2 Queen Beds

View all photos for Standard Room, 1 Queen Bed

Premium bedding, down comforters, pillowtop beds, in-room safe

Standard Room, 1 Queen Bed

9.2 out of 10
Wonderful
(5 reviews)
  • 400 sq ft
  • Sleeps 2
  • 1 Queen Bed

View all photos for Standard Room

Premium bedding, down comforters, pillowtop beds, in-room safe

Standard Room

8.4 out of 10
Very good
(5 reviews)
  • 400 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 Bedroom (Feature)

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 1 Bedroom (Feature)

10.0 out of 10
Exceptional
(1 review)
  • Sleeps 2
  • 1 Queen Bed

View all photos for Suite, 1 King Bed, Accessible (Mobility)

Premium bedding, down comforters, pillowtop beds, in-room safe

Suite, 1 King Bed, Accessible (Mobility)

10.0 out of 10
Exceptional
(2 reviews)
  • Sleeps 2
  • 1 King Bed

About the neighborhood

Cape Girardeau

Near the airport.A stay at this hotel places you within half a mile (1 km) of Saint Francis Medical Center and 3 miles (5 km) of Saint Francis Healthcare System. Southeast Missouri Hospital and Cape Splash Family Aquatic Center are also within 3 miles (5 km).

What's nearby

  • Saint Francis Medical Center - 6 min walk - 0.4 miles
  • Riverfront Bridge Park - 6 min drive - 4.4 miles
  • Southeast Missouri State University - 6 min drive - 3.9 miles
  • Isle Casino Cape Girardeau - 8 min drive - 5.7 miles
  • Show Me Center - 9 min drive - 5.7 miles

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 10 min drive

Restaurants

  • ‪Chick-fil-A - ‬7 min walk
  • ‪Rhodes - ‬20 min walk
  • ‪McDonald's - ‬10 min walk
  • ‪White Castle - ‬10 min walk
  • ‪Wings Etc. - ‬9 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Enjoy free breakfast at this spa Cape Girardeau hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers its guests a full-service spa, an indoor pool, and a fitness center. Public spaces have free WiFi and wired Internet. A business center and a meeting room are available. Free breakfast is served. Event space at this hotel measures 118 square feet (11 square meters) and includes conference space. The business-friendly Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG also features a vending machine, complimentary newspapers in the lobby, and laundry facilities. Self parking is free.

This Cape Girardeau hotel is smoke free.

  • 1 building
  • 102 guestrooms or units
  • 4 levels
  • 118 sq ft of conference space
  • 11 sq m of conference space
  • Breakfast available (free)
  • Poolside lounge chairs
  • Business facilities
  • Conference space
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Storage area for luggage
  • Front-desk safe
  • Newspapers in lobby (free)
  • Bellhop
  • No smoking on site
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers 102 accommodations with safes and coffee/tea makers. Accommodations offer separate sitting areas. Pillowtop beds feature down comforters and premium bedding. A pillow menu is available. 52-inch flat-screen televisions come with premium cable channels. Bathrooms include complimentary toiletries and hair dryers.

Guests can surf the web using the complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Housekeeping is provided daily.

Guests can indulge in a pampering treatment at the hotel's full-service spa.

Similar properties

Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau
  • Pool
  • Breakfast included
  • Parking included
  • Free WiFi
4.7 out of 5, Exceptional, 147 reviews
$88 nightly
The price is $99
Jan 11 - Jan 12
Total with taxes and fees
Fairfield Inn & Suites by Marriott Cape Girardeau

Property amenities

Family friendly

  • In-room microwave
  • Indoor pool
  • Laundry facilities
  • Mini-fridge

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Limited onsite self parking
  • Wheelchair-accessible parking available

Food and drink

  • Free breakfast available

Things to do

  • Full-service spa
  • Gym
  • Indoor pool

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator

Room amenities

Entertainment

  • 52-inch flat-screen TV with premium cable channels

Bedroom

  • Down comforter
  • Pillow menu
  • Pillowtop mattress
  • Premium bedding

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Food and drink

  • Coffee/tea maker
  • Microwave
  • Mini-fridge

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • No pets allowed

Children and extra beds

  • Children are welcome.
  • Cribs (infant beds) are not available.

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, JCB International, and Carte Blanche. Cash is not accepted. For guests' safety, the property includes a smoke detector in each accommodation. Cashless payment methods are available for all transactions. This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

We should mention

  • Pool access available from 8 AM to 11 PM.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Cape Girardeau I-55
Holiday Inn Express Hotel Cape Girardeau I-55
Holiday Inn Hotel I-55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Inn Express Cape Girarau I55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Frequently asked questions

How close is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG to the airport?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is 6.1 mi (10-min drive) away from the Cape Girardeau, MO (CGI-Cape Girardeau Municipal) airport, the closest popular airport to the property.

How much does it cost to stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

As of Jan 4, 2026, prices found for a 1-night stay for 2 adults at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG on Jan 11, 2026 start from $91.0, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have an airport shuttle?

Airport shuttle services are not available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offer free breakfast?

Yes, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers free breakfast.

Is there a casino at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

No, there is no casino at this hotel, but Isle Casino Cape Girardeau (7-min drive) is nearby.

What time is check-in at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Check-in start time: 3:00 PM; Check-in end time: anytime.

Is there free parking at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

This hotel offers free self parking.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a pool?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG features an indoor pool. Guests can enjoy pool access from 8 AM to 11 PM.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a spa?

Yes, this hotel has a spa.

How close is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG to downtown Cape Girardeau?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is 3.2 mi away from Cape Girardeau.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 782 out of 1003 reviews
Rating 8 - Good. 150 out of 1003 reviews
Rating 6 - Okay. 38 out of 1003 reviews
Rating 4 - Poor. 16 out of 1003 reviews
Rating 2 - Terrible. 17 out of 1003 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.2/10

Amenities

9.6/10

Property conditions & facilities

9.4/10

Eco-friendliness

Reviews

10/10 Excellent

Bryan

Traveled with family and small children, Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent place to stay.
Stayed 1 night in Nov 2025

10/10 Excellent

Malinda

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Oct 2025

10/10 Excellent

Jane

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel staff at checkin very friendly & helpful. Many dining options within walking distance of hotel. Beds comfy and room clean
Stayed 1 night in Oct 2025

4/10 Poor

James E. Askew

Disliked: Cleanliness, property conditions & facilities
The room was dirty and old
Stayed 1 night in Sep 2025

10/10 Excellent

Jerry

Stayed 2 nights in Sep 2025

10/10 Excellent

John Charles

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Excellent
Stayed 2 nights in Sep 2025

10/10 Excellent

David

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great staff and clean rooms.
Stayed 1 night in Sep 2025

8/10 Good

Mark

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The beds were so uncomfortable and the pillows were worse. I did not sleep well. The breakfast buffet was nice, but the sausage was served cold and it gave us all a stomach ache. The whole hotel was very clean and the staff were all very nice. They even gave me a free tooth rush because I had forgotten mine at home.
Stayed 1 night in Sep 2025

8/10 Good

Douglas

Liked: Cleanliness, staff & service, property conditions & facilities
No shuttle service
Stayed 1 night in Sep 2025

10/10 Excellent

Debra

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Everything was wonderful.
Stayed 2 nights in Jul 2025

10/10 Excellent

Cherish

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We got greeted with such a friendly smile and attitude as soon as we got in. The room was clean and roomy. Would highly recommend and come back.
Stayed 1 night in Sep 2025

10/10 Excellent

Lynn

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Sep 2025

10/10 Excellent

Kelly

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was right off the interstate with lots of restaurant options
Stayed 1 night in Sep 2025

8/10 Good

Terri

Stayed 3 nights in May 2025

8/10 Good

David, Caruthersville

Traveled with partner
Liked: Cleanliness, staff & service, amenities
The hotel itself was very warm, along with the room which the thermostat did not work correctly. But no complaints other than that
Stayed 1 night in Sep 2025

10/10 Excellent

Shana

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Aug 2025

10/10 Excellent

Darlene Cassidy

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Nice hotel

Great
Stayed 1 night in Sep 2025

10/10 Excellent

Richie

Stayed 1 night in Sep 2025

10/10 Excellent

Douglas

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Sep 2025

10/10 Excellent

Suzanne

Traveled with family
Liked: Staff & service, property conditions & facilities
Everything was good except for our bathroom not being really clean.
Stayed 1 night in Sep 2025

10/10 Excellent

Laura

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Lovely stay

Our stay was wonderful. The rooms are so nice. Bed was comfortable. The jaccuzi tub is excellent. The free breakfast was lovely. Even had healthy options with turkey sausage and egg white omelets. Delicious.
Stayed 1 night in Aug 2025

10/10 Excellent

Christian

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Aug 2025

10/10 Excellent

Carey

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very Friendly check in Parking lot was very Safe A lot of know restaurants within walking distance from Hotel,Very Clean.
Stayed 2 nights in Aug 2025

10/10 Excellent

Gay

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Felt like I was in a mansion.
Stayed 1 night in Aug 2025

6/10 Okay

Jessica

Stayed 1 night in Aug 2025